DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trv and csx1

DIOPT Version :9

Sequence 1:	NP_001163754.3	Gene:	trv / 43362	FlyBaseID:	FBgn0085391	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_594243.1	Gene:	csx1 / 2542151	PomBaseID:	SPAC17A2.09c	Length:	632	Species:	Schizosaccharomyces pombe

Alignment Length:	361	Identity:	96/361 - (26%)
Similarity:	154/361 - (42%)	Gaps:	52/361 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 QFHIFVGDLSSEIETQQLREAFTPFGEI----SDCRVVRDPQTLKSKGYGFVSFIKKSEAESAIT 371
            :|.||||||   :.|.:..:.|..|..|    :..:::.||.|..|:.||||.|..:.|.:.|:.
pombe   181 EFSIFVGDL---LPTTEDSDLFMTFRSIYPSCTSAKIIVDPVTGLSRKYGFVRFSSEKEQQHALM 242

  Fly   372 AMNGQWLGSRSIRTNWATRKP-------------PASKENIKPLTFDEVYNQS----SPSNCTVY 419
            .|.|.....|.:|.:.|:.|.             |.|..|.:|       ||.    .|.|.||:
pombe   243 HMQGYLCQGRPLRISVASPKSRASIAADSALGIVPTSTSNRQP-------NQDLCSMDPLNTTVF 300

  Fly   420 VGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPV 484
            |||:.|   .|||:.||..|.|:|.|..|::...||..||::|.|.||..||..:....:....:
pombe   301 VGGLAS---NLSEKDLQVCFQPFGRILNIKIPFGKGCGFVQYSEKSAAEKAINTMQGALVGTSHI 362

  Fly   485 KCSWGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPAS 549
            :.:||      :|...::..:.:.:..:..||.   ...:|...:|...:..|. .|.:.....|
pombe   363 RLAWG------HNTLPVSALSQSQSQVSDEGFD---RTLSANQIFGMNQSVIGA-NSGSSNSSGS 417

  Fly   550 SATAAAVTP-AAASAAAVQNQFLQGIQGYHFGQYGGYQQGYMGMGVQIPATWQGVTQAQISPAQ- 612
            |..:|.|:| .||:.:.:.|..:..|.|.:...:.......:.....|..|..| :.:.::|..
pombe   418 SLKSAPVSPRTAAAQSLLPNSVVSSINGMNSVNFSTISPPPLSRSASISPTLSG-SGSGLTPLSS 481

  Fly   613 ---QLATG-VAGTAIPQAAGVVAYPIQ-QFQVSPQV 643
               ..||| |.|...||::.:.:..|. ..:|.|.|
pombe   482 HFPSAATGLVGGQVYPQSSVLQSSKINGSAKVQPSV 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	25/77 (32%)
trv	NP_001163754.3	RRM3_TIA1_like	416..491	CDD:240800	28/74 (38%)
csx1	NP_594243.1	RRM	67..367	CDD:223796	62/198 (31%)
		RRM1_NGR1_NAM8_like	86..168	CDD:241055
		RRM2_NGR1_NAM8_like	181..260	CDD:241057	26/81 (32%)
		half-pint	<217..>577	CDD:130706	85/322 (26%)
		RRM3_NGR1_NAM8_like	296..367	CDD:240792	27/73 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	112	1.000	Inparanoid score	I1562
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960