Protein Alignment CG4849 and eftud2

DIOPT Version :10

• Sequence 1: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_956802.2
• Gene: eftud2 / 393480
• ZFINID: ZDB-GENE-040426-1569
• Length: 973
• Species: Danio rerio
• Alignment Length: 975
• Identity: 726/975 - (74%)
• Similarity: 837/975 - (85%)
• Gaps: 2/975 - (0%)

  Fly     1 MDSDLYDEFGNYIGPDLDSDEEDEQSIYGQPDVQDDPEDAMDEDEVEPQEDEDKEVTAVVLHEDK 65
            |::||||||||||||:|||||::|.....: |..:..|:..|:|:.|..||.......|||||||
Zfish     1 METDLYDEFGNYIGPELDSDEDEELDAEDR-DADEADEEGDDDDQAEADEDGGGGGMEVVLHEDK 64

  Fly    66 RYYPSAVEVYGPDVETIVQEEDAQPLDKPLIEPVKKLKFQIKEQDMQETTYDMEFMADLMDTPPL 130
            :|||:|.|||||:|||||||||.|||.:|:|:||:..:|.:.||::..|.|||||:|||||:..|
Zfish    65 KYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVRMKQFTLMEQELPATVYDMEFLADLMDSSEL 129

  Fly   131 IRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCSIKATPVTLVLQDV 195
            ||||.|.||||||||.||||||.||||:....::..|||||.||||||||..||:||||:||.|.
Zfish   130 IRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRDDEDLRYTDILFTEQERGVGIKSTPVTMVLPDS 194

  Fly   196 KQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCIN 260
            :.||||.||.|||||||||||.|:|:|:|||:|||||||||||||||||:|||||||.|||:|||
Zfish   195 RGKSYLFNIMDTPGHVNFSDEVTSAVRLSDGIVLFIDAAEGVMLNTERLIKHAVQERLAITICIN 259

  Fly   261 KIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKS 325
            ||||||:||||||.|||:||:|||:||||||||| :.|::|:|||:|||||||||.|..||||.|
Zfish   260 KIDRLIVELKLPPTDAYYKLRHIVDEVNGLLSTY-STDESLIVSPLLGNVCFASSQYCICFTLGS 323

  Fly   326 FAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGD 390
            |||:|:|||..::|::||||||||:|||.|||||:||.|::::|||||||:|||:||:::|||||
Zfish   324 FAKIYSDTYGDISYMEFAKRLWGDIYFNPKTRKFTKKAPNSNSQRSFVEFVLEPLYKILSQVVGD 388

  Fly   391 VDTTLSDTLAELNVRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHI 455
            |||:|...|.||.:.::|||:|.||:||||||||||.|:.:|.|||||:||.||...|:.|::|.
Zfish   389 VDTSLPRVLDELGIHLTKEELKLNIKPLLRLVCNRFFGEFTGLVDMCVQHIPSPQGGARAKIEHT 453

  Fly   456 YTGPKEGDIYRDMISCNQYGTLMVHSSKMYPNDDCTFFQVLARIVSGTLHAGQEVRVLGENYTLQ 520
            |||..:.|:...|..|:..|.||.|::|||..||...|....|::||||.|||.|:||||||:|:
Zfish   454 YTGGLDSDLGETMSECDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTLQAGQPVKVLGENYSLE 518

  Fly   521 DEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKF 585
            |||||:|..|||||:..:||::|:|||||||||||||.||.||||:||.:....|:..|||||||
Zfish   519 DEEDSQICTVGRLWISVARYQIEVNRVPAGNWVLIEGCDQPIVKTATITEPRGNEEAQIFRPLKF 583

  Fly   586 NTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEHVILGTGELYLDCVMHDLRKM 650
            ||.|:||||||||||||||||||||||||||||.|:|:|||||||||||.|||||||||||||||
Zfish   584 NTASVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGIGELYLDCVMHDLRKM 648

  Fly   651 YSEIDIKVADPVVAFCETVVETSSLKCFAETPNKKNKITMISEPLEKGLAEDIENGTVCINWNKK 715
            |||||||||||||.|||||||||||||||||||||||||||:|||||||||||||..|.|.||:|
Zfish   649 YSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRK 713

  Fly   716 RIGEFFQVNYDWDLLAARSIWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREG 780
            ::|||||..|||||||||||||||||:|||||||||||||||||.||.:||||||||||||||||
Zfish   714 KLGEFFQTKYDWDLLAARSIWAFGPDTTGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREG 778

  Fly   781 PLCEEPIRNVKFKILDGVIANEALHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADC 845
            |||:||||||||||||.|||.|.|||||||:|||||||.|||||||||||||||.||||||||||
Zfish   779 PLCDEPIRNVKFKILDAVIAQEPLHRGGGQVIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADC 843

  Fly   846 VSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIV 910
            ||||||||||||||||||||:.|||:||||||||||||||||||||||||||||.||||||||||
Zfish   844 VSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFALSVFHHWQIV 908

  Fly   911 PGDPLDKSIIIRPLEPQQASHLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELARQDVLINYPL 975
            |||||||||:|||||||.|.||||||||||||||||||||||:||||||||||||:|||::|||:
Zfish   909 PGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVMLNYPM 973

  Fly   976  975
            Zfish   974  973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:464968	60/106 (57%)
		PRK13351	115..957	CDD:481252	648/841 (77%)
eftud2	NP_956802.2	EFTUD2	4..111	CDD:464968	60/107 (56%)
		PRK13351	123..955	CDD:481252	641/832 (77%)