Protein Alignment Nep7 and nep-25

DIOPT Version :9

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 687
• Identity: 124/687 - (18%)
• Similarity: 229/687 - (33%)
• Gaps: 246/687 - (35%)

  Fly    58 MKSYMNFSVDPCDDFYEFACGNWK----------NVKTPRQSPHRRSNILDISYTLMDVTEQLLT 112
            :|.:.:||||||.|||...| .||          .:|....:.:|:.:.....:...|.
 Worm    32 IKKHADFSVDPCVDFYAHVC-PWKVERYFMEDLSKLKAGMVAKYRKKHPKFDKFKGEDA------ 89

  Fly   113 RTKLAEALNVSAELLVAQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWF 177
             ..:||||    :.|..::..:.|..::  ||                             .|.|
 Worm    90 -FAIAEAL----KQLNIEQLKSECKPSK--PR-----------------------------LSSF 118

  Fly   178 NMSAHLSNYGVRSLIHEEILPQHPFNPYFKLPELGFDHVVHTAHVANTSSRAYQLNEH-----RM 237
            .:||. .|..:.: :.|.:.|             ||::              |...|.     :.
 Worm   119 FISAQ-DNRTIEN-VDEVLFP-------------GFEN--------------YPCEEKAAIIIKE 154

  Fly   238 RGYLKEYNLTKDEISAVIEG-VFAFWSEALSIEDKFESDRDKCDLLSEIEEVPRFGQWRSYYEIA 301
            .|.:::|..|:..:.:.:.| :.:...|.|.::.:...::.|..:..||.:.|
 Worm   155 VGEIEDYTTTRSVLVSAVNGFITSKLVEKLDVKARKLFNKFKSVISKEIIKTP------------ 207

  Fly   302 WNGIDFYNGSSGGEFCDFYYVELDKVCAKHTEAVANYLAMRFLYRMDDKLKEPKQPEDQKVNCLM 366
            |                          ||:.:|:..|:.
 Worm   208 W--------------------------AKNYKAIEQYVE-------------------------- 220

  Fly   367 IVQMTLPNLFNRLYMAEHFTDEKHSEISDMVTEMRKAQRQILESVEWLDAETRAEALSKEAGITP 431
                .|.|:..|.:.....|.:|..|:.:      ..::...:.::...::..||.:.|.
 Worm   221 ----ALSNITFRTFADVRITVKKSMELYE------STEKDCRKKLDVAFSQPTAELVCKG----- 270

  Fly   432 VIGSYKNEELSDTLIREINNLTIVEGSYAQSLINLRVLGTYLHRYAGLHADELPKDTKPLTLLVG 496
             :.:.|.|||.|..|.:|                                  .|:|...:...|.
 Worm   271 -VATRKAEELLDEPIEDI----------------------------------FPQDQAGILKDVW 300

  Fly   497 MQVNAFYYNLDNSVYV---MAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAG 558
            ...|:|    |||||:   ...:|:...:      |..:|:||:.:.||:.|....:.:..|.
 Worm   301 QMFNSF----DNSVYIGNEFLLLLNTDYF------SDLYGSIGFSMIHEIMHTLVFDDNDLDK-- 353

  Fly   559 EVRDWWSRKSEAVFQERAQCYVDYF-----NQYLIPEINQTIRGNETRDENIADAGGLRAALTGY 618
            .:...|::.::.| :::|....:.|     ...:.|..|.|:    |.:|:.||....|.|...|
 Worm   354 PLSKLWTKNADCV-KDQALKTCETFPTVTEMHNMKPACNTTV----TFEEDAADLAAYRIAWRIY 413

  Fly   619 RNHMKQLQRSGADGETLAHKNEQMPGLD-LSPEQLFFVGFAQLWC-ADYEPEHYWEELTGAHTVD 681
            .|             :.|.|. .:|..: |..:||||.|.|..:| .|......::.|  ||:.:
 Worm   414 EN-------------SYARKT-VVPNYEALDKKQLFFYGAAVFFCNQDGMSRVPFQNL--AHSNN 462

  Fly   682 KYRVLGAVSNNDDFAEVYKC-PLGSPMHPKAESCRMW 717
            ..||...:|....|::.:|| |....:..:|:.|.::
 Worm   463 YQRVNSLMSQMKQFSDAFKCKPTDKMITNRAKHCELY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	PepO	60..717	CDD:226118	123/683 (18%)
		M13	66..715	CDD:189000	120/675 (18%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	51/216 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910