Protein Alignment Nep7 and Mme

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_032630.2
• Gene: Mme / 17380
• MGIID: 97004
• Length: 750
• Species: Mus musculus
• Alignment Length: 786
• Identity: 202/786 - (25%)
• Similarity: 351/786 - (44%)
• Gaps: 140/786 - (17%)

  Fly    11 PLYTRLAVCILICVILNDCEARSIGDESHENAIT--------DE----TADYLRSHGAMMKSYMN 63
            ||...|:|.:|:..|:               |:|        |:    ::|.::|...:::: |:
Mouse    26 PLEISLSVLVLLLTII---------------AVTMIALYATYDDGICKSSDCIKSAARLIQN-MD 74

  Fly    64 FSVDPCDDFYEFACGNW--KNVKTPRQSPHRRSNIL--DISYTLMDVTEQLLTRTKLAEALNVSA 124
            .||:||.||:::|||.|  :||.....|.:...:||  ::...|.||.::..|...:|
Mouse    75 ASVEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVA------- 132

  Fly   125 ELLVAQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNAS-SFSWF---NMSAHLSN 185
             :..|:..|.||:...........| .|.::..:.|:| |..|.|:.: ..||.   :::...|.
Mouse   133 -VQKAKTLYRSCINESAIDSRGGQP-LLKLLPDIYGWP-VASDNWDQTYGTSWTAEKSIAQLNSK 194

  Fly   186 YGVRSLIH------EEILPQHPFNPYFKLPELGF---DHVVHTA--HVANTSSRAYQLNEHRMRG 239
            ||.:.||:      ::...||..  :|..|.||.   |:...|.  ..|.|:...:.::..|:..
Mouse   195 YGKKVLINFFVGTDDKNSTQHII--HFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIR 257

  Fly   240 YLKEYNLTKDEISAVIEGVFAFWSEALSIEDKFESDRDKCDLLSEIEEVPRFGQWRSYYEIAWNG 304
            ..:...:.::::|..:..|.....|..:...|.|...|...|.:::    ...:.::.:.:..||
Mouse   258 QEQSLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKM----TLAKLQNNFSLEVNG 318

  Fly   305 -----------------IDFYNGSSGGEFCDFYYVELDKVCAKHT-EAVANYLAMRFLYRMDDKL 351
                             |:..|......:...|..:|..:..|:: ..:.|.::.||:..:...|
Mouse   319 KSFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSL 383

  Fly   352 ----KEPKQPEDQKV-----------NCLMIVQMTLPNLFNRLYMAEHFTDEKHSEISDMVTEMR 401
                ||.:....:.:           .|...|...:.|...|||:...|..|....:.|::.::|
Mouse   384 SRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIR 448

  Fly   402 KAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKNEELSDTLIREINN----LTIVEGSYAQS 462
            :...|.|:.:.|:||||:.:|..|...|...|| |.::.:|:.  .::||    |...|..|.::
Mouse   449 EVFIQTLDDLTWMDAETKKKAEEKALAIKERIG-YPDDIISNE--NKLNNEYLELNYREDEYFEN 510

  Fly   463 LI-NLRVLGTYLHRYAGLHADELPKDTKPLTLLVGMQ--------VNAFYYNLDNSVYVMAGVLH 518
            :| ||:.              ...|..|.|...|...        |||||.:..|.:...||:|.
Mouse   511 IIQNLKF--------------SQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQ 561

  Fly   519 PPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCYV-DY 582
            ||.:.....:||.:|.||.:||||:|||||..|.:|:..|::.|||:::|...|::::||.| .|
Mouse   562 PPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQY 626

  Fly   583 FNQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNEQMPGLDL 647
            .|........|.:.|..|..|||||.||:..|...|:|::|:      :||     .:.:|||||
Mouse   627 GNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKK------NGE-----EKLLPGLDL 680

  Fly   648 SPEQLFFVGFAQLWCADYEPEHYWEEL-TGAHTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPKA 711
            :.:||||:.|||:||..|.||:....: |..|:...:|::|.:.|:.:||:.:.|...|.|:|:
Mouse   681 NHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPE- 744

  Fly   712 ESCRMW 717
            ..||:|
Mouse   745 RKCRVW 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	186/715 (26%)
Mme	NP_032630.2	Stop-transfer sequence. /evidence=ECO:0000255	16..23
		M13	77..748	CDD:341056	186/715 (26%)