Protein Alignment CG4849 and mEFG1

DIOPT Version :10

• Sequence 1: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_318822.5
• Gene: mEFG1 / 1279146
• VectorBaseID: AGAMI1_000113
• Length: 744
• Species: Anopheles gambiae
• Alignment Length: 848
• Identity: 179/848 - (21%)
• Similarity: 323/848 - (38%)
• Gaps: 211/848 - (24%)

  Fly   131 IRNVALVGHLHHGKTTFVDCL------IRQTHPQFETMEERQLRYT-DTLFTEQERGCSIKATPV 188
            |||:.:..|:..||||..:.:      |::.|   |...:..:..| |::..|::||.:|::...
Mosquito    41 IRNIGISAHIDSGKTTLTERILFYTGRIKEMH---EVKGKDNVGATMDSMELERQRGITIQSAAT 102

  Fly   189 TLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQ 253
            ..:.:|     :.:||.||||||:|:.|...|:|:.||.||.:.:..||...|..:.:...:...
Mosquito   103 YTIWKD-----HNINIIDTPGHVDFTVEVERALRVLDGAVLVLCSVGGVQSQTLTVNRQMKRYNV 162

  Fly   254 AITVCINKIDRL---------ILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGN 309
            .....|||:||.         .:..||....|:.:|...||
Mosquito   163 PCLAFINKLDRSGANPYRVLGQMRSKLNHNAAFVQLPIGVE------------------------ 203

  Fly   310 VCFASSLYGFCFTLKSFAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVE 374
                |:..|....:|..|..:.:.| |:...:  ..:..||...|..|:....:..::......|
Mosquito   204 ----SNCKGVIDLVKQRALYFEEPY-GLKIRE--DEIPADMRTESAERRQELIEHLSNVDEKIGE 261

  Fly   375 FILEPMYKLIAQVVGDV-DTTLSDTLAELNVRVSKEEMKSNIRPLLRLVCNRF--MGDCSGFVDM 436
            ..||.....:..::|.: .:||......  |.|........::|||..|.:..  .|:
Mosquito   262 LFLEEREATVDDIMGAIRRSTLKRAFTP--VLVGTALKNKGVQPLLDAVLDYLPHPGE------- 317

  Fly   437 CVEHI-----------KSPLENAKRKVDHIYTGPKEGDIYRDMISCNQYGTLMVHSSKMYPNDDC 490
             ||::           |.||..|:...|     |..|..::  :...::|.|
Mosquito   318 -VENVALVEKKDEEPQKVPLNPARDGKD-----PFVGLAFK--LEAGRFGQL------------- 361

  Fly   491 TFFQVLARIVSGTLHAGQEVRVLGENYTLQDEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLI 555
            |:.    |...|.|..|..:      :..:..:..|:.::.||   .|....::|.|.||:...:
Mosquito   362 TYL----RCYQGVLRKGDNI------FNTRSGKKIRLARLVRL---HSNQMEDVNEVYAGDIFAL 413

  Fly   556 EGIDQCIVKTSTIVDINVPEDLYIFRP-LKFNTQSI------IKIAVEPVNPSELPKMLDGLRKV 613
            .|:| |           ...|.::..| |:.:.:||      :.:|::|.|..:.......:.:.
Mosquito   414 FGVD-C-----------ASGDTFVTNPKLELSMESIFVPDPVVSMAIKPTNSKDRDNFAKAIARF 466

  Fly   614 NKSYPLLSTRVE-ESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKC 677
            .|..|......: :..|.::.|.|||:|:.....:.:.|: ..:.:..|.|||.||::.    .|
Mosquito   467 TKEDPTFHFEYDADVKETLVSGMGELHLEIYAQRMEREYN-CPVTLGKPKVAFRETLIG----PC 526

  Fly   678 FAETPNKKN--------KITMISEPLEKGLAEDIENGTVCINWNKKRIGEFFQVNYDWDLLAARS 734
            ..:..:||.        :::.|.|||...     :|.|:          ||
Mosquito   527 EFDYLHKKQSGGQGQYARVSGILEPLPPH-----QNTTI----------EF-------------- 562

  Fly   735 IWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDGVI 799
                          ||:|:.:.|.|..:..::    :||:....:|.|....:..:||::.||
Mosquito   563 --------------VDETMGTNVPKQFIPGIE----KGFRQMAEKGLLSGHKLSGIKFRLQDG-- 607

  Fly   800 ANEALHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDA 864
            |:..:.......:..|:....|.|...:.:::||.:.|||.||.:....|...|.:|.|.:|...
Mosquito   608 AHHIVDSSELAFMLAAQGAIKSVFENGSWQILEPIMMVEVTAPEEFQGTVIGQLNKRHGIITGTE 672

  Fly   865 PVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQ----------AFCL-----SVFHHWQIVPGDP 914
            ...|  .:|:.|.:|..|.||:..:||:.|||:          :.|:     .:.|.:|:..|..
Mosquito   673 GAEG--WFTVYAEVPLNDMFGYAGELRSSTQGKGEFSMEYSRYSPCMPEVQEKLCHEYQVSQGLV 735

  Fly   915 LDK 917
            :||
Mosquito   736 VDK 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:464968
		PRK13351	115..957	CDD:481252	179/848 (21%)
mEFG1	XP_318822.5	None