Protein Alignment CG4849 and RIA1

DIOPT Version :9

• Sequence 1: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_014236.1
• Gene: RIA1 / 855558
• SGDID: S000005107
• Length: 1110
• Species: Saccharomyces cerevisiae
• Alignment Length: 1132
• Identity: 260/1132 - (22%)
• Similarity: 462/1132 - (40%)
• Gaps: 321/1132 - (28%)

  Fly   124 LMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEER---QLRYTDTLFTEQERGCSIKA 185
            |.:.|..|||:.:|.|:.||||:..|.|:...    ..:.:|   ::|:.|....||.||.::::
Yeast    12 LQNDPSCIRNICIVAHVDHGKTSLSDSLLASN----GIISQRLAGKIRFLDARPDEQLRGITMES 72

  Fly   186 TPVTLVLQDVKQK---------SYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNT 241
            :.::|..:.::::         .:|:|:.|:|||::||.|.:||.|:.||.|:.:|..|||...|
Yeast    73 SAISLYFRVLRKQEGSDEPLVSEHLVNLIDSPGHIDFSSEVSAASRLCDGAVVLVDVVEGVCSQT 137

  Fly   242 ERLLKHAVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGA---------- 296
            ..:|:....|:....:.:|||||||.||:|.||:||..|..::|:||.::.::.|
Yeast   138 VTVLRQCWTEKLKPILVLNKIDRLITELQLTPQEAYIHLSKVIEQVNSVIGSFFANERQLDDLFW 202

  Fly   297 ---------------PDDNLLVSPILGNVCFASSLYGFCFTLKSFAKLYADTYEGVAYLDFAKRL 346
                           .|..:..:|...||.|||::.|:.|.:...||.|.... |....:..|.|
Yeast   203 REQLEKNENAEYIEKDDSGIYFNPTDNNVIFASAIDGWGFNIGQLAKFYEQKL-GAKRENLQKVL 266

  Fly   347 WGDMYFNSKTRKF--SKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLAE-LNVRVSK 408
            |||.|.:.||:|.  :|.....|.:..|...|||.::|:...::...|:.:.:.:|: ||:::..
Yeast   267 WGDFYMDPKTKKIINNKGLKGRSLKPLFTSLILENIWKIYQNIITSRDSEMVEKIAKTLNIKLLA 331

  Fly   409 EEMKS-NIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIY-----TGPKEGDIYRD 467
            .:::| :.:.|||.:..:::...:..:...:|.:.||||:...:::.|.     |...:..:.:.
Yeast   332 RDLRSKDDKQLLRTIMGQWLPVSTAVLLTVIEKLPSPLESQTDRLNTILVSESDTAAMDPRLLKA 396

  Fly   468 MISCNQYGTLMVHSSKMY----------------------------------------------- 485
            |.:|::.|.:..:.|||.
Yeast   397 MKTCDKEGPVSAYVSKMLSIPREELPVESKRIASSDELMERSRKAREEALNAAKHAGMVENMAMM 461

  Fly   486 ----------------------------------------------------------------- 485
                                                                             
Yeast   462 DLNDNSKNTSDLYKRAKDTVMTPEVGEQTKPKPSRNNDVFCVVSEPSSALDLEFEYEGEDDSDSQ 526

  Fly   486 -------------PND-------------------------------------DCTFFQVLARIV 500
                         |||                                     :|  ....|||.
Yeast   527 DNFGLDFVPTDIDPNDPLSSMFEYEEEDPLLESIKQISEDVNDEVDDIFDEKEEC--LVAFARIY 589

  Fly   501 SGTLHAGQEVRVLGENYTLQ-DEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVK 564
            ||||..|||:.|||..|..: .||......:..|::|..:..|.|:..|:||.|.|.|:...::|
Yeast   590 SGTLRVGQEISVLGPKYDPKCPEEHIETAIITHLYLFMGKELVPLDVCPSGNIVGIRGLAGKVLK 654

  Fly   565 TSTIVD-----INVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRV 624
            :.|:::     :|:....:.|.|       |:::||||.||.|:.|::.||:.::::.|.:.|.|
Yeast   655 SGTLIEKGVQGVNLAGVNFHFTP-------IVRVAVEPANPVEMSKLVRGLKLLDQADPCVHTYV 712

  Fly   625 EESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSL---------KCFAE 680
            |.:|||::...|||:|:..:.||.:.::.|:|..::|.:.:.||.:..|.:         :...|
Yeast   713 ENTGEHILCTAGELHLERCLKDLTERFAGIEITHSEPAIPYRETFLSASDMNPPQNSQLGRGVHE 777

  Fly   681 TPNKKNKITMISEPL-----------EKGLAEDIENGTVCIN----------WNKKRIGEFFQ-- 722
            ....:.|||..:.||           :..:...::..|..::          .:||.:...|:
Yeast   778 LLLSQYKITFRTFPLSGKVTDFLSQHQNSIKNILKTSTSSMDPVIESTGSSFLDKKSLLVAFEEV 842

  Fly   723 VNYD---WDLLAARSI--WAFGPDSTGPNILVDDTLPSEVDKNLLTAV----------KDSIVQG 772
            :|.:   .:||:...:  ..|||...|.|||:.       ..|||.::          .|||..|
Yeast   843 INQEEKSRELLSGFKVKLAGFGPSRVGCNILLS-------QDNLLGSLFEGTPAAFEYSDSIKNG 900

  Fly   773 FQWGTREGPLCEEPIRNVKFKILDGVIANEALHRG--------------------GGQIIPTARR 817
            ||....||||..||::.:       .:..|::|:.                    .|::|.:.|.
Yeast   901 FQLAVSEGPLANEPVQGM-------CVLVESVHKMSQDEIESIEDPRYQQHIVDLSGRLITSTRD 958

  Fly   818 VAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFIPAID 882
            ..:.|||..:||:|......::|...|.:..||.|:.:|.|.:..:....|:|.:.|:|.:|.::
Yeast   959 AIHEAFLDWSPRIMWAIYSCDIQTSVDVLGKVYAVILQRHGKIISEEMKEGTPFFQIEAHVPVVE 1023

  Fly   883 SFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLE----PQQASHLAREFMIKTRRR 943
            :||...|:|..|.|.|....||..::.:..||.........||    .....::||:.|...|||
Yeast  1024 AFGLSEDIRKRTSGAAQPQLVFSGFECIDLDPFWVPTTEEELEELGDTADRENIARKHMNAIRRR 1088

  Fly   944 KGLSEDVSINKFFDDPMLLELARQDVL 970
            |||        |.::.::....:|..|
Yeast  1089 KGL--------FIEEKVVENAEKQRTL 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:292623
		PTZ00416	115..957	CDD:240409	258/1117 (23%)
		Snu114p	132..340	CDD:206730	72/244 (30%)
		Translation_Factor_II_like	477..568	CDD:295476	34/253 (13%)
		snRNP_III	589..660	CDD:293921	26/70 (37%)
		EF2_IV_snRNP	660..837	CDD:238840	50/243 (21%)
		eEF2_C_snRNP	832..911	CDD:239765	21/78 (27%)
RIA1	NP_014236.1	FusA	1..1091	CDD:357662	255/1106 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810