Protein Alignment Nep7 and nep-16

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001023203.2
• Gene: nep-16 / 177541
• WormBaseID: WBGene00018472
• Length: 868
• Species: Caenorhabditis elegans
• Alignment Length: 789
• Identity: 157/789 - (19%)
• Similarity: 277/789 - (35%)
• Gaps: 268/789 - (33%)

  Fly    11 PLYTRLAVC---------------------ILICVILNDCEARSIGDESHENAITDETADYLRSH 54
            |.|.|...|                     .|:.||..| ..|:||.:|.....|.:..|.
 Worm   183 PFYRRKGTCSKCSIWLGALCALFFLLSIALFLVWVITTD-GFRTIGAKSTNVCNTRQCIDI---- 242

  Fly    55 GAMMKSYMNFSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVTEQLLTRTKLAEA 119
            ...:.|.::..::||::||.::|..:.:....:|... .|.:.|.|...|   ..||:..:.:..
 Worm   243 AFRLSSCIDDEIEPCENFYRYSCQRYHSQTADKQMSF-LSQLKDESLRRM---HSLLSSEEDSRL 303

  Fly   120 LNVSAELLVAQRFYNSCLAAELFPRPAADPA-YLSVIRSLGGFPAVDRDAWN--ASSFSWFNMSA 181
            |..||.|  ::..|::|:.|.|  |.:..|. .|:.||:....|.: ||..|  |.|:||...:.
 Worm   304 LPKSARL--SRSLYSACMNAVL--RSSNAPTDLLTFIRNFPCGPLL-RDCQNFHADSYSWERHAG 363

  Fly   182 HLSNYGVR-SLI--HEEILPQH------PFNPYFKLPELGF--DHVVHTAHVANTSSRAYQLNEH 235
            .|..|..| :||  ..::.||.      ...|....|.:|.  ..::..|..:.|....
 Worm   364 MLDWYAGRYNLIVYDRDVHPQDRSKIILQIKPPDLTPIVGLIERDLIDLARPSPTEFEP------ 422

  Fly   236 RMRGYLKEYNLTKDEISAVIEGVFAFWSEALSIEDKFESDRDKCDLLSEIEEVPRF--------- 291
                 |.:.:|.::.:|       ||..::|.        ||..|:.|:::||.|.
 Worm   423 -----LLQLSLRQNLLS-------AFARDSLL--------RDPRDVQSQLDEVARLMVDLYISAR 467

  Fly   292 -------------------------------GQWRSYYEIAWNGIDFYNGSSGGEFCDF-YYVEL 324
                                           .|..:.|.  |...|..:      ..|: |:..|
 Worm   468 QSASLTPNTTYMTIGEMFQALPQLYLREFLDAQLSNTYR--WTETDMLS------IQDYDYFARL 524

  Fly   325 DKVCAKHT-EAVANYLAMRFLYRMDDKLKEPKQ----PEDQKVNCLMIVQMTLPNLFNRLYMAEH 384
            ..:.|:.: :||||||....::.:       ||    |.||......:.|::...:..::|:
 Worm   525 SDIMAQTSRQAVANYLLTVTVWNL-------KQYSYSPRDQYGWRECVDQISSFEIGRKMYV--- 579

  Fly   385 FTDEKHSEISDMVTEMRKAQRQILES--VEWLDAETRAEALSKEAGITPVIGSY-------KNEE 440
               :|.|:..|    :.|.| :.|::  :::|... |:..|...:.|.. :|.|       :|||
 Worm   580 ---DKASQTID----LPKIQ-EFLQNLKIDFLSVH-RSTPLQYLSNINR-LGFYVGFPRRLQNEE 634

  Fly   441 LSDTLIREINNLTIVEGSYAQSLI---------NLRVLGTYLHRYAGLHADELPKDTKPL---TL 493
            |   :.:.::.:::.|..|..|:|         .:..:||||        |.....|.|:   |:
 Worm   635 L---IWKPVSQVSLNETDYFDSMIRVGKAERDYTMSQIGTYL--------DNDDTTTFPISDPTM 688

  Fly   494 LVGMQVNAFYYNLDNSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHEL-THGFDTEGSSFDSA 557
            |....|.|        :.:....:.||.               ||.|.|: .:|.      :.|.
 Worm   689 LYNSNVGA--------IVIPLAFIEPPI---------------YLPGDEVPMYGI------YSSL 724

  Fly   558 GEV------RDWWSRKSEAVFQERAQCYVDYFNQYL----------IPEINQTIRGNETRDENIA 606
            |..      :.:|....:.   .:.:|..:.|..:|          .||:..||        .:|
 Worm   725 GITTLQMISKVFWQGLDKT---SQLECLDNVFRGFLDANRQRSPNIEPELLATI--------ELA 778

  Fly   607 DAGGLRAALTGYR-----NHMKQLQRSGADGETLAHKNEQMPGLDLSPE-QLFFVGFAQLWC--- 662
            ||  .::||..|.     :|:              |..:.:|..|.:.. :...:.|:.::|
 Worm   779 DA--FKSALYSYAKWQNDHHI--------------HHEKTLPAFDSTDSMRSLMLTFSTMFCSGE 827

  Fly   663 -----ADYE 666
                 :|||
 Worm   828 GSEPGSDYE 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	142/713 (20%)
nep-16	NP_001023203.2	GluZincin	254..>725	CDD:472708	118/573 (21%)