Protein Alignment betaTub97EF and TUBA1C

DIOPT Version :9

• Sequence 1: NP_001163753.1
• Gene: betaTub97EF / 43359
• FlyBaseID: FBgn0003890
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001290043.1
• Gene: TUBA1C / 84790
• HGNCID: 20768
• Length: 519
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 182/456 - (39%)
• Similarity: 273/456 - (59%)
• Gaps: 19/456 - (4%)

  Fly     2 REIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESAL--QHERIDVYYNEASSGKYVPRAV 64
            ||.:.:..||.|.|||:..||:...||||.|:|....:..:  ..:..:.:::|..:||:|||||
Human    72 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAV 136

  Fly    65 LIDLEPGTMDSVRQSPVGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCDC 129
            .:||||..:|.||.....|||.|:..:.|:..|.||:|:||||.|.|:||.||:.:||.::.|..
Human   137 FVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTG 201

  Fly   130 LQGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSDTVVEPYNATLSIHQLVE 194
            ||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|..:|
Human   202 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLE 266

  Fly   195 NTDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMVP 259
            ::|..|.:||||:||||.|.|.:..|||.:||.|:|..:|.:|..|||.|.||.||.:...|:||
Human   267 HSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVP 331

  Fly   260 FPRLHFFMPGFAPLTAKGSQQYRALTVAELTQQMFDAKNMMTACDPRHGRYLTVACIFRGPMSMK 324
            :||:||.:..:||:.:.....:..|||||:|...|:..|.|..||||||:|:....::||.:..|
Human   332 YPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPK 396

  Fly   325 EVDTQMYNVQSKNSSYFVEWIPNNVKVAVCDIPP--------RGLKMSATFIGNSTAIQEIFKRI 381
            :|:..:..:::|.:..||:|.|...||.:...||        ..::.:...:.|:||:.|.:.|:
Human   397 DVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARL 461

  Fly   382 SEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQEATADDEVEFDDEQAEQEGY 446
            ..:|..|:.::||:|||.||||:|.||:||..:|..|..:|         :||..|....|.||.
Human   462 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY---------EEVGADSADGEDEGE 517

  Fly   447 E 447
            |
Human   518 E 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	179/451 (40%)
		beta_tubulin	2..426	CDD:276956	175/433 (40%)
TUBA1C	NP_001290043.1	PTZ00335	72..518	CDD:185562	181/454 (40%)
		alpha_tubulin	72..505	CDD:276955	175/441 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910