Protein Alignment betaTub97EF and TUBG1

DIOPT Version :9

• Sequence 1: NP_001163753.1
• Gene: betaTub97EF / 43359
• FlyBaseID: FBgn0003890
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: XP_024306672.1
• Gene: TUBG1 / 7283
• HGNCID: 12417
• Length: 538
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 159/540 - (29%)
• Similarity: 265/540 - (49%)
• Gaps: 106/540 - (19%)

  Fly     2 REIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESALQHERIDVYYNEASSGKYVPRAVLI 66
            |||:.||.||||||||.:||:.:..||||.|.|.....:....:|.||::.:|....|:|||||:
Human     3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLL 67

  Fly    67 DLEPGTMDSVRQSPVGQLFRPDNFVYGQ--SGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCDC 129
            ||||..:.|:..||..:|:.|:|....:  .|||||||.| :::|.::.:.:.:::.:|::|.|.
Human    68 DLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDIIDREADGSDS 131

  Fly   130 LQGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPS-PKVSDTVVEPYNATLSIHQLV 193
            |:||.|.||:.||||||||:.|:.::.:.||.:::.::||.|: .::||.||:|||:.|::.:|.
Human   132 LEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLT 196

  Fly   194 ENTDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMV 258
            :|.|....:||.||..|....|.:.:|::..:|.|||..||..||.||:||.:|.||..|..:::
Human   197 QNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLI 261

  Fly   259 PFPRLHFFMPGFAPLTA------------------------------------------------ 275
            |.|||||.|.|:.|||.
Human   262 PTPRLHFLMTGYTPLTTDQSVRAAFSVPGQAGPGPNRPCPSLSLFPTAPGATLCGPQGAALRDWH 326

  Fly   276 ------------------------KG-----------SQQY-----RALTVAELTQQMFDAKNMM 300
                                    ||           |..|     |..||.::.:::...||:|
Human   327 RVGDFLADLLSTLPLPLASAKEKPKGDCALSAGRVPVSLSYQVASVRKTTVLDVMRRLLQPKNVM 391

  Fly   301 TACDPRHGR-------YLTVACIFRGPMSMKEVDTQMYNVQSKNSSYFVEWIPNNVKVAV---CD 355
            .:.    ||       |:.:..|.:|.:...:|...:..::.:..:.|:.|.|.:::||:   ..
Human   392 VST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSP 452

  Fly   356 IPPRGLKMSATFIGNSTAIQEIFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLIS 420
            ..|...::|...:.|.|:|..:|:|...|:..:.:|:|||..:..|.|.:..|.|.:::...:..
Human   453 YLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQ 517

  Fly   421 EYQQYQEATADDEVEFDDEQ 440
            ...:|..||..|.:.:..::
Human   518 LIDEYHAATRPDYISWGTQE 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	159/540 (29%)
		beta_tubulin	2..426	CDD:276956	155/524 (30%)
TUBG1	XP_024306672.1	gamma_tubulin	3..522	CDD:276957	155/523 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910