Protein Alignment Nep7 and nep-6

DIOPT Version :9

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_494537.1
• Gene: nep-6 / 184628
• WormBaseID: WBGene00017550
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 691
• Identity: 171/691 - (24%)
• Similarity: 293/691 - (42%)
• Gaps: 110/691 - (15%)

  Fly    62 MNF---SVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVTEQLLTRTKLAEALNV- 122
            :||   |||||.|||:.|||.:    :..:..:||....||....|.....|...|..:::.||
 Worm    98 LNFQDPSVDPCQDFYKAACGKY----SEHEVANRRLQKKDIIIQRMIKNFLLKNETSESKSENVM 158

  Fly   123 -----SAELLVAQRFYNSCLAA---ELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWFNM 179
                 :.|.|..:..:|:.:..   |||          ..|:.:|.:||.|:: |:.:..:...|
 Worm   159 RQVYRTCEGLKNEEIFNANMKTAFRELF----------KDIQKIGSWPAADKN-WDETKLNLNEM 212

  Fly   180 SAHL-----SNYGVRSLIHEEILPQHPFNPYFKL-PEL--------GFDHVVH----------TA 220
            ..::     ||:|:..:...|:       |:.:: |::        .|..::.          ..
 Worm   213 LLNIVKLGSSNFGLFQIRPTEV-------PFLEVAPDMARSPKVSANFQQIIFDILEKNGLQPDE 270

  Fly   221 HVANTSSRAYQLNEHRMRGYLKEYNLTKDEISAVIEGVFAFWSEALSIEDKFESDRDKCDLLSEI 285
            :|.......|...|..:..|..:||..|.:.|.:...|.:...|.: ||:....:|.|. |::::
 Worm   271 NVIADDVEDYITLEETLSQYAYDYNAEKVQFSKLQAQVPSLKLEKI-IEEMMNPNRKKL-LVTKV 333

  Fly   286 EEVPRFGQWRSYYEIAWNGIDFYNGSSGGEFCDFYYVELDKVCAKHTEAVANYLAMRFLYRMDDK 350
            :  ||.        :|.....|::.....|       :|.|...|.|  :||||   ..|.||..
 Worm   334 K--PRM--------VAHKHSLFFDEKMNLE-------KLLKSTPKRT--LANYL---IFYYMDHA 376

  Fly   351 LKEPKQPED--QKVNCLMIVQMTLPNLFNRLYMAEHFTDEKHSEISDMVTEMRKAQRQILESVEW 413
            :......::  :|.||..:|...||....|:::..||.......:.:|..|.:|:..::|:...|
 Worm   377 MNGLSVHDNVIKKRNCEKLVIEYLPKASLRVFVRNHFEKGNLKIVDEMAEETKKSFIEMLQESTW 441

  Fly   414 LDAETRAEALSKEAGITPVIGSYKNEELSDTLIREINNLTIVEGSYAQSLINLRVLGTYLHRYAG 478
            |.|:::..|:.|...:..:||..|..|....|.:....|.::.......:  |:.:|.: |...|
 Worm   442 LGADSKKNAILKLEKMGKMIGYPKEFEKKGALDKMFETLKLLPKDTLYGI--LKKIGRF-HMEQG 503

  Fly   479 LH--ADELPKDTKPLTLLVGMQVNAFYYNLDNSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGH 541
            :.  |.|.|.|    .:|..:..||||.: .|.:..:.|.:..|.:..::|..:.....|.::.|
 Worm   504 IEFVALETPMD----PVLPVLMTNAFYTD-RNHLSFLVGYMDDPLFDATYPKYVNIALTGNILAH 563

  Fly   542 ELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCYVDYFNQYLIPEINQTIRGNETRDENIA 606
            |.:|||||.|...|..||||.|...:....:.::.||.||.:|:|..|...:.:.|..|.:|.:|
 Worm   564 ETSHGFDTAGIKRDENGEVRSWMKPEDLKEYGKKTQCLVDQYNEYDDPVFGKNLNGTTTLNEMVA 628

  Fly   607 DAGGLRAALTGYRNHMKQLQR--SGADGETLAHKNEQMPGLDLSPEQLFFVGFAQLWCADYEPEH 669
            |..|:..|       .|..::  |..:.:.:..:||.:       ::|:|...|..:|:......
 Worm   629 DMIGVTVA-------WKVFEKLDSSKEQKVIGFENENI-------DKLYFRAAALDFCSLPPTTS 679

  Fly   670 YWEELTGAHTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPK 710
            ..||||..|....:||.|..||...||..:.||.||||:||
 Worm   680 LVEELTRVHPTGNFRVNGIFSNMPQFATAFNCPEGSPMNPK 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	PepO	60..717	CDD:226118	171/691 (25%)
		M13	66..715	CDD:189000	168/684 (25%)
nep-6	NP_494537.1	M13	105..724	CDD:189000	168/684 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920