Protein Alignment Nep7 and Nep3

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_317711.2
• Gene: Nep3 / 1278166
• VectorBaseID: AGAMI1_011685
• Length: 789
• Species: Anopheles gambiae
• Alignment Length: 807
• Identity: 202/807 - (25%)
• Similarity: 339/807 - (42%)
• Gaps: 176/807 - (21%)

  Fly    12 LYTRLAVCILICVILNDCEARS----------IGDESHENAITDETADYLRSHGAMMKS----YM 62
            |.:.||:.|::.|:|:...|..          :|.:...   .||....|..|.....|    .:
Mosquito    58 LLSLLALSIILIVVLSSLLASDTTRILHVRPHVGSDPFG---VDEQLPCLNQHCIFAASEILHSI 119

  Fly    63 NFSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVTEQLLTRTKLAEAL---NVSA 124
            ::|||||||||.|:|..|     .|.:|......:...:..::...||:.:..|...|   ...|
Mosquito   120 DWSVDPCDDFYAFSCNQW-----IRNNPIPEGKSMWGLFGKLEQQNQLVLKNALERPLAEFKSKA 179

  Fly   125 ELLVAQRFYNSCL-AAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSFSWFNMSAHLSNYGV 188
            | ..|:.:|.||| ..|...:..|:|.. .::|.:||               | |::|:.|.:.|
Mosquito   180 E-KKAKLYYQSCLDEDETMEKLGAEPLQ-KLLRQIGG---------------W-NVTANASGFDV 226

  Fly   189 RSLIHEEILP----QHPFNPYFKLPELGFDHVVHTAHVANTS-------SRAYQLNEHR----MR 238
            :....:..|.    ::.....|.. .:|.|....:.|:....       ||...||:..    :.
Mosquito   227 QRWSLQRTLQTLQIRYNMGGLFGW-AVGEDDRNSSKHIIQIDQGGLTLPSRDNYLNKTANAKILT 290

  Fly   239 GYLKEYNLTK-------DEISA---VIEGVFAFWSEALSIEDKFESDRDKCDL-----LSEIEEV 288
            .|| || :||       ||..|   ::| |..|.:...:|....:..||:..|     |:.::|.
Mosquito   291 AYL-EY-MTKVSVLLGADETDARRQMLE-VIEFETRLANITTPQDMRRDEETLYHPMTLAMLQEK 352

  Fly   289 PRFGQWRSYYEIAWNGIDFYNGSSGGEFCDFYYVELDKVCAKHTEAVANYLAMRFLYRMDDKLKE 353
            ..|..|:.::|.|                  :.:...|:..|  |.|..| |..:|.:::..:||
Mosquito   353 APFINWQEHFEEA------------------FRLVRRKITEK--ERVVVY-APEYLEKLNILMKE 396

  Fly   354 PKQPEDQKV--------------------------------------------NCLMIVQMTLPN 374
            ....:::|:                                            .|:......|..
Mosquito   397 YTSTDEKKIILNNYLVWQTVRTLTACLSKAFRDAYKGLRKALMGSDGGEELWRYCVSDTSNVLGF 461

  Fly   375 LFNRLYMAEHFTDEKHSEISDMVTEMRKAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKNE 439
            ....:::.:.|..:...:..:|:.::|.|.::..:::.|:|||||..|:.|...|:.:||.....
Mosquito   462 AVGAMFVRDVFHGDSKPQAEEMINQVRDAFKENFKNLGWMDAETRRLAVEKADAISDMIGFPDYI 526

  Fly   440 ELSDTLIREINNLTIVEGSYAQSLINLRVLGTYLHRYAGLHADELPKDTKPLTLLV-----GM-- 497
            ...:.|.|:..:|.|...:|..:.||..:.             .|.|:.:.|...|     ||
Mosquito   527 LYPEELDRKYQDLNIDPKTYFDNNINYNIY-------------SLKKNLEKLDQPVNKTKWGMTP 578

  Fly   498 -QVNAFYYNLDNSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVR 561
             .|||:|....|.:...||:|..|.:......||.:|.:|.::||||||.||.:|..:|..|.:.
Mosquito   579 PTVNAYYTPTKNQIVFPAGILQNPFFDIKNSKSLNYGAMGVVMGHELTHAFDDQGREYDKYGNLH 643

  Fly   562 DWWSRKSEAVFQERAQCYVDYFNQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQ 626
            .||:.::...|:.:.:|:...::.|.|.  .:||.|.:|..|||||.|||:||...|.|:.|
Mosquito   644 QWWNNQTIERFKNQTECFNQQYSAYRIN--GKTINGKQTMGENIADNGGLKAAFHAYINNEK--- 703

  Fly   627 RSGADGETLAHKNEQMPGLDLSPEQLFFVGFAQLWCADYEPEHYWEEL-TGAHTVDKYRVLGAVS 690
            .|..|.:||     .:||::::..|||||.|||:||:....|....:: ..:|:..||||:|.:|
Mosquito   704 NSYTDTDTL-----PLPGVNMTHRQLFFVSFAQVWCSAVTDETTTLQIEKDSHSPPKYRVIGPLS 763

  Fly   691 NNDDFAEVYKCPLGSPMHPKAESCRMW 717
            |..:|::.:.||||:.|:| .|.|.:|
Mosquito   764 NLKEFSDTFHCPLGTGMNP-IEKCVVW 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	186/735 (25%)
Nep3	XP_317711.2	None