Protein Alignment Nep7 and Nep1

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_553645.4
• Gene: Nep1 / 1279203
• VectorBaseID: AGAMI1_011171
• Length: 869
• Species: Anopheles gambiae
• Alignment Length: 790
• Identity: 217/790 - (27%)
• Similarity: 357/790 - (45%)
• Gaps: 127/790 - (16%)

  Fly     4 ISSYFRLPLY---TRLAVCILICVIL-------------NDCEA-------RSIGDESHENA--- 42
            :|:.|..|..   |.|.|.|.:.::|             :.|.|       ..:.|||..::
Mosquito   131 LSAAFARPTVLGGTMLLVGIALGILLVYLVGRYRQLDGKSGCSADPFAPGCPDVTDESRRSSNIC 195

  Fly    43 ITDETADYLRSHGAMMKSYMNFSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVT 107
            :|||.   :|:..:::.: |:.:.|||.||::||||.|..:..   .|..||:|  .::.::...
Mosquito   196 LTDEC---VRTASSLLAA-MDRTADPCKDFFQFACGTWNKMHV---IPEDRSSI--STFEVLADQ 251

  Fly   108 EQLLTRTKLAEALNVSAELLV--AQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWN 170
            :|.:.:..|.|.:|.......  |:.||.||:..|.. |.....|....::.|||:|.:::: |.
Mosquito   252 QQAILKGVLEEPVNKEDNRATKKAKAFYKSCMNLEQI-RLLDVQALRKSLKKLGGWPVIEKN-WT 314

  Fly   171 ASSFSWFNMSAHLS-NYGVRSLIHEEILPQHPFNPYFKLPELGFDHVVHTAHVANTS-------S 227
            ..|.|..::...|: .|....|:...:               |.|....:.::....       |
Mosquito   315 VPSTSIEHLLGKLTGEYDEPGLVELYV---------------GADDKNSSMNIIQVDQLLLALPS 364

  Fly   228 RAYQLNEHRMRGYLKEYN-----------LTKDEISAVIEGVFAFWSEALSIEDKFESDR-DKCD 280
            |.|.|.| ...|.:|.|:           ..||:.:..::.:..| ...|:.....|:|| |...
Mosquito   365 RDYYLKE-SSEGDMKAYHRYMTQIAILMGADKDKAAEELQRIVEF-EVRLANATLPEADRHDTSA 427

  Fly   281 LLSEI------EEVPRFGQWRSYYEIAWNGIDFYNGSSGGEFCDFYYVELDKVCAKHTE--AVAN 337
            :.::|      ..||:. .|:.|.:.....:..:...|...:...|.|||.|: .:.|:  .|.|
Mosquito   428 IYTKITLPELQRRVPQI-NWKEYLQTTLGTVALHPNESIVSYAMPYLVELGKI-LRDTDRRIVHN 490

  Fly   338 YLAMRFL-----YRMDDKLKEP----------KQPEDQKVNCLMIVQMTLPNLFNRLYMAEHFTD 387
            |...|.:     :.:||..||.          :...::...|:......|......|::.::|..
Mosquito   491 YAIWRLVMSIMTHMIDDYQKERVEFRRKLLGIQSERNRWSQCVEWTNKKLGMAVGALFIRDNFNQ 555

  Fly   388 EKHSEISDMVTEMRKAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKNEELSDTLIREINNL 452
            |.......|:..:|:|..::|..::|:|.||||.|..|...:...||.......:|.|.:|..||
Mosquito   556 ESKETALTMIHTIREAFNELLADIDWMDDETRAVAKEKADAMNERIGYPDILTNADELEKEYVNL 620

  Fly   453 TIVEGSYAQSLINLRVLGTYLHRYAGLHADELPKD---TKPLTLLVGMQVNAFYYNLDNSVYVMA 514
            ||..|.:.:::  |.:|.....|...|....:.|:   |:|..      |||||....|.:...|
Mosquito   621 TIHGGLFLENI--LSILKWEAERNLQLLRKPVDKNKWATEPAV------VNAFYNPNKNDIVFPA 677

  Fly   515 GVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCY 579
            |:|.|..|.:::|.||.:|.||.:||||:|||||.:|..||..|.:..||:..:...|:|||||.
Mosquito   678 GILQPLFYSQNFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKDGNMMQWWNNATIKTFRERAQCI 742

  Fly   580 VDYFNQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNE-QMP 643
            :|.:::|.|.|:...:.|..|:.|||||.|||:.:...||..:.|            |.:| .:|
Mosquito   743 IDQYSRYKIDEVGLYMDGRMTQGENIADNGGLKQSYRAYRKWVSQ------------HGSEPDLP 795

  Fly   644 GLDLSPEQLFFVGFAQLWCADYEPEHYWEEL-TGAHTVDKYRVLGAVSNNDDFAEVYKCPLGSPM 707
            ||:::.:||||:.:||:||....||....:: :..|:....||:|.:||:.||||.|:|||||||
Mosquito   796 GLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSSVHSPGIIRVIGPLSNSRDFAEAYRCPLGSPM 860

  Fly   708 HPKAESCRMW 717
            :| ...|.:|
Mosquito   861 NP-VSKCSVW 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	197/698 (28%)
Nep1	XP_553645.4	None