DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and hnrnpa0a

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_997810.2	Gene:	hnrnpa0a / 323529	ZFINID:	ZDB-GENE-030131-2249	Length:	305	Species:	Danio rerio

Alignment Length:	294	Identity:	70/294 - (23%)
Similarity:	113/294 - (38%)	Gaps:	78/294 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITA----MN 374
            :|||.|:.:.....||..|..:|:::||.||::.|..:|:.:|||::....||:||::|    ::
Zfish    12 LFVGGLNVQTTDDGLRNHFEQYGKLTDCVVVQNQQLKRSRCFGFVTYSSPDEADSAMSARPHILD 76

  Fly   375 GQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTF 439
            |         .|...::..|.::..||....:|..        :::||:..   .:.|:.|:..|
Zfish    77 G---------NNVELKRAVAREDAGKPEALAKVKK--------IFIGGLKD---DIEEDHLRDCF 121

  Fly   440 APYGAIQEIRVFKDK------GYAFVRFSTKEAATHA------IVGVHNTEINAQPVKCSWGKES 492
            :.:||:::..|..||      |:.||.|...::|..|      |:..|..|     ||.:..|:.
Zfish   122 SQFGAVEKAEVITDKETGKKRGFGFVYFEDNDSADKAVVLKFHIINGHKVE-----VKKALTKQE 181

  Fly   493 GDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVT 557
                      .||..|......|...|.|.......||.:....|       .|....
Zfish   182 ----------MQAAGSRGGGRGGRGGGRGMGRPQNGYGGRGGGYG-------NYGGGG------- 222

  Fly   558 PAAASAAAVQNQFLQGIQGYHFGQYGGYQQGYMG 591
                         ..|..||..|..|||..||.|
Zfish   223 -------------YGGNDGYGGGYGGGYGGGYGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	23/76 (30%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	21/86 (24%)
hnrnpa0a	NP_997810.2	RRM1_hnRNPA0	8..86	CDD:240772	24/82 (29%)
		RRM_SF	102..181	CDD:302621	22/94 (23%)
		HnRNPA1	260..286	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910