Protein Alignment CG4849 and efl1

DIOPT Version :9

• Sequence 1: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_697184.5
• Gene: efl1 / 568741
• ZFINID: ZDB-GENE-130103-6
• Length: 1133
• Species: Danio rerio
• Alignment Length: 1084
• Identity: 281/1084 - (25%)
• Similarity: 453/1084 - (41%)
• Gaps: 275/1084 - (25%)

  Fly   131 IRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCSIKATPVTLVLQDV 195
            |||:.::.|:.|||||..|||: .::....:....:|||.|:...||.||.::|::.::|... .
Zfish    37 IRNLCILAHVDHGKTTLADCLV-ASNGIISSRLAGKLRYLDSREDEQIRGITMKSSAISLHFA-T 99

  Fly   196 KQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCIN 260
            ....:|:|:.|:||||:||.|.:.|:|:.||.::.:||.|||...|:.:|:.|..|.....:.||
Zfish   100 GGVEFLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDAVEGVCPQTQVVLRQAWLENIRPVLVIN 164

  Fly   261 KIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTY------------------------------- 294
            ||||||.||||..|:||..|:.|:|:||.:..|.
Zfish   165 KIDRLIAELKLTSQEAYVHLQKILEQVNAVTGTLFTSKVLEERAEKDAGSQSSFTENESGDHVYD 229

  Fly   295 ------GAPDDNLLVSPILGNVCFASSLYGFCFTLKSFAKLYADTYEGVAYLDFAKRLWGDMYFN 353
                  ...|.:|..||..|||.|||::.|:.|::..||::|:... |:......|.||||.|.|
Zfish   230 WSAGLEETDDSDLYFSPDRGNVVFASAIDGWGFSIHQFAEMYSQKM-GIRSSVLLKTLWGDFYLN 293

  Fly   354 SKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVD-TTLSDTLAELNVRVSKEEMK-SNIR 416
            :|.:|..|.......:..||:|||:.::.:...||...| ..:...:..|.::|...::: |:.:
Zfish   294 AKAKKIMKGAQSKGKKPLFVQFILDNIWSMYDAVVTRRDKEKVEKMMTSLGLKVMSRDLRHSDPK 358

  Fly   417 PLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIYT-GPKEGDIYRDM----------IS 470
            .||..:|::::......:.|..|.:.||.|.:..:|:.:.: |.:..|...|.          .|
Zfish   359 VLLSAICSQWLPLSQAVLSMVCEKLPSPAEISAERVEKLMSVGARRFDSLPDKTQELKKAFLDCS 423

  Fly   471 CNQYGTLMVHSSKMYPNDD---------------------------------------------- 489
            .::...::|..|||:..|.
Zfish   424 ADETAPVIVFVSKMFAVDSKALPQNKQRPLTHEEISQRRELARQRHAEKQAANQSAESLASGDAG 488

  Fly   490 ----------------CT-----------------FFQVLARIVSGTLHAGQEVRVLGENY---- 517
                            |.                 .|...||:.||.:..||:|.|||..|
Zfish   489 GDSIPAPAAAGVTDALCAQTEALSVKTTVEEENKEHFVAFARVYSGVVRKGQKVFVLGPKYDPSL 553

  Fly   518 -------------TLQDEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIV 569
                         .|..........|..|::...|...||:.||:||.:.|.|::..|:|::|
Zfish   554 ALRALPEGCSVSDVLPSIPHMSYCTVDSLYLLMGRELEELDEVPSGNVLGIGGLEDVILKSAT-- 616

  Fly   570 DINVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEHVILG 634
             |:.......|.||.|....|:::||||.:|||:||::.|::.:|::.|.....::|:||||::.
Zfish   617 -ISTSPACPPFTPLNFEATPIVRVAVEPKHPSEMPKLVRGMKLLNQADPCAEVLIQETGEHVLVT 680

  Fly   635 TGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFAETPNKKNKITMISEPLEK-- 697
            .||::|...:.|||:.:::|:|..:.|::.|.||||....:....|...|:.|:.:|.:..|:
Zfish   681 AGEVHLQRCLDDLRERFAKIEISSSKPIIPFRETVVRPPRVDMVNEDLGKQQKVAVIHQVKEEQS 745

  Fly   698 -----------GL---------------AEDIENGTVCI---NWNKKRIGEFFQVN--------- 724
                       ||               |..:.....|:   |....|..|.|.::
Zfish   746 KNPECVQVDSSGLVSLTTPNKMATVGVRAIPLPEQVTCLLEDNVELIRTMEQFNLSVREGKTLDI 810

  Fly   725 ---------------------YDWDLLAARSIWAFGPDSTGPNILVDD----TLPS-----EVDK 759
                                 :.| ..|...||||||...|||||::.    ..||     |.:|
Zfish   811 SQKILDNIQDFKVKLESHLQGHKW-RNAVDHIWAFGPRRCGPNILLNSIEGYRRPSVWQCLETEK 874

  Fly   760 NLLTAVKD---SIVQGFQWGTREGPLCEEPIRNVKF-------KILDGVIANEALHRG------- 807
            ...:|::|   ||..|||..|..||:||||:..|.|       ||...|...:::..|
Zfish   875 TESSALRDFDNSIASGFQLATLAGPMCEEPLMGVCFSVESWDMKISTPVAQQDSVDEGSQPAELN 939

  Fly   808 -------------------------------GGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQA 841
                                           .||:|...:.....||.....|||......|:.|
Zfish   940 NEHSEVSPVSSSRSRSKAEAAGSSVDCYGPFSGQLIAAVKEACRYAFQAKPQRLMAAMYTCEIMA 1004

  Fly   842 PADCVSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHH 906
            .|:.:..||.||::|.|.|.|:....|:.::.|||.:|..:||||..::|..|.|.|....:|.|
Zfish  1005 TAEVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLIFSH 1069

  Fly   907 WQIVPGDPL----DKSIIIRPLEPQQASHLAREFMIKTRRRKGL 946
            |:::..||.    .:...:...|...:::.|.::|...|:||||
Zfish  1070 WEVIGSDPFWVPTTEEEYLHFGEKADSTNQALKYMNAVRKRKGL 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:292623
		PTZ00416	115..957	CDD:240409	281/1084 (26%)
		Snu114p	132..340	CDD:206730	81/244 (33%)
		Translation_Factor_II_like	477..568	CDD:295476	32/186 (17%)
		snRNP_III	589..660	CDD:293921	26/70 (37%)
		EF2_IV_snRNP	660..837	CDD:238840	64/294 (22%)
		eEF2_C_snRNP	832..911	CDD:239765	27/78 (35%)
efl1	XP_697184.5	PTZ00416	19..1116	CDD:240409	281/1084 (26%)
		EF2	38..272	CDD:206672	79/235 (34%)
		EF2_II	523..620	CDD:293913	28/99 (28%)
		EF2_snRNP_III	635..706	CDD:293918	26/70 (37%)
		aeEF2_snRNP_like_IV	706..999	CDD:238839	64/293 (22%)
		eEF2_snRNP_like_C	996..1073	CDD:239763	27/76 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920