Protein Alignment betaTub97EF and TUBB2A

DIOPT Version :9

• Sequence 1: NP_001163753.1
• Gene: betaTub97EF / 43359
• FlyBaseID: FBgn0003890
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001060.1
• Gene: TUBB2A / 7280
• HGNCID: 12412
• Length: 445
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 389/444 - (87%)
• Similarity: 421/444 - (94%)
• Gaps: 0/444 - (0%)

  Fly     1 MREIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESALQHERIDVYYNEASSGKYVPRAVL 65
            ||||||:||||||||||:||||:|||||||||.|.|||:|.||.|||:||||||:..||||||:|
Human     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAIL 65

  Fly    66 IDLEPGTMDSVRQSPVGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCDCL 130
            :|||||||||||..|.||:|||||||:||||||||||||||||||||:||||:|:|||||.||||
Human    66 VDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCL 130

  Fly   131 QGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSDTVVEPYNATLSIHQLVEN 195
            |||||.||||||||||:||||||||||||||||||:|||:||||||||||||||||||:||||||
Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVEN 195

  Fly   196 TDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMVPF 260
            ||||:.||||||||||||||||::|||||||||||.|||||||||||||||||||||||||||||
Human   196 TDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 260

  Fly   261 PRLHFFMPGFAPLTAKGSQQYRALTVAELTQQMFDAKNMMTACDPRHGRYLTVACIFRGPMSMKE 325
            ||||||||||||||::||||||||||.||||||||:||||.|||||||||||||.||||.|||||
Human   261 PRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKE 325

  Fly   326 VDTQMYNVQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSATFIGNSTAIQEIFKRISEQFTAMFR 390
            ||.||.|||:|||||||||||||||.|||||||||||||||||||||||||:|||||||||||||
Human   326 VDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFR 390

  Fly   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQEATADDEVEFDDEQAEQE 444
            ||||||||||||||||||||||||||||:|||||||:||||::.||::|:.|.|
Human   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDE 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	388/442 (88%)
		beta_tubulin	2..426	CDD:276956	377/423 (89%)
TUBB2A	NP_001060.1	PLN00220	1..430	CDD:215107	381/428 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..445		14/23 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134314
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S30
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.780