DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub97EF and TUB1

DIOPT Version :9

Sequence 1:	NP_001163753.1	Gene:	betaTub97EF / 43359	FlyBaseID:	FBgn0003890	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_177706.1	Gene:	TUB1 / 843911	AraportID:	AT1G75780	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	449	Identity:	358/449 - (79%)
Similarity:	411/449 - (91%)	Gaps:	3/449 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESA-LQHERIDVYYNEASSGKYVPRAV 64
            ||||:|:|.|||||||||||||:|.||||:||.|.|:|:|| ||.|||:|||||||.|:||||||
plant     1 MREILHVQGGQCGNQIGSKFWEVICDEHGVDPTGRYNGDSADLQLERINVYYNEASGGRYVPRAV 65

  Fly    65 LIDLEPGTMDSVRQSPVGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCDC 129
            |:|||||||||:|..|.||:|||||||:||||||||||||||||||||||:||:|:|||:|.|||
plant    66 LMDLEPGTMDSIRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDAVLDVVRKEAENCDC 130

  Fly   130 LQGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSDTVVEPYNATLSIHQLVE 194
            |||||:.||||||||||:|||||||||||||||:|.:|||.||||||||||||||||||:|||||
plant   131 LQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVE 195

  Fly   195 NTDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMVP 259
            |.||...:||||||||||||||||:|::||||||:|.||||||..||||||||:||||||||::|
plant   196 NADECMVLDNEALYDICFRTLKLSTPSFGDLNHLISATMSGVTCSLRFPGQLNSDLRKLAVNLIP 260

  Fly   260 FPRLHFFMPGFAPLTAKGSQQYRALTVAELTQQMFDAKNMMTACDPRHGRYLTVACIFRGPMSMK 324
            ||||||||.||||||::|||||.:|||.||||||:||||||.|.|||||||||.:.:|||.||.|
plant   261 FPRLHFFMVGFAPLTSRGSQQYISLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTK 325

  Fly   325 EVDTQMYNVQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSATFIGNSTAIQEIFKRISEQFTAMF 389
            |||.|:.|||:|||||||||||||||.:||||||.|:||::||:||||:|||:|:|:||||||||
plant   326 EVDEQILNVQNKNSSYFVEWIPNNVKSSVCDIPPTGIKMASTFVGNSTSIQEMFRRVSEQFTAMF 390

  Fly   390 RRKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQEATADDEVEFDDEQAEQEGYES 448
            |||||||||||||||||||||||||||||:|||||||:||||:|.|:|:|  |::.|||
plant   391 RRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEDEYDEE--EEQVYES 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	355/443 (80%)
betaTub97EF	NP_001163753.1	beta_tubulin	2..426	CDD:276956	343/424 (81%)
TUB1	NP_177706.1	PLN00220	1..431	CDD:215107	347/429 (81%)
TUB1	NP_177706.1	beta_tubulin	2..427	CDD:276956	343/424 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	385	1.000	Domainoid score	I157
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	798	1.000	Inparanoid score	I89
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	1	1.000	-	-		mtm983
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.980