DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4849 and eftud2

DIOPT Version :9

Sequence 1:	NP_651605.1	Gene:	CG4849 / 43358	FlyBaseID:	FBgn0039566	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001025537.1	Gene:	eftud2 / 594937	XenbaseID:	XB-GENE-972643	Length:	974	Species:	Xenopus tropicalis

Alignment Length:	975	Identity:	733/975 - (75%)
Similarity:	835/975 - (85%)	Gaps:	1/975 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDSDLYDEFGNYIGPDLDSDEEDEQSIYGQPDVQDDPEDAMDEDEVEPQEDEDKEVTAVVLHEDK 65
            ||:||||||||||||:||||::::....|:.|...|..:..|:||.....|:|:....|||||||
Frog     1 MDADLYDEFGNYIGPELDSDDDNDDDDMGRDDRDVDVAEDEDDDEYTGDPDDDRGGMEVVLHEDK 65

  Fly    66 RYYPSAVEVYGPDVETIVQEEDAQPLDKPLIEPVKKLKFQIKEQDMQETTYDMEFMADLMDTPPL 130
            :|||:|.|:|||:|||||||||.|||.:|:|:|||..||.:.||.:..|.|:|:|:|||||.|.|
Frog    66 KYYPTAEEIYGPEVETIVQEEDTQPLTEPIIKPVKAKKFSMMEQGLPATVYEMDFLADLMDNPEL 130

  Fly   131 IRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCSIKATPVTLVLQDV 195
            ||||.|.||||||||.||||||.||||:.....::.|.|||.||||||||..:|:||||:|:.|.
Frog   131 IRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRHDQDLCYTDILFTEQERGVGMKSTPVTIVVPDT 195

  Fly   196 KQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCIN 260
            |:||||.||.|||||||||||.||..|:|||||||||||||||||||||:|||||||.|:|||||
Frog   196 KEKSYLFNIMDTPGHVNFSDEVTAGFRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCIN 260

  Fly   261 KIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKS 325
            |||||||||||||.|||:||:|||:|||||||.| :.|:||::||:|||||||||.|..||||.|
Frog   261 KIDRLILELKLPPTDAYYKLRHIVDEVNGLLSMY-STDENLILSPLLGNVCFASSQYSICFTLGS 324

  Fly   326 FAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGD 390
            |||:|||||..:.|.:||||||||:|||.|||||:||.|.:|:|||||||:|||:||::||||||
Frog   325 FAKIYADTYGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFVLEPLYKILAQVVGD 389

  Fly   391 VDTTLSDTLAELNVRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHI 455
            |||||..||.||.:.::|||:|.|||||||||||||.|:.:|||||||:||.||...|:.|::|.
Frog   390 VDTTLPQTLEELGIHLTKEELKLNIRPLLRLVCNRFFGEFTGFVDMCVQHIPSPKAGARAKIEHT 454

  Fly   456 YTGPKEGDIYRDMISCNQYGTLMVHSSKMYPNDDCTFFQVLARIVSGTLHAGQEVRVLGENYTLQ 520
            |.|..:.::...|..|:..|.||.|::|||..||...|....|::|||:||||.|:||||||||:
Frog   455 YAGGIDCELGEAMSECDPDGPLMCHTTKMYSTDDGVQFHAFGRLLSGTIHAGQPVKVLGENYTLE 519

  Fly   521 DEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKF 585
            |||||::..||||||..:||.:|:|||||||||||||:||.||||:||.:....|:..|||||||
Frog   520 DEEDSQVCTVGRLWVSVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKF 584

  Fly   586 NTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEHVILGTGELYLDCVMHDLRKM 650
            ||.|:||||||||||||||||||||||||||||.|:|:|||||||||||||||||||||||||||
Frog   585 NTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKM 649

  Fly   651 YSEIDIKVADPVVAFCETVVETSSLKCFAETPNKKNKITMISEPLEKGLAEDIENGTVCINWNKK 715
            |||||||||||||.|||||||||||||||||||||||||||:|||||||||||||..|.|:||:|
Frog   650 YSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQISWNRK 714

  Fly   716 RIGEFFQVNYDWDLLAARSIWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREG 780
            ::|||||..|||||||||||||||||:|||||||||||||||||.||::||||||||||||||||
Frog   715 KLGEFFQTKYDWDLLAARSIWAFGPDTTGPNILVDDTLPSEVDKALLSSVKDSIVQGFQWGTREG 779

  Fly   781 PLCEEPIRNVKFKILDGVIANEALHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADC 845
            |||:|.||||||||||.|||.|.|||||||||||||||.|||||||||||||||.||||||||||
Frog   780 PLCDELIRNVKFKILDAVIAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADC 844

  Fly   846 VSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIV 910
            ||||||||||||||||||||:.|||:||||||||||||||||||||||||||||.||||||||||
Frog   845 VSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIV 909

  Fly   911 PGDPLDKSIIIRPLEPQQASHLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELARQDVLINYPL 975
            |||||||||||||||||.|.||||||||||||||||||||||:||||||||||||:|||::|||:
Frog   910 PGDPLDKSIIIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM 974

Fly 976 975
Frog 975 974

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:292623	60/106 (57%)
		PTZ00416	115..957	CDD:240409	654/841 (78%)
		Snu114p	132..340	CDD:206730	153/207 (74%)
		Translation_Factor_II_like	477..568	CDD:295476	59/90 (66%)
		snRNP_III	589..660	CDD:293921	66/70 (94%)
		EF2_IV_snRNP	660..837	CDD:238840	154/176 (88%)
		eEF2_C_snRNP	832..911	CDD:239765	73/78 (94%)
eftud2	NP_001025537.1	EFTUD2	4..112	CDD:406414	60/107 (56%)
eftud2	NP_001025537.1	FusA	124..956	CDD:357662	649/832 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	369	1.000	Domainoid score	I907
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3133
Inparanoid	1	1.050	1503	1.000	Inparanoid score	I103
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	1	1.000	-	-		FOG0004923
OrthoInspector	1	1.000	-	-		oto104660
Panther	1	1.100	-	-	LDO	PTHR42908
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2958
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160