Protein Alignment Nep7 and nep-9

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 737
• Identity: 159/737 - (21%)
• Similarity: 280/737 - (37%)
• Gaps: 189/737 - (25%)

  Fly    58 MKSYMNFSVDPCDDFYEFACGNWKN---VKTPRQSPHRRS-NILDISYTLMDVTEQLLTRTKLAE 118
            :|:|.:.:...|:|||:..|.|:|:   :...|....|:: |.|...:...|.:    |.|..:|
 Worm    76 LKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKAVNKLVRGFLQRDES----TFTSESE 136

  Fly   119 ALNVSAELLVAQRFYNSCLAAELFPRPAADPAYLSV---IRSLGGFPAVDRDAWNASSFSWFNMS 180
                ||..|:    :..|  .||    :.:.:||.:   |:.:|.:|.::.: |..|.|:..::.
 Worm   137 ----SAIKLI----FGKC--DEL----SRNTSYLDIFKDIKKIGSWPVLEHN-WKDSMFNLDDVI 186

  Fly   181 AHL-----SNYGVRSLIHEEILPQHPFNPYFKLPELGFDHVVHTAHVANTSSRAYQLNEHRMR-- 238
            |.|     :::|:..|               :|.:|.|.|     .....||:..| |.|::.
 Worm   187 AKLVKLGSTDFGLFKL---------------ELRKLAFGH-----FAVFVSSKQEQ-NIHQLEKT 230

  Fly   239 --GYLKEYNLTKD--EISAVIEGVFAFWSEALSIEDKFESDRDKCDLLSEIEEVPRFGQWRSYYE 299
              |.||...:.:|  |:|                    :..:|..|..:.::|   |.|..:|.|
 Worm   231 ILGILKANGIQQDRKELS--------------------DDLKDYSDFKNHLKE---FYQEETYIE 272

  Fly   300 ----------------------IAWNGIDFYN---------GSSGGEFCDFYYVE---LDKVCAK 330
                                  :...|:|.:|         .||      .::.|   |..:..|
 Worm   273 YRLYAGSIVENLGISSLTTQMALKSTGLDVFNHVNQRTLITNSS------LFFGEENNLGMIIQK 331

  Fly   331 HTE-AVANYLAMRFLYRMDDKLKEPKQPEDQKVNCLMIVQMTLPNLFNRL---YMAEHFTDEKHS 391
            ..: .:||:|...|:..|...|          .|.....:.||.:|..|.   .::.:|.:|...
 Worm   332 TPKRTLANFLIFHFIDVMTTDL----------ANATKACKETLIDLLPRASIQVLSRNFVNEDAQ 386

  Fly   392 EISDMVTEMRKAQRQILESVE----------WLDAETRAEALSKEAGITPVIGSYKNEELSDTLI 446
            :  |||...:..:.:|.|.::          ..|||.:.:.:.|...| .::..|..|.|....
 Worm   387 D--DMVKMAQDLKTKITEMIDNSPFFTKFHLVFDAEEQKKLIQKVKAI-GIVTEYPQEVLDRDF- 447

  Fly   447 REINNLTIVEGSY--AQSLINLRVLGTYLHRYAGLHADELPKDTKPLTLLVGMQVNAFYYNLDNS 509
             |..|||..:..|  .|.|..||......|    |..|..|.||:       :..:|.|....|:
 Worm   448 -ERLNLTPSDSIYRTIQKLRRLRSEQLIEH----LGGDLDPTDTR-------VWGSAHYDQTTNN 500

  Fly   510 VYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQE 574
            :.:.|.::..|.:..|:|:.:....:|:::|.||....|:.....|..|:..:|...:|...|.|
 Worm   501 LTIFAPIIDGPYFDTSYPNYVNQFLMGFILGRELGRSLDSVRIRKDEKGQTENWLKPESLKRFDE 565

  Fly   575 RAQCYVDYFNQYLIPEINQT-----IRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGET 634
            ..:|:.:.:::...|..:::     |.|...::|..||..|..|:   :|..||
 Worm   566 HLKCWAEKYDKSADPLKSESKGIRQIEGRYIQNEMFADFIGHEAS---WRAFMK----------- 616

  Fly   635 LAHKNEQMPGLD----LSPEQLFFVGFAQLWCADYEPEHYWEELTGAHTVDKYRVLGAVSNNDDF 695
            |..|||::  |:    :...::||...|..:|........|......|....:||.||..|...|
 Worm   617 LDVKNEEV--LETFKVIKLRRMFFNVQALYFCRPPSGSTDWLSYQEHHQHYSFRVNGAFKNMPQF 679

  Fly   696 AEVYKCPLGSPMHPKAESCRMW 717
            |..::|.....|:|: ..|.|:
 Worm   680 ALAFECASDDDMNPQ-NKCSMF 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	155/725 (21%)
nep-9	NP_494531.2	GluZincin	87..698	CDD:472708	155/722 (21%)