Protein Alignment Nep7 and Nep1

DIOPT Version :9

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 724
• Identity: 207/724 - (28%)
• Similarity: 338/724 - (46%)
• Gaps: 102/724 - (14%)

  Fly    47 TADYLRSHGAMMKSYMNFSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVTEQLL 111
            |.:.:|: .|.:.|.|:.:.|||:||:::|||.|..:   ...|..||:|  .::.::...:|::
  Fly   175 TQECVRT-AASLLSAMDLNSDPCEDFFQYACGTWNKM---HPIPEDRSSI--STFEVLSDQQQVI 233

  Fly   112 TRTKLAEALNV--SAELLVAQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSF 174
            .|..|.|.::.  :...:.|:.|:.||:..... |.........|::||||:|.::|: |:..:
  Fly   234 LRAVLEEPIDERDNKATIKAKTFFKSCMDIPQI-RKIGTGRLKQVLQSLGGWPVIERN-WSPPA- 295

  Fly   175 SWFNMSAHLSNYGVRSLIHEEILPQHPFN---PYFKLPELGFDHVVHTAHVANTSSRAYQLNEHR 236
                           .|..|.::.|...|   |......:|.|....:.::.......|.|....
  Fly   296 ---------------DLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRD 345

  Fly   237 MRGYLKE--------YNLTKDEI-----------SAVIEGVFAFWSEALSIEDKFESDRDKCD-- 280
            .  ||||        |:....::           :|.:|.|..|.::.:::... |:||....
  Fly   346 Y--YLKESSANDRRAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLP-EADRHDTSLV 407

  Fly   281 ----LLSEIEEVPRFGQWRSYYEIAWN-GIDFYNGSSGGEFCDFYYVELDKVCAKHTE--AVANY 338
                ||.|::|:....||:.|.:.|.. ||..........:...|..|:.|:.| ||:  .|.||
  Fly   408 YRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILA-HTDRRVVHNY 471

  Fly   339 ----LAMRFLYRMDDKLKEPKQPEDQKV------------NCLMIVQMTLPNLFNRLYMAEHFTD 387
                |.|..:..|.|:.:. ::.|.:|:            .|:......|......|::.::|..
  Fly   472 MLWRLVMSLMSHMIDEYQR-ERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQ 535

  Fly   388 EKHSEISDMVTEMRKAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKNEELSDTLIREINNL 452
            |......:|:..:|.|..::|...:|:|.||||.|..|...:...||..:....:..|.:|..||
  Fly   536 ESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNL 600

  Fly   453 TIVEGSYAQSLINLRVLGTYLHRYAGLHADELPKD---TKPLTLLVGMQVNAFYYNLDNSVYVMA 514
            |||..::..::  |.:|.....:...|....:.|:   |:|..      |||||....|.:...|
  Fly   601 TIVPDNFINNV--LSILQWESEKMLRLLRQPVDKEKWTTEPAV------VNAFYNPNKNDIVFPA 657

  Fly   515 GVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCY 579
            |:|.|..|.:.:|.||.:|.||.:||||:|||||.:|..||..|.:..||:..:...|:||.||.
  Fly   658 GILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCV 722

  Fly   580 VDYFNQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNEQMPG 644
            :|.:::|.|.|::..:.|..|:.|||||.|||:.|...|:.           .|||..:.:|:||
  Fly   723 IDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKK-----------WETLHGREQQLPG 776

  Fly   645 LDLSPEQLFFVGFAQLWCADYEPEHYWEELTGA-HTVDKYRVLGAVSNNDDFAEVYKCPLGSPMH 708
            |:::.:||||:.:||:||....||....::..| |:....||||.:||:.|||..|||||||.|:
  Fly   777 LNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMN 841

  Fly   709 PKAESCRMW 717
            | ||.|.:|
  Fly   842 P-AEKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	PepO	60..717	CDD:226118	203/709 (29%)
		M13	66..715	CDD:189000	200/701 (29%)
Nep1	NP_001284925.1	M13	194..847	CDD:189000	200/700 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454965
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4162
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800