Protein Alignment Nep7 and nep-24

DIOPT Version :9

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 127/593 - (21%)
• Similarity: 224/593 - (37%)
• Gaps: 143/593 - (24%)

  Fly    57 MMKSYMNFSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNI-LDISYTLMDVTEQLLTRTKLAEAL 120
            |:.:|.:.||||||:|::||||        |:..|...:| ...:.|:.::.::.|.:.:.:.:.
 Worm    49 MLHNYHDPSVDPCDNFHQFACG--------REHEHETEDIYTKKTKTINNIMKRFLKKNETSRSK 105

  Fly   121 NVSAELLVAQRFYNSCLAAELFPRPAADPAYLSV---IRSLGGFPAVDRDAWNASSFSWFNMSAH 182
            :.:|    .:..|.:|...|.....:.:.|...:   |:|:|.:|.|| |.|:.|.|...:...:
 Worm   106 SENA----MRTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVD-DKWDESKFDLNDFLVN 165

  Fly   183 L-----SNYGVRSLIHEEILPQHPFNPYFKL------PELGFDHVVHTAHVAN--TSSRAYQLNE 234
            |     .|:|:..:..           |..:      ||..:.|.|......:  ..:.:.|.|.
 Worm   166 LVRLGRKNFGLFQMAR-----------YVNVRNFAIGPEAAWRHNVDLGKTISEILKANSVQTNN 219

  Fly   235 HRMRGYLKEY-NLTK----DEISAVIEGVFAFWSEALSIEDKFESDR--------DKCDLLSEIE 286
            .::...|.|| ||.|    .:.:.|..|.  .:||...........|        ||..|..|:
 Worm   220 KKLLDDLAEYVNLEKALSQHKFNTVQPGY--IFSERSDFVSSVNFSRLVLEMMSPDKRTLFPEV- 281

  Fly   287 EVPRFGQWRSYYEIAW--NGIDFYNGSSGGEFCDFYYVELDKVCAKHT--EAVANYLAMRFLYRM 347
                       |:|.:  |...|:..::..|           ...::|  .|:||||..:|:
 Worm   282 -----------YQIMYLTNTSLFFGKNNNLE-----------TIIRNTSKRALANYLIFKFI--- 321

  Fly   348 DDKLKE-----PKQPEDQKVNCLMIVQMTLPNLFNRLYMAEHFTDEKHSEISDMVTEMRKAQ-RQ 406
            |..:.:     |....:|||...      ||....|.:.....:.|...:|:.: ||..:.| .:
 Worm   322 DTSIADLTYGSPSAFCEQKVINF------LPRAALRAFYRNFISKENRKKITKL-TEATQVQLLK 379

  Fly   407 ILESVEWLDAETRAEALSKEAGITPVIG---------------SYKNEELSD---TLIREINN-L 452
            |:.:.:|:..:::..|:.:.:.:..|||               .:.|...||   |::|:||. :
 Worm   380 IIGATDWMSIKSKKIAMDRVSSMNMVIGYPDYFDPPGKLDGLFEHLNLSSSDTYYTVVRKINRFM 444

  Fly   453 TIVEGSYAQSLINLRVLGTYLHRYAGLHADELPKDTKPLTLLVGMQVNAFYYNLDNSVYVMAGVL 517
            ...|..|                |.|    |:|.    ..|..|:..||.|...||::.:.|...
 Worm   445 REQEMDY----------------YTG----EVPY----YPLFPGLMTNAMYNANDNNLMIFAPFF 485

  Fly   518 HPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCYVDY 582
            ..|.:..|:||..........:.||:.|.|....... ..|....|.:.|....:::|.:|..|.
 Worm   486 DDPFFDSSFPDYANIAFTSNTLAHEMGHTFSPHLMDI-MTGTTEVWLTPKETEEYEKRVKCLEDQ 549

  Fly   583 FNQYLIPE 590
            :.:|..||
 Worm   550 YTEYDDPE 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	PepO	60..717	CDD:226118	126/590 (21%)
		M13	66..715	CDD:189000	124/584 (21%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	124/584 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920