DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4849 and eIF2gamma

DIOPT Version :9

Sequence 1:	NP_651605.1	Gene:	CG4849 / 43358	FlyBaseID:	FBgn0039566	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001262587.1	Gene:	eIF2gamma / 41843	FlyBaseID:	FBgn0263740	Length:	475	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	53/225 - (23%)
Similarity:	88/225 - (39%)	Gaps:	52/225 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 IKEQDMQETTYDMEFMADLMDTPPLIR-----NVALVGHLHHGKTTFVDCLIRQTHPQFETMEER 165
            :::||:  :..|:..:..|  :|.:|.     |:..:||:.|||:|.|..:......:|:...||
  Fly    14 LQKQDL--SNLDVSKLTPL--SPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELER 74

  Fly   166 ----QLRYTDT-LFTEQERGCSIKATPVTLVLQDVKQKSYLL-----------------NIFDTP 208
                :|.|.:. ::......|...|:.|:    |...|...|                 :..|.|
  Fly    75 NITIKLGYANAKIYKCDNPKCPRPASFVS----DASSKDDSLPCTRLNCSGNFRLVRHVSFVDCP 135

  Fly   209 GHVNFSDEATAAM----RMSDGVVLFIDAAEGV--MLNTERLLKHAVQERQAITVCINKIDRLIL 267
            ||    |...|.|    .:.|..:|.|...|..  ...:|.|....:.:.:.|.:..|||| ||.
  Fly   136 GH----DILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKQILILQNKID-LIK 195

  Fly   268 ELKLPPQDAYFKLKHIVEEVNGLLSTYGAP 297
            |.:...|     .:.|.:.|.|.::. |||
  Fly   196 ESQAKEQ-----YEEITKFVQGTVAE-GAP 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:292623	1/4 (25%)
		PTZ00416	115..957	CDD:240409	51/216 (24%)
		Snu114p	132..340	CDD:206730	47/199 (24%)
		Translation_Factor_II_like	477..568	CDD:295476
		snRNP_III	589..660	CDD:293921
		EF2_IV_snRNP	660..837	CDD:238840
		eEF2_C_snRNP	832..911	CDD:239765
eIF2gamma	NP_001262587.1	PTZ00327	11..465	CDD:240362	53/225 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930