Protein Alignment betaTub97EF and TUBA3D

DIOPT Version :9

• Sequence 1: NP_001163753.1
• Gene: betaTub97EF / 43359
• FlyBaseID: FBgn0003890
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_525125.2
• Gene: TUBA3D / 113457
• HGNCID: 24071
• Length: 450
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 178/453 - (39%)
• Similarity: 274/453 - (60%)
• Gaps: 14/453 - (3%)

  Fly     1 MREIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESAL--QHERIDVYYNEASSGKYVPRA 63
            |||.:.:..||.|.|||:..||:...||||.|:|....:..:  ..:..:.:::|..:||:||||
Human     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRA 65

  Fly    64 VLIDLEPGTMDSVRQSPVGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCD 128
            |.:||||..:|.||.....|||.|:..:.|:..|.||:|:||||.|.|::|.||:.:||.::.|.
Human    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCT 130

  Fly   129 CLQGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSDTVVEPYNATLSIHQLV 193
            .||||.:.||.|||||||..:||:.::..:|..:....|::.|:|:||..||||||:.|:.|..:
Human   131 GLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   194 ENTDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMV 258
            |::|..|.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:...|:|
Human   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   259 PFPRLHFFMPGFAPLTAKGSQQYRALTVAELTQQMFDAKNMMTACDPRHGRYLTVACIFRGPMSM 323
            |:||:||.:..:||:.:.....:..|:|||:|...|:..|.|..||||||:|:....::||.:..
Human   261 PYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVP 325

  Fly   324 KEVDTQMYNVQSKNSSYFVEWIPNNVKVAVCDIPP--------RGLKMSATFIGNSTAIQEIFKR 380
            |:|:..:..:::|.:..||:|.|...||.:...||        ..::.:...:.|:|||.|.:.|
Human   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

  Fly   381 ISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQEATADDEVEFDDEQAEQ 443
            :..:|..|:.::||:|||.||||:|.||:||..::..|..:|    |....|.||.:.|:.|:
Human   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDY----EEVGVDSVEAEAEEGEE 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	178/453 (39%)
		beta_tubulin	2..426	CDD:276956	171/433 (39%)
TUBA3D	NP_525125.2	PTZ00335	1..440	CDD:185562	174/442 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910