Protein Alignment trv and Tia1

DIOPT Version :9

• Sequence 1: NP_001163754.3
• Gene: trv / 43362
• FlyBaseID: FBgn0085391
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_035715.1
• Gene: Tia1 / 21841
• MGIID: 107914
• Length: 386
• Species: Mus musculus
• Alignment Length: 409
• Identity: 165/409 - (40%)
• Similarity: 209/409 - (51%)
• Gaps: 91/409 - (22%)

  Fly   237 AAAAVSAYQRNGKLPRNLPALRAMEMALRTNSFATPPAPHSLPLPPPHAARTEGGGQDMEDSDEE 301
            ||||::|  .||:        :.|...::.| :||.|:                 .|..:.|...
Mouse    59 AAAALAA--MNGR--------KIMGKEVKVN-WATTPS-----------------SQKKDTSSST 95

  Fly   302 MEYMPPLHKQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEA 366
            :.........||:||||||.||.|:.::.||.|||.|||.|||:|..|.||||||||||..|.:|
Mouse    96 VVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDA 160

  Fly   367 ESAITAMNGQWLGSRSIRTNWATRKPPASK----ENIKPLTFDEVYNQSSPSNCTVYVGGVNSAL 427
            |:||..|.|||||.|.||||||||||||.|    .|.|.|::|||.:||||:|||||.|||.|.|
Mouse   161 ENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGL 225

  Fly   428 TALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKES 492
            |   |:::::||:|:|.|.|||||.||||:|||||:.|:|.||||.|:.|.|....|||.||||:
Mouse   226 T---EQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKET 287

  Fly   493 GDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVT 557
            .|..|    ..|..|.     .|:|         ..|||    .|.||
Mouse   288 LDMIN----PVQQQNQ-----IGYP---------PTYGQ----WGQWY----------------- 313

  Fly   558 PAAASAAAVQNQFLQGIQGYHFGQYGGYQQGYMGMG---VQIPATWQGVTQAQISPAQQLATGVA 619
               .:|..: .|::.  .|:....||.|.|.:...|   .|..|.|.|...: :.|.|    |..
Mouse   314 ---GNAQQI-GQYVP--NGWQVPAYGVYGQPWSQQGFNQTQSSAPWMGPNYS-VPPPQ----GQN 367

  Fly   620 GTAIP-QAAG--VVAYPIQ 635
            |:.:| |.||  |..|..|
Mouse   368 GSMLPSQPAGYRVAGYETQ 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:240799	48/73 (66%)
		RRM3_TIA1_like	416..491	CDD:240800	44/74 (59%)
Tia1	NP_035715.1	ELAV_HUD_SF	6..280	CDD:273741	123/251 (49%)
		RRM1_TIA1	8..81	CDD:241059	9/32 (28%)
		RRM2_TIA1	105..184	CDD:241062	52/78 (67%)
		RRM3_TIA1	214..287	CDD:241065	45/75 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..376		7/25 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I7056
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000924
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X831
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.010