DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nep7 and Nep6

DIOPT Version :9

Sequence 1:NP_651603.1 Gene:Nep7 / 43356 FlyBaseID:FBgn0039564 Length:717 Species:Drosophila melanogaster
Sequence 2:NP_001245645.1 Gene:Nep6 / 32234 FlyBaseID:FBgn0030425 Length:655 Species:Drosophila melanogaster


Alignment Length:778 Identity:185/778 - (23%)
Similarity:297/778 - (38%) Gaps:191/778 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 ISSYFRLPLYTRLAVCILICVILNDCEARSIGDESHENAITDETADYLRSHGAMMKSYMNFSVDP 68
            :||..||.:.  |.|.:|......||:.:...|...|                         |.|
  Fly     5 LSSITRLVVI--LGVMLLKLAAAQDCQQQLDNDTDAE-------------------------VKP 42

  Fly    69 CDDFYEFACGNW-KNVKTPRQSPH--RRSNILDISYTLMDVTEQLLTRTKLAEALNVSAELLVAQ 130
            |::|:::||||| .|........|  |...:.::...|:...|:..:....:...:|:.......
  Fly    43 CENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFSANTSVTTSTAQLG 107

  Fly   131 RFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWFNMSAHLSNYGV----RSL 191
            ..|..||.:....|...|    ::.||...||.:...  ...||.|...:|.|..||.    |.|
  Fly   108 TLYRCCLLSGQSIRTYTD----ALSRSGANFPLLANH--TGGSFDWVLANAALRTYGAQGLWRLL 166

  Fly   192 IHEE----------ILPQHPFNPYFKLPELGFDHVVHTAHVANTSSRAYQLNEHRMRGYLK---- 242
            :.:.          :||     |.|.|  ||.|.               :|||...:.|||    
  Fly   167 VKDNWQSADQRIFYMLP-----PKFDL--LGRDD---------------ELNEFLYQRYLKILLL 209

  Fly   243 EYNLTKDEISAVIEGVFAFWSEALSIEDKFESDRD------KCDLLSEIE-EVPRFGQWRSYYEI 300
            |..|.....:.:.|.:.||   ..|::....:|.:      |...|.::| ::||. :.:.|:|.
  Fly   210 ELGLRVRRAALLAEKLVAF---EKSLQKLLPNDAEQTLVLRKPQSLKDLESQLPRL-ELKRYFET 270

  Fly   301 AWNGIDFYNGSSGGEFCDFYYVE-LDKVCAKHTE---AVANYLAMR----FLYRM--DDKLKEPK 355
            ...||| ::..:.....|..|:: |.::.|:||.   .::.:|.::    |..|:  ||||    
  Fly   271 ILEGID-WDSKTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFELRLHDDDKL---- 330

  Fly   356 QPEDQKVNCLMIVQMTLPNLFNRLYM----AEHFTDEKHSEISDMVTEMRKAQRQ---ILESVEW 413
              .:|:.:||..::..:|....||.|    .|.:.|...:.|..:....|..::|   :|...|.
  Fly   331 --GNQRNHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTAIQQIAVLFRDLKQQFELVLNETEV 393

  Fly   414 L--DAETRAEALSKEAGI--------TPVIGSYKNEELSDTLIREINNLTIVEGSYAQSLINLRV 468
            .  |..||..|..|...:        .|:.|.....:|....     :..:::.|.:|:.:..| 
  Fly   394 FNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTPQLGGNC-----DANLLQLSLSQAKLEYR- 452

  Fly   469 LGTYLHRYAGLHADELPKDTKPLTLLVGMQVNAFYYNLDNSVYVMAGVLHPPAYHRSWPD----- 528
                  :..|.....:|.|  ||:      |||:|....|.:.:..|::..|...:....     
  Fly   453 ------QVFGEPVTSVPAD--PLS------VNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTR 503

  Fly   529 -SLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRD-WWSRKSEAVFQERAQCY--VDYFNQYLIP 589
             .|..| :||::.||:.|.||.:|.::|:.|::.: .||.::...|..||.||  |.|.|..|  
  Fly   504 AKLSAG-LGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGCYLGVRYSNATL-- 565

  Fly   590 EINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNEQMPGLDLSPEQLFF 654
                      |.:|||||..|||.||..||:      ||||                 :..:.||
  Fly   566 ----------TVNENIADTEGLRLALDTYRH------RSGA-----------------TNLRTFF 597

  Fly   655 VGFAQLWCADYEPEHYWEELTGAHTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPKAESCRMW 717
            |.|||.||..........:    |.....||...|.|..:|.:.::|...|.|:| ...|.:|
  Fly   598 VAFAQNWCGTVASTSGLSQ----HAGHAERVNNVVGNMPEFGDTFECKATSQMNP-VNKCHIW 655

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nep7NP_651603.1 PepO 60..717 CDD:226118 173/720 (24%)
M13 66..715 CDD:189000 172/712 (24%)
Nep6NP_001245645.1 PepO 35..655 CDD:226118 175/744 (24%)
M13 40..653 CDD:189000 172/712 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45454933
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3590
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D282463at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR11733
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
54.850

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