Protein Alignment CG4849 and Gfm1

DIOPT Version :10

• Sequence 1: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_613057.2
• Gene: Gfm1 / 28030
• MGIID: 107339
• Length: 751
• Species: Mus musculus
• Alignment Length: 877
• Identity: 190/877 - (21%)
• Similarity: 320/877 - (36%)
• Gaps: 230/877 - (26%)

  Fly   131 IRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLR-----YTDTLFTEQERGCSIKATPVTL 190
            |||:.:..|:..||||..:.::..| .:..||.|.:.:     ..|::..|::||.:|::.....
Mouse    47 IRNIGISAHIDSGKTTLTERVLYYT-GRIATMHEVKGKDGVGAVMDSMELERQRGITIQSAATYT 110

  Fly   191 VLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAI 255
            :.:|:.     :||.||||||:|:.|...|:|:.||.||.:.|..||...|..:.:...:.....
Mouse   111 MWKDIN-----INIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVSRQMKRYNVPF 170

  Fly   256 TVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFC 320
            ...|||:||:........|....||.|                          |..|.....|
Mouse   171 LTFINKLDRMGSNPSRALQQMRSKLNH--------------------------NAAFVQIPIG-- 207

  Fly   321 FTLKSFAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIA 385
                    |..| ::|:..|...:.::.|..|....|.........:|.....:.::|
Mouse   208 --------LEGD-FKGIIDLIEERAIYFDGDFGQIVRYDEIPAGLRAAAADHRQELIE------- 256

  Fly   386 QVVGDVDTTLSDTLAELNVRVSKEEMKSNIR--PLLRLVCNRFMGDC------SGFVDMCVEHIK 442
             .|.:.|..|.:...|..: .|..::|..||  .|.|.....|:|..      ...:|..:|::.
Mouse   257 -CVANSDEQLGELFLEEKI-PSVSDLKRAIRRATLSRSFTPVFLGSALKNKGVQPLLDAVLEYLP 319

  Fly   443 SPLE---------NAKRKVDHIYTGPKEGDIYRDM-----ISCNQYGTLMVHSSKMYPNDDCTFF 493
            :|.|         |..::...|...|:..|.:..:     :...::|.|
Mouse   320 NPSEVQNYAILNQNDSKEKTKILMNPQRDDSHPFVGLAFKLEAGRFGQL---------------- 368

  Fly   494 QVLARIVSGTLHAGQEVRVLGENYTLQDEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGI 558
             ...|...|.|..|.         |:.:....:.::|.||....:....::..|.||:...:.||
Mouse   369 -TYVRNYQGELKKGS---------TIYNTRTGKKVRVQRLVRMHADMMEDVEEVYAGDICALFGI 423

  Fly   559 DQCIVKTSTIVD--------INVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNK 615
            |.....|.|..|        |:|||             .:|.||:.|.|.::|.|...|:.:..:
Mouse   424 DCASGDTFTNKDNSDLSMESIHVPE-------------PVISIAMRPSNKNDLEKFSKGIGRFTR 475

  Fly   616 SYPLLSTRVE-ESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFA 679
            ..|......: ||.|.::.|.|||:|:.....:.:.|. .......|.|||.||:|        |
Mouse   476 EDPTFKVHFDPESKETIVSGMGELHLEIYAQRMEREYG-CPCITGKPKVAFRETIV--------A 531

  Fly   680 ETP----NKK--------NKITMISEPLEKGLAEDIENGTVCINWNKKRIGEFFQVNYDWDLLAA 732
            ..|    :||        .|:..:.|||.   .||                 :.::.:.
Mouse   532 PVPFDFTHKKQSGGAGQFGKVIGVLEPLP---PED-----------------YTKLEFS------ 570

  Fly   733 RSIWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDG 797
                             |:|..|.|.|..:.||:    :||.....:|||....:..::|.:.||
Mouse   571 -----------------DETFGSNVPKQFVPAVE----KGFLDACEKGPLSGHKLSGLRFVLQDG 614

  Fly   798 ----VIANEA--LHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARR 856
                |.:||.  :..|.|.:        ..|....|..::||.:.|||.||.:....|:..:.||
Mouse   615 AHHMVDSNEISFIRAGEGAL--------KQALANGTLCIIEPIMSVEVIAPNEFQGTVFAGINRR 671

  Fly   857 RGHVT-QDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSII 920
            .|.:| ||..   ...:|:.|.:|..:.||:.|:||:.|:|:......:..:|
Mouse   672 HGVITGQDGI---EDYFTLYADVPLNNMFGYSTELRSCTEGKGEYTMEYCRYQ------------ 721

  Fly   921 IRPLEPQQASHLAREFMIKTRR---RKGLSED 949
              |..|.....|..:::..|.:   :||.:::
Mouse   722 --PCSPSTQEELINKYLEATGQLPVKKGKAKN 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:464968
		PRK13351	115..957	CDD:481252	190/877 (22%)
Gfm1	NP_613057.2	FusA	45..735	CDD:440248	187/859 (22%)