Protein Alignment CG4849 and Efl1

DIOPT Version :10

• Sequence 1: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001101004.1
• Gene: Efl1 / 308789
• RGDID: 1306521
• Length: 1127
• Species: Rattus norvegicus
• Alignment Length: 1116
• Identity: 274/1116 - (24%)
• Similarity: 458/1116 - (41%)
• Gaps: 301/1116 - (26%)

  Fly   118 MEFMADLMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCS 182
            ::.|..|......|||:.::.|:.|||||..|||| .::....:....:|||.|:...||.||.:
  Rat     6 LDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLI-SSNGIISSRLAGKLRYMDSREDEQVRGIT 69

  Fly   183 IKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKH 247
            :|::.::|...:..:: ||:|:.|:||||:||.|.:.|:|:.||.::.:||.|||...|:.:|:.
  Rat    70 MKSSAISLHYAEGSEE-YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQ 133

  Fly   248 AVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTY------------------ 294
            |..|.....:.||||||||:|||..||:||..||:|:.::|.|..|.
  Rat   134 AWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILGQINALTGTLFTSKVLEERAERETESQA 198

  Fly   295 ------------------GAPDDNLLVSPILGNVCFASSLYGFCFTLKSFAKLYADTYEGVAYLD 341
                              ...|..|..||..|||.|.|::.|:.|.::.||::|:... |:....
  Rat   199 KSHSEQGDQVYDWSTGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKI-GIKKEV 262

  Fly   342 FAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLAELNVRV 406
            ..|.||||.|.|.|.:|..|.......:..||:.|||.::.|...|:......:...:..|.:::
  Rat   263 LLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILENIWSLYDAVLKKDKEKVDKIVTSLGLKI 327

  Fly   407 -SKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIY-TG-------PKEG 462
             ::|...|:.:..:..:|::::......:.|..:.:.|||:....:|:.:. ||       |.|.
  Rat   328 GAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDMTSERVEKLMCTGSQTFESLPLET 392

  Fly   463 DIYR-DMISCNQYGT--LMVHSSKMYPND------------------------------------ 488
            ...: ..:.|....|  :::..|||:..|
  Rat   393 QALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHAEKLAAAQ 457

  Fly   489 ----------------------------DCT---------------FFQVLARIVSGTLHAGQEV 510
                                        |.|               .|...||:.||....|:::
  Rat   458 GQAPQGPTQDGGALETSPQEDEPRGEEPDMTSVSRQPAPQEESSQEAFIAFARVFSGVARRGKKI 522

  Fly   511 RVLGENYTLQDEEDSRILQ-----------------------VGRLWVFESRYKVELNRVPAGNW 552
            .|||..|:..|     .||                       :..|::...|...:|..||.||.
  Rat   523 FVLGPKYSPVD-----FLQRVPQGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNV 582

  Fly   553 VLIEGIDQCIVKTSTIVDI-NVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKS 616
            :.|.|:...::|::|:..: :.|.    |.||.|....|:::||||.:|||:|:::.|::.:|::
  Rat   583 LGIGGLQDSVLKSATLCSLPSCPP----FIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQA 643

  Fly   617 YPLLSTRVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFAET 681
            .|.:...::|:||||::..||::|...:.|||:.:::|.|.|::|::.|.||:.:...:....|.
  Rat   644 DPCVQILIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEE 708

  Fly   682 PNKKNKITMISEPLE------KGLAEDIENGTVCINWNKK-------------RIGEFFQVNYD- 726
            ..::.|:.:|.:..|      :|:..| .:|.:.|....|             .:....:.|.|
  Rat   709 IGRQQKVAVIHQTKEEQSKIPEGILVD-SDGLITIPTPNKLATLSVRAIPLPEEVTRILEENSDL 772

  Fly   727 ----------------------------WDL-------LAAR-------SIWAFGPDSTGPNILV 749
                                        |:.       |..|       .||:|||...||||||
  Rat   773 IRSMELLTSSLNEGRNTQAIHQKTQEKIWEFKGKLEKHLTGRKWRNTVDQIWSFGPRKCGPNILV 837

  Fly   750 DDTL---------PSEVDKNLLTAVKD---SIVQGFQWGTREGPLCEEPIRNVKFKILDGVIANE 802
            ..:.         |:..:....:..:|   |||.|||..|..||:||||:..|.| :|:....|:
  Rat   838 SRSEDFQSSVWSGPAGRESKEASRFRDFGNSIVSGFQLATLSGPMCEEPLMGVCF-VLEKWELNK 901

  Fly   803 ALHRG----------------------------------------------------------GG 809
            ....|                                                          .|
  Rat   902 CAEPGASDKQSQGQCDLTGEGQEKSKTCPVGDENQEQQDGYSEPFEETSQKGDSPVIDCYGPFSG 966

  Fly   810 QIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPVSGSPIYTI 874
            |:|.|.:.....|..:...|||......::.|.:|.:..||.||::|.|.|.|:....|:.::.|
  Rat   967 QLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFII 1031

  Fly   875 KAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPL----DKSIIIRPLEPQQASHLARE 935
            ||.:|..:||||..::|..|.|.|....||.||:::|.||.    .:...:...|...:.:.||:
  Rat  1032 KAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARK 1096

  Fly   936 FMIKTRRRKGL 946
            :|...|:||||
  Rat  1097 YMNAVRKRKGL 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:464968
		PRK13351	115..957	CDD:481252	274/1116 (25%)
Efl1	NP_001101004.1	PRK13351	1..1110	CDD:481252	274/1116 (25%)