DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub97EF and tubd1

DIOPT Version :9

Sequence 1:	NP_001163753.1	Gene:	betaTub97EF / 43359	FlyBaseID:	FBgn0003890	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001006747.1	Gene:	tubd1 / 448419	XenbaseID:	XB-GENE-488049	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	471	Identity:	122/471 - (25%)
Similarity:	205/471 - (43%)	Gaps:	77/471 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IVHLQAGQCGNQIGSKFWEII-SDEHGIDP-------NGYYHGESALQHERIDVYYNEASSGKYV 60
            :|.:|.||||||:|.:|::|: ||.|. .|       |.||......|      :::|...|..|
Frog     3 VVTVQLGQCGNQVGYEFFDILCSDLHS-KPGHSTKRENDYYQTVCKEQ------FFHEEECGDLV 60

  Fly    61 PRAVLIDLEPGTMDSVRQSPVGQLFRPDNFVYG-------QSGAGNNWAKGHYTEGAELIDSVLE 118
            .||||:|:||    .|....:....|...:.|.       :.|.|||||.|:...|.:..|.|::
Frog    61 TRAVLVDMEP----KVVSKTLSMAGRSGKWKYDISSQFSQKQGCGNNWANGYCVHGPKHQDIVMD 121

  Fly   119 VLRKESEGCDCLQGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSDTVVEPY 183
            ::||:.|.||.|.||....|:.||||||:||.|...:|:.|||.::.:..:.|. ...:.:|:.|
Frog   122 LVRKQVEKCDRLGGFFTIMSMAGGTGSGMGTFLTRCLRDAYPDSLLLNQVIWPY-GTGEVIVQNY 185

  Fly   184 NATLSIHQLVENTDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTT---------- 238
            |:.|::..|..::|.....:|:.::.:|.:.:.:...::.|:|.:::..:..:..
Frog   186 NSILTLSHLYRSSDALLVHENDIIHKVCSQLMNIKQISFRDVNKVIAHQLGSIFQPVYTSEEALH 250

  Fly   239 -CLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAKGSQQYRALT---VAELTQQMFDAKNM 299
             | |.|      |.:|...:||.|..........|..::.|..|....   :.:..:||..|...
Frog   251 YC-RNP------LGELMECLVPHPEYKMLGLRNIPQMSEHSLAYSTFNWNGLLKHLRQMLIANAK 308

  Fly   300 MTACDPRHGR------------------YLTVA--CIFRGPMSMKEVDTQMYNVQS-KNSSYFVE 343
            |......|.|                  ..:||  .|.||.      |.|..:::. ::...:..
Frog   309 MEEGINWHVRPPSQPTAEKTSLRKELQFNTSVANLAILRGK------DVQTASLEGFRDPPLYTP 367

  Fly   344 WIPNNVKVAVCDIPP--RGLKMSATFIGNSTAIQEIFKRISEQFTAMFRRKAFLHWYTGEGMDEM 406
            |:..:....:...|.  ...:.|||.:.||..:.:....|..:...||..||::|.||..|:||.
Frog   368 WLSPDDAFTLWKTPRAFNKYEKSATLVSNSQFLLKPLDNIVGKAWNMFASKAYVHQYTKFGIDEE 432

  Fly   407 EFTEAESNMNDLISEY 422
            ||.|..:.:..:|:.|
Frog   433 EFLETFTTLEQIIASY 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	122/471 (26%)
betaTub97EF	NP_001163753.1	beta_tubulin	2..426	CDD:276956	122/471 (26%)
tubd1	NP_001006747.1	delta_zeta_tubulin-like	2..450	CDD:276958	122/471 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910