Protein Alignment Nep7 and Nep3

DIOPT Version :9

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001245775.1
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 755
• Identity: 198/755 - (26%)
• Similarity: 332/755 - (43%)
• Gaps: 177/755 - (23%)

  Fly    57 MMKSYMNFSVDPCDDFYEFACGNW-KNVKTPRQSPHRRSNILDISYTLMDVTEQLLTRT---KLA 117
            ::|| ::.:||||||||.::|..| ||      :|.........::..::...||:.|.   |.|
  Fly   115 ILKS-IDVTVDPCDDFYGYSCNQWIKN------NPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPA 172

  Fly   118 EALNVSAELLVAQRFYNSCLAAE-----LFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWF 177
            ::....|| ..|:.:|.|||.|:     |..:|..|     ::..:||        ||.:. |.:
  Fly   173 KSFKSDAE-RKAKVYYESCLDADEHMEKLGAKPMND-----LLLQIGG--------WNVTK-SGY 222

  Fly   178 NMSAHLSNYGVRSLIHEEILPQHPFNPYFKLPELGFD------HVVH---------TAHVAN--T 225
            |::.....:.:: ::|.    ::.||..|.. .:|.|      ||:.         ||...|  |
  Fly   223 NVANWTMGHTLK-ILHN----KYNFNCLFGW-AIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKT 281

  Fly   226 SSRAYQLNEHRMRGYLKEYNLTK---------DEISAVIEGVFAFWSEALSIEDKFESDRDKCDL 281
            .:....|||     |: || :||         .:..|.:.||..|..:..:|....|..|::..:
  Fly   282 DNHRKVLNE-----YI-EY-MTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAM 339

  Fly   282 -----LSEIEEVPRFGQWRSYYEIAWNGIDFYNGSSGGEFCDFYYVELDKVCAKHTEAVANYLAM 341
                 |.::.::..|..|..:::.|...:       |....|             .|.|..| |.
  Fly   340 YHPMQLRQLSKLAPFLNWTDHFDNAMQMV-------GRRVTD-------------DEVVVVY-AP 383

  Fly   342 RFLYRMDDKLKEPKQPEDQKV--NCLMIVQ--MTLPNLFNR------------------------ 378
            .||..:.|.:.:.:|.|:.|:  |..::.|  .||.:..::
  Fly   384 DFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWR 448

  Fly   379 ----------------LYMAEHFTDEKHSEISDMVTEMRKAQRQILESVEWLDAETRAEALSKEA 427
                            :::.:.|..|.......|:.|:|:|.:..|:::.|:|.:||.:|:.|..
  Fly   449 YCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKAN 513

  Fly   428 GITPVIG--SYKNEELSDTLIREINNLTIVEGSYAQSLINLRV--LGTYLHRYAGLHADELPKDT 488
            .|:.:||  .|..:.:.  |.::...|.|...:|.::.|.:.:  |.:.|.|     .|:....|
  Fly   514 QISDMIGFPDYILDPVE--LDKKYAELNITPNAYFENNIQVAIYNLKSNLKR-----LDQPVNKT 571

  Fly   489 K----PLTLLVGMQVNAFYYNLDNSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDT 549
            .    |.|      |||:|....|.:...||:|..|.:..:.|.||.||.:|.::||||||.||.
  Fly   572 NWGMTPQT------VNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDD 630

  Fly   550 EGSSFDSAGEVRDWWSRKSEAVFQERAQCYVDYFNQYLIPEIN-QTIRGNETRDENIADAGGLRA 613
            :|..:|..|.:..||..||...|.|:::|....::.|   ::| :|:.|.:|..|||||.|||:|
  Fly   631 QGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGY---KMNGRTLNGKQTLGENIADNGGLKA 692

  Fly   614 ALTGYRNHMKQLQRSGADGETLAHKNEQMPGLDLSPEQLFFVGFAQLWCADYEPE-HYWEELTGA 677
            |.     |..|..:|..|.:.|     ::|||:|:..|||||.|||:||:....| :..:.....
  Fly   693 AY-----HAYQRTKSDRDVDIL-----KLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDP 747

  Fly   678 HTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPKAESCRMW 717
            |:..::||:|.:||..:||||::|..|..|:| .|.|.:|
  Fly   748 HSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNP-TEKCEVW 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	PepO	60..717	CDD:226118	196/750 (26%)
		M13	66..715	CDD:189000	194/742 (26%)
Nep3	NP_001245775.1	M13	123..784	CDD:189000	194/742 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850