Protein Alignment CG4849 and efl1

DIOPT Version :10

• Sequence 1: NP_651605.1
• Gene: CG4849 / 43358
• FlyBaseID: FBgn0039566
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_002940146.3
• Gene: efl1 / 100492738
• XenbaseID: XB-GENE-5894854
• Length: 1136
• Species: Xenopus tropicalis
• Alignment Length: 1124
• Identity: 278/1124 - (24%)
• Similarity: 462/1124 - (41%)
• Gaps: 308/1124 - (27%)

  Fly   118 MEFMADLMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCS 182
            :|.:..|......|||:.::.|:.|||||..|||| .::.........:|||.|:...||.||.:
 Frog     6 LEKIVTLQKRAANIRNICILAHVDHGKTTLADCLI-SSNGIISNRLAGKLRYLDSREDEQIRGIT 69

  Fly   183 IKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKH 247
            :|::.::|..:| .::.||:|:.|:||||:||.|.:.|:|:.||.::.:|:.|||...|:.:|:.
 Frog    70 MKSSAISLHYKD-DEEEYLINLIDSPGHVDFSSEVSTAVRLCDGCIIVVDSVEGVCPQTQAVLRQ 133

  Fly   248 AVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVN------------------------ 288
            |..|.....:.||||||||.||||...:||..|:.|:|:||
 Frog   134 AWLENIRPVLVINKIDRLITELKLSCLEAYSHLQKILEQVNAVTGSLFTSKVLEERAEKDMASDV 198

  Fly   289 ---------------GLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKSFAKLYADTYEGVA 338
                           ||..|   .|.:|..||..|||.|||::.|:.||:..||:||:... |:.
 Frog   199 PSETVDGDQVYDWSAGLEET---DDSHLYFSPDQGNVVFASAIDGWGFTIDHFAQLYSQKV-GIK 259

  Fly   339 YLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLAELN 403
            .....|.||||.|.|:|.:|..|.......:..||:.||:.::.|...|:......:...:..|.
 Frog   260 AAVLLKTLWGDYYLNTKAKKIMKGAQSKGKKPLFVQLILDNLWSLYDAVIKREKEKIDKIVLSLG 324

  Fly   404 VRVS-KEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIY-TGPKEGD--- 463
            :::| :|...|:.:..:..:|::::......:.|....:.|||:....:|:.:. .|.:..|
 Frog   325 LKISPRESRHSDPKVHVNAICSQWLPISQAVLSMVCRKLPSPLDIPAERVEKLLCVGSRRFDSLP 389

  Fly   464 -----IYRDMISCNQYGTLMV--------------------------------------HSSKMY 485
                 :....:.|....|..|                                      |:.||.
 Frog   390 QETQQLKETFLKCRSDETAPVIIFVSKMFAVDAKALPQNKQRPLTQEEIALRRELARQRHAEKMA 454

  Fly   486 PN------------DDC---------------------------------TFFQVLARIVSGTLH 505
            .|            ::|                                 ::|...||:.||.:.
 Frog   455 INQEQLPAEQVPSSNECEMPANKENTKGDKQTSHRDPEVVKPEKQEAENKSYFIAFARVFSGIVR 519

  Fly   506 AGQEVRVLGENYTLQDEEDSRI--------------------LQVGRLWVFESRYKVELNRVPAG 550
            .||::.|||..|   |..::.:                    ..:..|::...|....|..||.|
 Frog   520 RGQKIFVLGPKY---DPAETLLKLPLNCTPACDLPGIPHMACCSLDNLYLLMGRELENLEEVPVG 581

  Fly   551 NWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNK 615
            |.:.|.|:::.::|::|   ::.......|.||.|....|:::||||.:|||:|:::.|::.:|:
 Frog   582 NVLGIGGLEEFVLKSAT---LSTSPACPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQ 643

  Fly   616 SYPLLSTRVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETV----------- 669
            :.|.:...::|:||||::..||::|...:.|||:.:::|.:..:.|::.|.||:
 Frog   644 ADPCVEVLIQETGEHVLITAGEVHLQRCLDDLRERFAKIQVSSSAPIIPFRETIIRPPKVDMVNE 708

  Fly   670 -------------VETSSLKC------------FAETPNKKNKITMISEPLEKGLAEDIE----- 704
                         |:....||            ...||||...:::.:.||.:.:.:.:|
 Frog   709 EIGKQQKIAVIHQVKEEQSKCPEGVQVDPDGLVTLTTPNKLATLSVRAMPLPEEVTQLLEKNSDL 773

  Fly   705 ------------NGTVCINWNKKRIGEF--FQVNYDWDLLAAR-------SIWAFGPDSTGPNIL 748
                        .|:..|::|:..|...  |:.|.. .||..|       .||:|||...|||||
 Frog   774 IRTMEQINMALNEGSYTIHFNESAIERITAFKSNLQ-QLLQGRRWRNAVDQIWSFGPRRYGPNIL 837

  Fly   749 VD-----------DTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKI--LD---- 796
            ::           ..|...:.:.......:|||.|||..|..||:||||:..|.|.:  ||
 Frog   838 LNRIEGYDRPSVWQCLEKSIREGKYRNFDNSIVSGFQLATLAGPMCEEPLMGVCFIVEKLDLSRP 902

  Fly   797 ------------------------------GVIAN----------EALHRGG------------- 808
                                          |.:.|          |.:...|
 Frog   903 LLAKDSASQDSEVDTRTEPEHSETGTTGTTGALINNISTSATEETELIPENGARPFSKRKGDLLT 967

  Fly   809 -------GQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPV 866
                   ||:|.|.:.....||.:...|||......|:.|.|:.:..||.||::|.|.|..:...
 Frog   968 DCYGPFSGQLIATMKEACRYAFQVKPQRLMAAMYTCEIMATAEVLGRVYGVLSKREGRVLLEEMK 1032

  Fly   867 SGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPL----DKSIIIRPLEPQ 927
            .|:.::.|||.:|..:||||..::|..|.|.|....||.||:::..||.    .:...:...|..
 Frog  1033 EGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVISSDPFWVPTTEEEYLHFGEKA 1097

  Fly   928 QASHLAREFMIKTRRRKGL 946
            .:.:.||::|...|:||||
 Frog  1098 DSENQARKYMNSVRKRKGL 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4849	NP_651605.1	EFTUD2	4..111	CDD:464968
		PRK13351	115..957	CDD:481252	278/1124 (25%)
efl1	XP_002940146.3	PRK13351	5..1119	CDD:481252	278/1124 (25%)