Protein Alignment Nep7 and phex

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001307259.2
• Gene: phex / 386969
• ZFINID: ZDB-GENE-030103-2
• Length: 745
• Species: Danio rerio
• Alignment Length: 765
• Identity: 225/765 - (29%)
• Similarity: 353/765 - (46%)
• Gaps: 99/765 - (12%)

  Fly    12 LYTRLAVCILICVILNDCEARSIGDESHENAITDETADYLRSHGAMMKSYMNFSVDPCDDFYEFA 76
            |...||||:.:|:.|...........|:|:.......  :.:.|::: |.|:.|||||||||::|
Zfish    21 LKAALAVCVCVCIALLIAVITVSQKASNEDLCLGPHC--VEAAGSIL-SKMDQSVDPCDDFYQYA 82

  Fly    77 CGNW-KNVKTPRQS------PHRRSNILDISYTLMDVTEQLLTRTKLAEALNVSAELLVAQRFYN 134
            ||.| :....|..|      |..|.|: |:.  |.::.||.: |:...||:. .|::|     |.
Zfish    83 CGGWLRENPIPEDSSSYGIYPWLRQNV-DLK--LKELLEQPV-RSGDIEAVK-KAKVL-----YA 137

  Fly   135 SCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSW----FNMSAHLSNYGVRS----- 190
            ||:.........|:|...::.:....:|.:. ||..:|| .|    ||:...|:.  :||
Zfish   138 SCMNESALEIEDANPLLKNLKQKEFRWPVLG-DALGSSS-RWVESQFNLLETLAQ--IRSQHSKS 198

  Fly   191 -LIHEEILPQHP-FNPY-FKLPELGFDHVVHTAHVANTSSRAYQLNEHRMRGYLKEYNL----TK 248
             ||...:.|... .|.| .||.:..........::.||:..  |:....:...:.:.::    ::
Zfish   199 VLIRLFVAPDDKNSNQYIIKLDQASLSLSSREDYITNTTEA--QMYREALLRLMVDVSVMLGASE 261

  Fly   249 DEISAVIEGVFAFWSEALSIEDKFESDR-----DKCDLLSEIEEVPRFGQWRSYYEIAWNGIDFY 308
            ....|.::.|..|..:...|...:|:..     :|..|......||.| .|..:.. |....:.|
Zfish   262 QAAEAQMKSVLDFEMKLAQIVIPYENRTSENMYNKYSLSKLQRTVPDF-NWLGFVR-AVIDTELY 324

  Fly   309 NG---SSGGEF---CDFYYVELDK-VCAKHTEAVANY------------LAMRFLYRMDDKLK-- 352
            ..   ||..:.   ...|:.:|.| :.|..|..||||            |:.|||||..|..:
Zfish   325 PDLKISSSEQVIVRAPQYFKDLFKLINATDTRTVANYVIWRSVFSRITTLSRRFLYRYLDFARVT 389

  Fly   353 ---EPKQPEDQKVNCLMIVQMTLPNLFNRLYMAEHFTDEKHSEISDMVTEMRKAQRQILESV-EW 413
               ....|...|  |:..|:.||.....||::.:||.::|...:.:::..:|.|...|||.. ||
Zfish   390 TGTTSLTPRWDK--CVNYVENTLIYAAGRLFVDKHFQEDKKHMMEELINGIRWAFIDILEKENEW 452

  Fly   414 LDAETRAEALSKEAGITPVIGSYKNEELSDTLIRE-INNLTIVEGSYAQSLINLRVLGTYLHRYA 477
            :|.||:.:|:.|...:.|.:| |.:..|:||.|.| |..|......|..::  ::.|........
Zfish   453 MDEETKRKAIDKAHAVLPKVG-YPDFILNDTYINEDIKRLAFTMTDYFGNV--MQTLKFIAQSDI 514

  Fly   478 GLHADELPKD---TKPLTLLVGMQVNAFYYNLDNSVYVMAGVLHPPAY-HRSWPDSLKFGTIGYL 538
            |.....:|:.   |.|.|      |||||.:..|.:...||.|..|.: ..::|.||.:|.||.:
Zfish   515 GWLRKTVPRTEWFTNPTT------VNAFYSSSTNQIRFPAGELQKPFFWGLNYPRSLSYGAIGVI 573

  Fly   539 IGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCYVDYFNQYLIPEINQTIRGNETRDE 603
            :|||||||||..|..:|..|.:..|||..|...|.|:.||.:|.:|.|...|....::|..|..|
Zfish   574 VGHELTHGFDNNGRKYDKDGNLDQWWSNSSINRFTEKTQCMIDQYNSYYWKEAGLNVKGKRTLAE 638

  Fly   604 NIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNEQMPGLDLSPEQLFFVGFAQLWCADYEPE 668
            ||||.||:|.:...||..::: :|.|.: |.|      :||:.|:..||||:.:|.:.|..|.||
Zfish   639 NIADNGGIRESFRAYRRWVEK-ERGGVE-EPL------LPGVGLTHNQLFFLSYAHVRCNAYRPE 695

  Fly   669 HYWEEL-TGAHTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPKAESCRMW 717
            ...::: :|||:..||||:||:||.::|.:.:.||..|.|:...||||:|
Zfish   696 AARDQIQSGAHSPPKYRVIGAMSNFEEFRKAFNCPETSIMNRGTESCRVW 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	209/707 (30%)
phex	NP_001307259.2	None