DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and hnrnpdl

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001011015.1	Gene:	hnrnpdl / 496424	XenbaseID:	XB-GENE-495016	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	291	Identity:	70/291 - (24%)
Similarity:	113/291 - (38%)	Gaps:	62/291 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWL 378
            :|:|.||.:...:.|.|..:.|||:.||.:..||.|.:|:|:|||.|      :.|:
Frog    28 MFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLF------KDAV-------- 78

  Fly   379 GSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYG 443
               |:.....|::.....:.|.|.....:..:..|..  |:|||::...|   ||.:::.|..:|
Frog    79 ---SVDKVLETKEHKLDGKLIDPKRAKALKGKEPPKK--VFVGGLSPETT---EEQIKQYFGGFG 135

  Fly   444 AIQEIRVFKD------KGYAFVRFSTKEAATHAI------VGVHNTEIN-AQPVKCSWGKESGDP 495
            .|:.|.:..|      :|:.||.::.:|.....:      :|....||. |||.:....::....
Frog   136 EIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLESRFHQIGTGKCEIKVAQPKEVYRQQQQKQQ 200

  Fly   496 NNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVTPAA 560
            ...:..||     ....|.|...|.|.....:.|..|...:   |....:|
Frog   201 KGGRGAAT-----GRGGARGRGRGQGWNQGYSNYYDQNYGS---YGNNGSY-------------- 243

  Fly   561 ASAAAVQNQFLQG--IQGYHFGQYGGYQQGY 589
              |....|....|  ..||::|.| ||.|||
Frog   244 --ADQGYNNSYSGYDYSGYNYGSY-GYNQGY 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	22/72 (31%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	22/87 (25%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		RRM1_hnRPDL	27..102	CDD:410152	25/90 (28%)
		RRM2_hnRPDL	112..186	CDD:409998	19/78 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..224		6/36 (17%)
		Trnau1ap	222..>278	CDD:407550	16/70 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910