Protein Alignment Nep7 and Nepl12

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 721
• Identity: 370/721 - (51%)
• Similarity: 499/721 - (69%)
• Gaps: 37/721 - (5%)

  Fly    10 LPLYTRLAVCILICVILNDCEARSIGDESHENAITD------ETADY-LRSHGAMMKSYMNFSVD 67
            |.|.:.:.:.:::..:|.||||||:.|.| ||:.::      ..|:| |:.:...||||||.||:
  Fly     6 LKLISLMLLWVIVAAVLTDCEARSLVDRS-ENSDSNGSSTNRSAAEYQLQEYAEFMKSYMNQSVE 69

  Fly    68 PCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVTEQLLTRTKLAEALNVSAELLVAQRF 132
            ||::|||:||||::|||..|.||..|||:.|::|||:|:|||||.|..||||||||:||.|||||
  Fly    70 PCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNVSSELAVAQRF 134

  Fly   133 YNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWFNMSAHLSNYGVRSLIHEEIL 197
            ||:||.|.|.|..||||||||:|||:|||||||.|||.||:|:|.||||||:|||...||.|.:.
  Fly   135 YNACLGANLHPFNAADPAYLSLIRSIGGFPAVDGDAWKASNFNWINMSAHLANYGANGLIRETLQ 199

  Fly   198 PQHPFNPYFKLPELGFDH-VVHTAHVANTSSRAYQLNEHRMRGYLKEYNLTKDEISAVIEGVFAF 261
            .::||.||.||||||||| :||..:::..::||::|||.||.|||:.:.|.:|.|...|.|||||
  Fly   200 LRYPFEPYTKLPELGFDHIIVHEENISRNTTRAFRLNEERMHGYLRAFGLPEDRIREAIAGVFAF 264

  Fly   262 WSEALSIEDKFESDRDKCDLLSEIEEVPRFGQWRSYYEIAWNGIDFYNGSSGGEFCDFYYVELDK 326
            |.:||.|.       .:|::.........|.|...||.|:|:|:.    |:...|||||||||||
  Fly   265 WRDALEIP-------PQCEVFDPYRIKRVFPQSEYYYNISWSGLH----STNKLFCDFYYVELDK 318

  Fly   327 VCAKHTEAVANYLAMRFLYRMDDKLKEPKQPEDQKVNCLMIVQMTLPNLFNRLYMAEHFTDEKHS 391
            |||:|.:||||||||:.|||.|.|||.|:.   |:..|.:.:..::..|||:||||.:|::.|..
  Fly   319 VCARHRKAVANYLAMKLLYRFDPKLKAPRY---QRNYCSVTLYQSMRFLFNKLYMANNFSEAKRL 380

  Fly   392 EISDMVTEMRKAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKNEELSDTLIREINNLTIVE 456
            |:|:||.|:||:.|:.||..:|||||:||.||.||:.|.|.|||::::.|||.:|||||:|.::|
  Fly   381 EMSEMVRELRKSLRKALEDADWLDAESRARALLKESRIQPRIGSFQDDALSDRIIREINSLKVIE 445

  Fly   457 GSYAQSLINLRVLGTYLHRYAGLHADELPKDTKPLTLLVGMQVNAFYYNLDNSVYVMAGVLHPPA 521
            ..||::.|||:.|...::|::..|..||..||||..:|.|:||.|.||..|||:.|||||:.||.
  Fly   446 DRYAETNINLQHLVVQINRFSSRHFQELTNDTKPQKILTGLQVGAGYYTPDNSINVMAGVVEPPI 510

  Fly   522 YHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCYVDYFNQY 586
            |.|..|.||||||:|:::||||.|||||..|.||..|.:....|..|:...::||:||:||:.:|
  Fly   511 YQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALEDRAECYMDYYGKY 575

  Fly   587 LIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNEQ-----MPGLD 646
            .:|||::.:.|..|.||||||..|||.|||.||:|.:||         |.|..::     |||||
  Fly   576 QVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQL---------LEHPGQERISDAMPGLD 631

  Fly   647 LSPEQLFFVGFAQLWCADYEPEHYWEELTGAHTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPKA 711
            |:||||||:|||||:|:.||.||||:.|:..||.|::||||.:||::||...|.|.:||.|.|.|
  Fly   632 LTPEQLFFLGFAQLFCSHYEEEHYWKGLSDVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGA 696

  Fly   712 ESCRMW 717
            ::||:|
  Fly   697 KTCRLW 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	344/654 (53%)
Nepl12	NP_649924.1	M13	68..700	CDD:341056	344/654 (53%)