Protein Alignment Nep7 and nep-17

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001254395.1
• Gene: nep-17 / 174996
• WormBaseID: WBGene00010070
• Length: 1589
• Species: Caenorhabditis elegans
• Alignment Length: 801
• Identity: 184/801 - (22%)
• Similarity: 332/801 - (41%)
• Gaps: 195/801 - (24%)

  Fly    40 ENAITDETADYLRSHGAMMKSY---MNFSVDPCDDFYEFACGNWKNVKTPRQS----PHRRSNIL 97
            |..||....|.:.::...:..|   :|.::|||||||.:||||:      .||    ..|..|::
 Worm   855 EAPITSTNVDKMNAYQMAVDYYAKSVNTAIDPCDDFYSYACGNF------NQSVSFYTARAQNLV 913

  Fly    98 DISYTLMDVTEQLLTRTKLAEALNVSAELLVAQRFYNSCLAAELFPRPAADPAYLSV-------- 154
            .::..|.|.|.|        ..:|.|..|...::.||:||.|....: :.|...:|.
 Worm   914 YMAQKLEDPTYQ--------TTINSSPALKKEKQLYNACLTATASSQ-SEDQILISKNYIQTKVD 969

  Fly   155 -IRSL---------GGFPAVDR-----DAWNASSFSWFNMSAHLSNYGVRSLIHEEILPQHPFNP 204
             :::|         ||.|.:..     ||....||          ..|:.:||...:      :.
 Worm   970 DLKTLIGQDFTLVNGGAPKLPSAKQIGDALGYLSF----------EQGIDTLISPLV------DT 1018

  Fly   205 YFKLPELGFDHVV--HTAHVANT--SSRAYQLNEHR--------MRGYLKEYNLT-----KDEIS 252
            |:.....|:...:  :||:::.|  ...|:::.:.:        :..|.:|.|:|     .|.:|
 Worm  1019 YWIDNSKGYQMFIDQNTAYLSKTYYQPAAWKIEKPKYLKMALDVVTRYAREQNITLPAGASDLLS 1083

  Fly   253 AVIEGVFAFWSEALSIEDKFESDRD-------------KCDLLSEIEEVPRFGQWRSYYEIAWNG 304
            .|::     :.:.:::  |:.:|.:             ..||:::.    .|..|.:|...|.|.
 Worm  1084 NVLD-----YEQNIAV--KYSTDDNTRRQFQRSWNLTKTSDLVTKY----NFMDWMTYLSHAPNA 1137

  Fly   305 IDFYNGSSGGEFCDFYY----VELDKV-------CAKHTEAVANYLAMRFLYRMDDKLKEPKQPE 358
            :.       .:..|..|    :|:|::       ..:..|.:.|.|.:|.|  :.:....|....
 Worm  1138 VK-------AKITDANYQVSVMEVDRLTHFSADYLQQSPELLVNLLFVRLL--LGNAQYIPSYAS 1193

  Fly   359 ------DQKVNCLMIVQMTLPN------------------LFNRLYMAEH---FTDEKHSEISDM 396
                  |:.:...:..:.|:||                  :.|.|....:   |.|..:....|
 Worm  1194 AFRGMTDESIFLGLSRRKTIPNHIPPPNFDLEANGPACASVANNLMQFANGRVFVDYMYPTAQD- 1257

  Fly   397 VTEMRKAQRQILESV-----------EWLDAETRAEALSKEAGITPVIGSYKNEELSDTLI-REI 449
            ||.:||:...|:::|           :|:..:|:.:|.:|...|...| ::.:...:|||: ...
 Worm  1258 VTNIRKSAGGIIKNVISSFQGMIDQLDWMAPDTKQKAYAKTVQIQQNI-AFPDWIKNDTLLGNYY 1321

  Fly   450 NNLTIVEGSYAQSLINLRVLGTYLHRYAGLHADELPKDTKPLTLLVGM--QVNAFYYNLDNSVYV 512
            :.|.|.:......:.:..:......:|..|:|.:..:     |..:|.  .|||:|....||:..
 Worm  1322 STLVIADSDNFYDIYDKLIKFNIFVQYNQLNAAQTDR-----TDFLGQPGTVNAWYQPELNSITF 1381

  Fly   513 MAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQ 577
            .||:|.||.::.:||.|:.:|.:|.:.|||||||||.:|..:...|.:..|....|.|.|:..:|
 Worm  1382 PAGILVPPYFNPNWPPSINYGGMGLVAGHELTHGFDDQGVQWGPTGNLARWMDDNSMAGFKNMSQ 1446

  Fly   578 CYVDYFNQYLIPEINQT------IRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLA 636
            |.::.::.:.  .:|.|      ::|.:|:.|||||.||:.||...|:.|           ::|.
 Worm  1447 CVINEYSGFC--PLNATNYSPNCVKGPQTQGENIADNGGVHAAFNAYKTH-----------QSLD 1498

  Fly   637 HKNEQMPGL---DLSPEQLFFVGFAQLWCADYEPEH--YWEELTGAHTVDKYRVLGAVSNNDDFA 696
            ..:.::|..   ..:.:||||:.|||:||.....:.  |.:.:...|:...|||.|.:.|...|.
 Worm  1499 GPDPRLPDRLFGQFTHDQLFFMSFAQVWCEVRRTDDALYTQIMVDPHSPSMYRVYGTIQNFPAFQ 1563

  Fly   697 EVYKCPLGSPMHPKAESCRMW 717
            ..:.|||||...|: :.|.:|
 Worm  1564 TAFNCPLGSKSAPE-QHCEVW 1583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	176/768 (23%)
nep-17	NP_001254395.1	M13	112..831	CDD:341056
		M13	884..1581	CDD:341056	176/768 (23%)