DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and hnrnpa1

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	XP_012812298.1	Gene:	hnrnpa1 / 496507	XenbaseID:	XB-GENE-493963	Length:	362	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	74/308 - (24%)
Similarity:	118/308 - (38%)	Gaps:	61/308 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWL 378
            :|:|.||.|...:.|||.|..:|.::||.|:|||.:.:|:|:|||::....|.::|::|...: :
Frog    16 LFIGGLSFETTDESLREHFEQWGTLTDCVVMRDPNSKRSRGFGFVTYSSTDEVDAAMSARPHK-V 79

  Fly   379 GSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYG 443
            ..|.:....|..:..:|:.... ||..:           ::|||:..   ...|..|::.|..||
Frog    80 DGRVVEPKRAVSREDSSRPGAH-LTVKK-----------IFVGGIKE---DTEEHHLREYFEQYG 129

  Fly   444 AIQEIRVFKD------KGYAFVRFSTKEAATHAI------VGVHNTEI----NAQPVKCSWGKES 492
            .|:.|.:..|      :|:|||.|...::....:      |..||.|:    :.|.:....|.:.
Frog   130 KIEVIEIMTDRGSGKKRGFAFVTFEDHDSVDKIVIQKYHTVNNHNCEVRKALSKQEMASVSGSQR 194

  Fly   493 GDPNNAQTIATQALNSAAAAAAG--FPYGVGAAAAAAAYG----QQLAATGCWYSPTPTYPASSA 551
            |...:..........:......|  |....|.......||    ......| .|..:|.|...:.
Frog   195 GRGGSGNFSGRGGFGNDNFGGRGGNFSSNRGGGFGNRGYGGDGYNGFGNDG-GYGGSPPYSGGNR 258

  Fly   552 TAAAVTPAAASAAAVQNQFLQGIQGYHFGQYGGY------QQGYMGMG 593
            ....                .|.|||..||.|||      ..||.|.|
Frog   259 GYGG----------------GGGQGYGGGQGGGYGGGNGGYDGYNGGG 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	25/72 (35%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	22/90 (24%)
hnrnpa1	XP_012812298.1	RRM1_hnRNPA1	12..92	CDD:241205	26/76 (34%)
		RRM2_hnRNPA1	105..181	CDD:241024	20/89 (22%)
		HnRNPA1	<315..>334	CDD:371635
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910