Protein Alignment Nep7 and Nepl3

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 793
• Identity: 149/793 - (18%)
• Similarity: 252/793 - (31%)
• Gaps: 270/793 - (34%)

  Fly     1 MLSISSYFRLPLYTRLAVCILICVILNDCE--ARSIGDESHENAITDETADYLRSHGAMMKSYMN 63
            |:...||..|. :..|.:|..:|....:.|  .|.:.|                         |:
  Fly     1 MMESRSYLSLS-WLLLLLCSTVCSANPNLEIMKRMLDD-------------------------MD 39

  Fly    64 FSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMD-VTEQLLTRTKLAEALNVSAELL 127
            ..|:||.:||.   .:.||:|.     |..:.:.|....|.| :..::..:....|.|
  Fly    40 EKVEPCHNFYN---SSQKNLKW-----HAFATVSDQFQLLFDGIENEVFEKHSFEEKL------- 89

  Fly   128 VAQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRD---------AWNASSFSWFNMSAHL 183
              ||.|..|...|   ||:. ..|..:::     |..|.:         .|....|.|....|.|
  Fly    90 --QRLYKICSTME---RPSL-LRYFELVK-----PGEDLNWPFLTPRGGKWPKEKFQWMEALARL 143

  Fly   184 SNYGVRSLIHEEILPQHPFNPYFKLPELGFDHVVHTAHVANTSSRAYQLNEHRMRGYLKEYNLTK 248
            ..||...::....:.|.| |.....|.:.|:                           |:|
  Fly   144 RRYGFNDIMFGMSIRQDP-NSDSGQPIVVFE---------------------------KKY---- 176

  Fly   249 DEISAVIEGVFAFWSEAL------------------SIEDKFESD-------RDKCDL----LSE 284
                   :.:|.| .|:|                  :|::.::||       ||...:    |.:
  Fly   177 -------DSLFRF-IESLQNIGLPPKLAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKRISLGQ 233

  Fly   285 IEEVPRFG-QWRSYYEIAWNGIDFYNGSSGGEFC-DF-------YYVE--LDKVCAKHTEAVANY 338
            :|   .:| ....|.||.:          |..|. ||       ||:.  .:.:.|..::.||||
  Fly   234 LE---IYGVSLTKYLEIVF----------GRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANY 285

  Fly   339 LAMRF-LYRMDDKLKEPKQPEDQKVNCLMIVQMTLPNLFNRLYMAEHFTDEKH--------SEIS 394
            |..|| .|.|...:|...       :|:..::.::....|.|: .|.....|.        .:|.
  Fly   286 LTARFSFYIMFTFMKHGD-------SCVTTMRQSMEFASNLLF-EERILGRKKLRSYQNQAGKIF 342

  Fly   395 DMVTEMR--KAQRQILE--SVEWLDAETRAEALSKEAGITP--------VIGSYK------NEEL 441
            |.:.:..  :.:|.:|:  ..|....:.:...||...|..|        |...||      :|||
  Fly   343 DAIRQQLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDEEL 407

  Fly   442 SDTLIREINNLTIVEGSYAQSLI---NLRVLGTYLHRYAGLHADELPKDTKPLTLLVGMQVNAF- 502
            :...::.:.:.|..|    .||:   |.:.....||.|             |::       |.|
  Fly   408 ATAHLKVLEHRTRAE----LSLLDQPNFKDRRYMLHSY-------------PIS-------NFFF 448

  Fly   503 ---YYNLDNSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWW 564
               |....|::||....|...::.....|..|...:|...|.|:...||
  Fly   449 ETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTPLGIRFGLEMLKSFD---------------- 497

  Fly   565 SRKSEAVFQERAQCYVDYFNQYLIPEINQ-TIRGNE-----TRDENIADAGGLRAALTGYRNHMK 623
                  :|    .|.....|...:.:.|| |..|:|     |:|..::........|     |:.
  Fly   498 ------LF----NCKHHKVNMLQLFDDNQITTAGDECVSAWTQDNLLSQRDQYLVVL-----HLV 547

  Fly   624 QLQRSGADGETLAHKNEQMPGLDLSPEQLFFVGFAQLWCADYEPEHYWEELTGAHTVDKYRVLGA 688
            . :...|:|...:.:......:.|  .:|||..|.|   :.:....|:    |:..|:....:.:
  Fly   548 H-EAYFAEGSKFSQRQPNFTTMSL--RELFFFRFGQ---SSFGQTLYF----GSDFVEGGSPINS 602

  Fly   689 VSNNDDFAEVYKC 701
            ::....|...:.|
  Fly   603 LTRLPVFVRTFNC 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	138/726 (19%)
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	95/482 (20%)