DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and hnrnpa2b1

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001192271.1	Gene:	hnrnpa2b1 / 549680	XenbaseID:	XB-GENE-490993	Length:	350	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	73/301 - (24%)
Similarity:	116/301 - (38%)	Gaps:	88/301 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 KQFH-IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAM 373
            :||. :|:|.||.|.....||..:..:|:::||.|:|||.:.:|:|:|||:|....|.::::.|
Frog     6 EQFRKLFIGGLSFETTEDSLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMDEVDASMAA- 69

  Fly   374 NGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTV---YVGGVNSALTALSEEVL 435
            ....:..|.:.    .::..|.:|:.||           .::.||   :|||:..   ...|..|
Frog    70 RPHTIDGRVVE----PKRAVAREESAKP-----------GAHVTVKKLFVGGIKE---DTEEHHL 116

  Fly   436 QKTFAPYGAIQEIRVFKDK------GYAFVRFSTKEAAT-------HAIVGVHNTEINAQPVKCS 487
            ::.|..||.|:.|.:..||      |:.||.|...:...       |.|.| ||.|:.    |..
Frog   117 REYFEEYGKIESIEIITDKQSGKKRGFGFVTFDDHDPVDKIVLQKYHTING-HNAEVR----KAL 176

  Fly   488 WGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSAT 552
            ..:|..|..|.:.            :.|..:|.|.:.....:|.         .|...:..||
Frog   177 SKQEMQDVQNTRN------------SRGGNFGFGDSRGGGNFGS---------GPGGNFRGSS-- 218

  Fly   553 AAAVTPAAASAAAVQNQFLQGIQGYHFGQYGGYQQGYMGMG 593
                                  .||..|:  ||..||.|.|
Frog   219 ----------------------DGYGGGR--GYGDGYNGYG 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	23/74 (31%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	25/90 (28%)
hnrnpa2b1	NP_001192271.1	RRM1_hnRNPA2B1	7..87	CDD:241206	25/84 (30%)
		RRM2_hnRNPA2B1	100..179	CDD:241025	23/86 (27%)
		HnRNPA1	294..319	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000