DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4849 and AT3G22980

DIOPT Version :9

Sequence 1:	NP_651605.1	Gene:	CG4849 / 43358	FlyBaseID:	FBgn0039566	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001319621.1	Gene:	AT3G22980 / 821872	AraportID:	AT3G22980	Length:	1015	Species:	Arabidopsis thaliana

Alignment Length:	1024	Identity:	270/1024 - (26%)
Similarity:	456/1024 - (44%)	Gaps:	227/1024 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 IRNVALVGHLHHGKTTFVDCLIRQT-----HPQFETMEERQLRYTDTLFTEQERGCSIKATPVTL 190
            :||:.::.|:.|||||..|.||..:     ||:.    ..:||:.|.|..||.|..::|::.::|
plant     9 VRNICILAHVDHGKTTLADHLIASSGGGVLHPRL----AGKLRFMDYLDEEQRRAITMKSSSISL 69

  Fly   191 VLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAI 255
                 |.|.|.||:.|:|||::|..|.:.|.|:|||.::.:||.|||.:.|..:|:.|..|:...
plant    70 -----KYKDYSLNLIDSPGHMDFCSEVSTAARLSDGALVLVDAVEGVHIQTHAVLRQAWIEKLTP 129

  Fly   256 TVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPD-----DNLLVSP---------- 305
            .:.:|||||||.||:|.|.:||.:|..||.||||::|.|.:..     |::|.||
plant   130 CLVLNKIDRLIFELRLSPMEAYTRLIRIVHEVNGIVSAYKSEKYLSDVDSILASPSGELSAESLE 194

  Fly   306 IL------------GNVCFASSLYGFCFTLKSFAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRK 358
            :|            |||.|..:|.|:.|.:..||..||... |.:.....|.|||..|:..||:.
plant   195 LLEDDEEVTFQPQKGNVVFVCALDGWGFGIAEFANFYASKL-GASATALQKSLWGPRYYIPKTKM 258

  Fly   359 FSKKQ---PHNSAQRSFVEFILEPMYKLIAQVV--GDVDTTLSDTLAELNVRVSKEEMKS-NIRP 417
            ...|:   ..:.|:..||:|:|||::::....:  |.....|...:...|:.:...|::: :.:.
plant   259 IVGKKNLSAGSKAKPMFVQFVLEPLWQVYEAALDPGGDKAVLEKVIKSFNLSIPPRELQNKDPKN 323

  Fly   418 LLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIYTGPK-------------EGDIYRDMI 469
            :|:.|.:|::......:.|.|:|:..|:.....::..:....|             |.::.|..|
plant   324 VLQSVMSRWLPLSDAVLSMAVKHLPDPIAAQAYRIPRLVPERKIIGGDDVDSSVLAEAELVRKSI 388

  Fly   470 -SCNQY--GTLMVHSSKMY---------------------------PNDDCTFFQVLARIVSGTL 504
             :|:..  ...:|..|||:                           .:|:|  |...|||.||.|
plant   389 EACDSSSDSPCVVFVSKMFAIPMKMIPQDGNHRERMNGLNDDDSKSESDEC--FLAFARIFSGVL 451

  Fly   505 HAGQEVRVLGENY-TLQDEEDSRILQ---VGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKT 565
            .|||.|.|:...| .|:.|...:.:|   :..|::...:....:..|.|||.|.|.|:...|.|:
plant   452 RAGQRVFVITALYDPLKGESSHKYIQEAELHSLYLMMGQGLTPVTEVKAGNVVAIRGLGPYISKS 516

  Fly   566 STIVDINVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEH 630
            :|   ::...:.:....::|.....:::|:||.:|:::..::.|||.:|::.|.:...|...|||
plant   517 AT---LSSTRNCWPLASMEFQVSPTLRVAIEPSDPADMSALMKGLRLLNRADPFVEITVSARGEH 578

  Fly   631 VILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVE-----TSSLKCFA---------ET 681
            |:...||::|:..:.||::.:::::::|:.|:|::.||:..     ..||:..:         .|
plant   579 VLAAAGEVHLERCVKDLKERFAKVNLEVSPPLVSYRETIEGDGSNLLESLRSLSLNSSDYIEKRT 643

  Fly   682 PNKKNKITM----ISEPLEKGLAEDIE-----------NGTVCINWNKKRIGEFFQVNYD----- 726
            ||.:..|.:    :...|.|.|.|:.|           :....:...|..:||    |.|
plant   644 PNGRCIIRVHVMKLPHALTKLLDENTELLGDIIGGKGSHSVKILESQKPSLGE----NVDPIEEL 704

  Fly   727 -------------------------WDLLAARSIWAFGPDSTGPNILV----------------- 749
                                     |..|..| |||.||...|||||.
plant   705 KKQLVEAGVSSSSETEKDREKCKTEWSKLLKR-IWALGPREKGPNILFAPDGKRIAEDGSMLVRG 768

  Fly   750 ------------DDT-LPSEVDKNLL----TAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDG 797
                        |.| .|:||.:..|    ..::.|||.|||..|..||||:||:..:.|.|...
plant   769 SPHVSQRLGFTEDSTETPAEVSETALYSEALTLESSIVSGFQLATASGPLCDEPMWGLAFTIESH 833

  Fly   798 VIANEALHRG--------GGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLA 854
            :...|.:...        .||::...:....:|.|...||::|...|.|:....:.:..:|.||:
plant   834 LAPAEDVETDKPENFGIFTGQVMTAVKDACRAAVLQTNPRIVEAMYFCELNTAPEYLGPMYAVLS 898

  Fly   855 RRRGHVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPL---- 915
            |||..:.::....||.::|:.|::|..:||||..:||..|.|.|..|.|..||:::..||.
plant   899 RRRARILKEEMQEGSSLFTVHAYVPVSESFGFADELRKGTSGGASALMVLSHWEMLEEDPFFVPK 963

  Fly   916 ---------DKSIIIRPLEPQQASHLAREFMIKTRRRKGLSEDVSINKF 955
                     |.:.::        .:.||:.:...||||||..:..:.::
plant   964 TEEEIEEFGDGASVL--------PNTARKLINAVRRRKGLHVEEKVVQY 1004

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:292623
		PTZ00416	115..957	CDD:240409	270/1024 (26%)
		Snu114p	132..340	CDD:206730	86/239 (36%)
		Translation_Factor_II_like	477..568	CDD:295476	32/121 (26%)
		snRNP_III	589..660	CDD:293921	20/70 (29%)
		EF2_IV_snRNP	660..837	CDD:238840	62/277 (22%)
		eEF2_C_snRNP	832..911	CDD:239765	27/78 (35%)
AT3G22980	NP_001319621.1	FusA	1..998	CDD:357662	270/1016 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820