Protein Alignment betaTub97EF and TUBA1A

DIOPT Version :9

• Sequence 1: NP_001163753.1
• Gene: betaTub97EF / 43359
• FlyBaseID: FBgn0003890
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001257328.1
• Gene: TUBA1A / 7846
• HGNCID: 20766
• Length: 451
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 183/457 - (40%)
• Similarity: 275/457 - (60%)
• Gaps: 17/457 - (3%)

  Fly     1 MREIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESAL--QHERIDVYYNEASSGKYVPRA 63
            |||.:.:..||.|.|||:..||:...||||.|:|....:..:  ..:..:.:::|..:||:||||
Human     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRA 65

  Fly    64 VLIDLEPGTMDSVRQSPVGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCD 128
            |.:||||..:|.||.....|||.|:..:.|:..|.||:|:||||.|.|:||.||:.:||.::.|.
Human    66 VFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCT 130

  Fly   129 CLQGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSDTVVEPYNATLSIHQLV 193
            .||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|..:
Human   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   194 ENTDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMV 258
            |::|..|.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:...|:|
Human   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   259 PFPRLHFFMPGFAPLTAKGSQQYRALTVAELTQQMFDAKNMMTACDPRHGRYLTVACIFRGPMSM 323
            |:||:||.:..:||:.:.....:..|:|||:|...|:..|.|..||||||:|:....::||.:..
Human   261 PYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVP 325

  Fly   324 KEVDTQMYNVQSKNSSYFVEWIPNNVKVAVCDIPP--------RGLKMSATFIGNSTAIQEIFKR 380
            |:|:..:..:::|.:..||:|.|...||.:...||        ..::.:...:.|:|||.|.:.|
Human   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

  Fly   381 ISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQEATADDEVEFDDEQAEQEG 445
            :..:|..|:.::||:|||.||||:|.||:||..:|..|..:|    |....|.||   .:.|:||
Human   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY----EEVGVDSVE---GEGEEEG 448

  Fly   446 YE 447
            .|
Human   449 EE 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	180/452 (40%)
		beta_tubulin	2..426	CDD:276956	174/433 (40%)
TUBA1A	NP_001257328.1	PTZ00335	1..440	CDD:185562	177/442 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		9/26 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910