Protein Alignment Nep7 and Nep4

DIOPT Version :10

• Sequence 1: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_061501026.1
• Gene: Nep4 / 1273777
• VectorBaseID: AGAMI1_013990
• Length: 1007
• Species: Anopheles gambiae
• Alignment Length: 862
• Identity: 225/862 - (26%)
• Similarity: 348/862 - (40%)
• Gaps: 221/862 - (25%)

  Fly    24 VILNDCEARSIGDESHENAITD---ETADYL----RSHG-----------------AMMKSYMNF 64
            |:..||    :|:::..:..|:   |.::.|    ||.|                 |:||.||:.
Mosquito   199 VLPADC----LGEQAQPSTATEKAVERSEQLPRVRRSVGWMNDDRSSPESVRAAQVAIMKQYMDP 259

  Fly    65 SVDPCDDFYEFACGNWKNVK-TPRQSPH-------RRS---------------NILDISYTLMDV 106
            ..|||||||::|||||..|. .|:....       |.|               .:||:...|..|
Mosquito   260 DADPCDDFYQYACGNWDRVNPIPKDKAALDTFELLRESLDLVLKQLLLEGEPAGLLDVENALSTV 324

  Fly   107 TEQ-------------------------------------------------------LLTRTKL 116
            ..|                                                       |:.|:..
Mosquito   325 RSQPDGTKKSTSTTTTAASAGWPTTTVTGGPAQQQLHRVRKRGRAENRNRSGRAVQNKLIIRSAQ 389

  Fly   117 AEALNVSAELLV-------AQRFYNSCLAAELFPRPAADPAYLSVIRSLGGFPAVDRDAWNASSF 174
            .:.:....|||:       |:..:.||:..||..|...:| ..:::.||||:|.::...|:.|||
Mosquito   390 VKRVRRKRELLINDDAEMKARHLFVSCMNYELIERRGLEP-LRTLLHSLGGWPVLEPHTWDESSF 453

  Fly   175 SWFNMSAHLSNYGVRSLIHEEILPQHPFNPYFKLPELGFDHVVHTAHVANTSSRAYQLNEHRM-- 237
            .|.|::|.|..|....||.|.:.|.                      :.|:.....|.::..:
Mosquito   454 DWLNLTAALRRYNNDVLIVEWVGPD----------------------IKNSDENIVQFDQTSLGL 496

  Fly   238 -----------RGYLKEY-----------NLTKDEISAVIEGVFAFWSEALSIEDKFESDRDKCD 280
                       |.||:.|           ::..|......:.:..|.::..:|....|...:...
Mosquito   497 PTRDYYLQPGNRKYLEAYRQFMLEVIGLLDVPADTARQATDEMIEFETQLANITSTPEERNNVST 561

  Fly   281 LLSEI------EEVPRFGQWRSYYEIAWNGIDFYNGSSGGEFCDFYYVE--LDKVCAKHTEAVAN 337
            |..::      ||||:. .|..|..|.....  .||||........|:.  ::.:.......|||
Mosquito   562 LYRKLMLDQLQEEVPQI-NWTHYLTIVTERP--VNGSSFVVMFAMSYMRDLVELIDQTEPRIVAN 623

  Fly   338 YLAMRF----LYRMDDKLKEPKQ------------PEDQKVNCLMIVQMTLPNLFNRLYMAEHFT 386
            ||..||    :..:||:....||            |...| ||:..|...:......:::..:|.
Mosquito   624 YLLWRFVRHRINNLDDRFLGAKQRFSNALFGRERNPPRWK-NCVTQVNANMGMAVGAMFVRRYFD 687

  Fly   387 DEKHSEISDMVTEMRKAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKN-----EELSDTLI 446
            :....:...|..|::.|.|:||....|:|..||..|..|...::..|| |.:     |:||
Mosquito   688 ENSKRDTLTMTHELQDAFREILGRTGWIDMATRQLAEQKVNAMSLRIG-YPDFILDPEQLS---- 747

  Fly   447 REINNLTIVEGSYAQSLINLRVLGTYLHR----YAGLHADELPKDTKPLTLLVGMQVNAFYYNLD 507
            .....|.|....|.::.:|:.   :::.|    ..|...::....|.|..      |||:|....
Mosquito   748 ARYATLEIHPDRYFENTLNVL---SHIRRTDQEKLGQPVNKTAWHTAPAV------VNAYYSRNK 803

  Fly   508 NSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVF 572
            |.:...||:|.||.|||..|.::.:|.||.:||||||||||.:|..||..|.:..|||.::...|
Mosquito   804 NQIMFPAGILQPPFYHRHLPKAINYGGIGVVIGHELTHGFDDKGRLFDRDGNLYRWWSDRAIEEF 868

  Fly   573 QERAQCYVDYFNQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHM-KQLQRSGADGETLA 636
            .|||.|.|:.:.:|.|.|::..:.|..|:.|||||.||::.|...|...: .|..|...:.|||
Mosquito   869 HERAACLVEQYGRYRIAEVDVQLDGENTQGENIADNGGIKQAFLAYSKWLAAQTDRRVLEAETL- 932

  Fly   637 HKNEQMPGLDLSPEQLFFVGFAQLWCADYEPEHYWEEL-TGAHTVDKYRVLGAVSNNDDFAEVYK 700
                  |||:::..||||:.|||:||....||....:| |..|:..::||:|.:||::|||..|.
Mosquito   933 ------PGLNVTRTQLFFLNFAQIWCGAMRPEATRNKLKTAVHSPGRFRVIGTLSNSEDFAREYH 991

  Fly   701 CPLGSPMHPKAESCRMW 717
            ||:||.|:|..: |.:|
Mosquito   992 CPVGSTMNPPGK-CSVW 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep7	NP_651603.1	M13	66..715	CDD:341056	208/792 (26%)
Nep4	XP_061501026.1	None