DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and hnrnpd

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001103930.1	Gene:	hnrnpd / 560522	ZFINID:	ZDB-GENE-070424-97	Length:	314	Species:	Danio rerio

Alignment Length:	322	Identity:	73/322 - (22%)
Similarity:	116/322 - (36%)	Gaps:	103/322 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 EGGGQDMEDSDEEMEYMPPLHKQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSK 353
            ||...|...::|:         :..:|||.||.:...:.|::.||.|||:.||.:..||.|.:|:
Zfish    40 EGSKIDASKNEED---------EGKMFVGGLSWDTTKKDLKDYFTKFGEVVDCTLKLDPLTGRSR 95

  Fly   354 GYGFVSFIKKSEAESAIT----AMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPS 414
            |:|||.|.:....|..||    .:||:.:..:.       .|...:||.:|
Zfish    96 GFGFVLFKEAESVEKVITQKEHKLNGKVIDPKK-------AKAMKTKEPVK-------------- 139

  Fly   415 NCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEI------RVFKDKGYAFVRFSTKEAATHAIVG 473
              .::|||::   ....||.:::.|..||.::.|      :..|.:|:.|:.|..:|.....:..
Zfish   140 --KIFVGGLS---PDTPEEKIREYFDAYGEVESIELPMENKTNKRRGFCFITFKEEEPVKKIMEK 199

  Fly   474 V-HNTEINAQPVKCSWGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATG 537
            : ||..::...||.:..||.                                    |.||....|
Zfish   200 MYHNIGLSKCEVKVAMSKEQ------------------------------------YQQQQQWGG 228

  Fly   538 CWYSPTPTYPASSATAAAVTPAAASAAAVQNQFLQGI-----QGY-HFGQYGGYQQGYMGMG 593
                           ....|............:.||.     ||| ::|.||...|||.|.|
Zfish   229 ---------------RGGYTSRGRGRGGPNQNWNQGYGNYWNQGYGNYGNYGYNNQGYGGYG 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	27/77 (35%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	18/81 (22%)
hnrnpd	NP_001103930.1	CBFNT	3..54	CDD:285369	4/22 (18%)
		RRM1_hnRNPD_like	56..129	CDD:241019	27/79 (34%)
		RRM2_hnRNPD	140..214	CDD:241027	18/76 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910