Protein Alignment Nep7 and Ece1

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_006239337.1
• Gene: Ece1 / 94204
• RGDID: 620293
• Length: 769
• Species: Rattus norvegicus
• Alignment Length: 792
• Identity: 210/792 - (26%)
• Similarity: 341/792 - (43%)
• Gaps: 179/792 - (22%)

  Fly    12 LYTRLAVCILICVILNDCEARSIGDESHENAITDE----TADYLRSHGAMMKSYMNFSVDPCDDF 72
            |.|.||..::.|:.....:.|:   .:....:|:.    |:..|.|        |:.:||||.||
  Rat    71 LVTLLAAGLVACLAALGIQYRT---RTPPVCLTEACVSVTSSILNS--------MDPTVDPCQDF 124

  Fly    73 YEFACGNWKNVK-TPRQSPHRR----SNILDISYTLMDVTEQLLTRTKLAEALNVSAELLVAQRF 132
            :.:|||.|  :| .|....|.|    ||:.:.:..::    :.|.....|.|.....:   ||.:
  Rat   125 FSYACGGW--IKANPVPDGHSRWGTFSNLWEHNQAII----KHLLENSTASASEAEKK---AQVY 180

  Fly   133 YNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWF--NMSAHLSNYGVRSLIHEE 195
            |.:|:.........|.| .:.:|..|||        ||.:. .|.  |....|          :.
  Rat   181 YRACMNETRIEELRAKP-LMELIEKLGG--------WNITG-PWAKDNFQDTL----------QV 225

  Fly   196 ILPQHPFNPYFKLPELGFDHVVHTAHVANTSSRAYQLNEHRMRGYLKEYNLTKDEISAVIEGVFA 260
            :...:..:|:|.        |..:|...|::|...|:::..:....::|.|.|.|...|:.|...
  Rat   226 VTAHYRTSPFFS--------VYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLN 282

  Fly   261 FW---------SEALSIEDKFESDRDKCDLLSEIEEVP---RFGQWRSYYEI----------AWN 303
            :.         .:..||..:.:...|....|:.| .:|   |..:...|:::          |.|
  Rat   283 YMVQLGKLLGGGDEDSIRPQMQQILDFETALANI-TIPQEKRRDEELIYHKVTAAELQTLAPAIN 346

  Fly   304 GIDFYNGSSGGEFCDFYYVEL---------DKVCAKHTEAVA---------NYLAMRFLYRMDDK 350
            .:.|.|..       ||.||:         ||...:....:.         ||:....:.:....
  Rat   347 WLPFLNAI-------FYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSF 404

  Fly   351 LKEPKQPEDQKV---------NCL----MIVQMTLPNL---FNRLYMAEHFTDEKHSEISDMVTE 399
            |.:..|..|:|.         .||    ..|..|..||   ...:::...|.::..:..|:::.|
  Rat   405 LDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILE 469

  Fly   400 MRKAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKN-----EELSDTLIREINNLTIVEGSY 459
            ::||..:.|.:::|:|.:||..|..|...|..:|| |.|     :||.    :..|:.|.|...|
  Rat   470 IKKAFEESLSTLKWMDEDTRRSAKEKADAIYNMIG-YPNFIMDPKELD----KVFNDYTAVPDLY 529

  Fly   460 AQSLINL-----RVLGTYLHRYAGLHADELPKD--------TKPLTLLVGMQVNAFYYNLDNSVY 511
            .::.:..     ||.           ||:|.|.        |.|:       |||:|....|.:.
  Rat   530 FENAMRFFNFSWRVT-----------ADQLRKAPNRDQWSMTPPM-------VNAYYSPTKNEIV 576

  Fly   512 VMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERA 576
            ..||:|..|.|.||.|::|.||.||.::||||||.||.:|..:|..|.:|.||...|...|:::.
  Rat   577 FPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQT 641

  Fly   577 QCYVDYFNQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNEQ 641
            :|.|..:|.|.:.  .:.:.|..|..|||||.|||:||...|:|.:|   ::||:        :.
  Rat   642 ECMVQQYNNYSVN--GEPVNGRHTLGENIADNGGLKAAYRAYQNWVK---KNGAE--------QI 693

  Fly   642 MPGLDLSPEQLFFVGFAQLWCADYEPEHYWEEL-TGAHTVDKYRVLGAVSNNDDFAEVYKCPLGS 705
            :|.|.|:..||||:||||:||:...||...|.| |..|:..::||:|::||:.:|:|.::|||||
  Rat   694 LPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGS 758

  Fly   706 PMHPKAESCRMW 717
            ||:|: ..|.:|
  Rat   759 PMNPR-HKCEVW 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	197/730 (27%)
Ece1	XP_006239337.1	M13	118..767	CDD:341056	197/730 (27%)