DRSC/TRiP Functional Genomics Resources

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Protein Alignment trv and SRSF1

DIOPT Version :9

Sequence 1:NP_001163754.3 Gene:trv / 43362 FlyBaseID:FBgn0085391 Length:651 Species:Drosophila melanogaster
Sequence 2:NP_008855.1 Gene:SRSF1 / 6426 HGNCID:10780 Length:248 Species:Homo sapiens


Alignment Length:214 Identity:43/214 - (20%)
Similarity:73/214 - (34%) Gaps:79/214 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   306 PPLHKQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSK----GYGFVSFIKKSEA 366
            |..:....|:||:|..:|.|:.:.:.|..:|.|.|.       .||::    .:.||.|....:|
Human    10 PAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDI-------DLKNRRGGPPFAFVEFEDPRDA 67

  Fly   367 ESAITAMNGQWLGSRSIRTNW------------------ATR---KPPASKENIKPLTFDEVYNQ 410
            |.|:...:|.......:|..:                  |.|   .||:.:              
Human    68 EDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRR-------------- 118

  Fly   411 SSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIR-------------VFKDKGYAFVRFS 462
               |...|.|.|:                .|.|:.|:::             |::| |...|.|.
Human   119 ---SENRVVVSGL----------------PPSGSWQDLKDHMREAGDVCYADVYRD-GTGVVEFV 163

  Fly   463 TKEAATHAIVGVHNTEINA 481
            .||..|:|:..:.||:..:
Human   164 RKEDMTYAVRKLDNTKFRS 182

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trvNP_001163754.3 RRM2_TIA1_like 313..387 CDD:240799 20/77 (26%)
RRM3_TIA1_like 416..491 CDD:240800 17/79 (22%)
SRSF1NP_008855.1 RRM1_SRSF1 12..90 CDD:410010 20/84 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 88..134 10/78 (13%)
RRM2_SRSF1 113..196 CDD:410160 20/104 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..248
Interaction with SAFB1 198..247
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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