Protein Alignment Nep7 and Nepl21

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 755
• Identity: 203/755 - (26%)
• Similarity: 341/755 - (45%)
• Gaps: 117/755 - (15%)

  Fly    20 ILICV---ILNDCEARSIGDESHENAITDETADYLR-SHGAMMKSYMNFSVDPCDDFYEFACGNW 80
            :.||:   :|:...|.:...|......|....:.|| :..|.::|:|:...|||:|||.|:|||:
  Fly    13 LCICIAGHVLSAMVAAAPTSEEDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAFSCGNY 77

  Fly    81 KNVKTPRQSPHRRSNILDISYTLMDVTEQL---LTRTKLAEALNV------SAELLVAQRFYNSC 136
            |.:          ::.|.:......|.|.|   |.| |:.:.||.      :.|.:..:.||.||
  Fly    78 KRI----------NSALSMQVVTTGVFETLTKGLNR-KILKMLNTPHDSHDTPEDIKVKHFYESC 131

  Fly   137 LA--------AELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWFNMSAHLS-NYGVRSLI 192
            |.        :|...|         :|...|..|.::..:|....|.|.|.:|.:: .||:..:.
  Fly   132 LQIKELNSTYSEKLKR---------LIAEFGTMPLLEGSSWQEDDFDWLNTTARMAYRYGITPIF 187

  Fly   193 HEEI---LPQHPFNPYFKLPELGFDHVVHTAHVANTSSRAYQLNEHRMRGYLKEY-----NLTKD 249
            ..|:   |..:..|..: |.:..|.....:.:|.:.::...|...:.::..|:.|     :|.|.
  Fly   188 GIEVNKDLASNTRNRIY-LGQQDFPLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKK 251

  Fly   250 EISAVIEGVFAFWSE-ALSIEDKFES-DRDKCDLLSEIEEVPRFGQWRSYYEIAWNGIDFYNGSS 312
            ....:|:    |..: |..:.|:.|. |..:...|..::|:.|  ::....:|  :.:.|.  |.
  Fly   252 TAKELID----FEVDLAQGLVDESEGLDVGELTQLLTVDEIQR--RYSPTLDI--DRLLFV--SM 306

  Fly   313 GGEFCDFYY----------VELDKVCAKHTEAVANYLAMRFLYRMDDKLKEPK-QPEDQKVNCLM 366
            |....|..|          ||:.|...|.|  ||||:..|.::..   ::.|. .||.|...|:.
  Fly   307 GERISDQIYEYNNRYQQNLVEVIKRTPKRT--VANYIFFRLIWEF---VETPSDSPEKQMKACVD 366

  Fly   367 IVQ----MTLPNLFNRLYMAEHFTDEKHS-EISDMVTEMRKAQRQILES---VEWLDAETRAEAL 423
            :.:    ..|.|:|.|.|     .:||.| ||.:|..:::....:.|.|   :.|::..||..|:
  Fly   367 LTKKYFAKNLDNMFYRRY-----NNEKSSREIDNMWRQLKSTFNETLRSSPALNWIERPTRNLAM 426

  Fly   424 SKEAGITPVIGSYKNEELSDTLIREINNLTIVEGSYAQSLINLRVLGTYLHRYAGLHADELPKDT 488
            :|...:|..:.:|.:    |....|...|.:....|.:::....:||....|      :.|.|..
  Fly   427 AKLQAMTLEVNNYAD----DNFTEEFAELNLQSDDYVENVRYTSLLGAKQMR------EMLHKPA 481

  Fly   489 KPLTLLVGMQVNAFYYN--LDNSVYVMAGVLHP-PAYHRSWPDSLKFGTIGYLIGHELTHGFDTE 550
            ||..  .|.|::....|  ::|::.|...:|.| ..:...:|:::.|||:..||||||.||||..
  Fly   482 KPFE--AGSQLSYTPANILIENTIKVPVALLQPFYIWSDVYPNAIMFGTLASLIGHELIHGFDDS 544

  Fly   551 GSSFDSAGEVRDWWSRKSEAVFQERAQCYVDYFNQYLIPEINQTIRGNETRDENIADAGGLRAAL 615
            |..||..|..:|||..||.:.|.:|..|:...:.:|:...|.  ::.:..:.|||||.||:|.|.
  Fly   545 GRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQ--LKESTAQSENIADNGGMRLAY 607

  Fly   616 TGYRN-HMKQLQ-RSGADGETLAHKNEQMPGLDLSPEQLFFVGFAQLWCADYEPE-HYWEELTGA 677
            |.||. :..||. .:||...|    .|.:|.|..:.:||||:.|||.||.|..|. ...:..|..
  Fly   608 TAYRKWYENQLTLPNGAQDMT----KETLPNLRYTAKQLFFISFAQSWCNDAHPSVKALQVSTDQ 668

  Fly   678 HTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPKAESCRMW 717
            |...::||:|::||.::|::.:.||.||.|:| :|.|.::
  Fly   669 HMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNP-SEKCILY 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	191/701 (27%)
Nepl21	NP_651646.2	M13	63..704	CDD:341056	191/700 (27%)