Protein Alignment Gp93 and trap1

DIOPT Version :10

• Sequence 1: NP_651601.1
• Gene: Gp93 / 43354
• FlyBaseID: FBgn0039562
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001107097.1
• Gene: trap1 / 571959
• ZFINID: ZDB-GENE-030131-4257
• Length: 719
• Species: Danio rerio
• Alignment Length: 723
• Identity: 216/723 - (29%)
• Similarity: 376/723 - (52%)
• Gaps: 101/723 - (13%)

  Fly    43 TDAETLKREEEAIQLDGLN-VAQLKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISN 106
            |...|...|||.:.    | :...:.::....|..||.|..:::.::..|||..||:|:||||||
Zfish    74 TQQHTEPAEEETLH----NIITDTENVQGSFSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN 134

  Fly   107 ASDAIDKIRLLALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTA 171
            .|||::|:|...::...  :|.| :.|.::.|.......|.|:|:||..:||::||||||:||:.
Zfish   135 GSDALEKLRHRMITAGG--DTAP-MEIHLQTDSVKGTFTIQDTGVGMNKEDLVSNLGTIARSGSK 196

  Fly   172 DFLAKMQDPSKSEGLDMNDMIGQFGVGFYSAFLVADRVVVTTK--HNDDKQYIWESDANS-FSIT 233
            .||..:|:.:::.    :.:||||||||||||:|||:|.|.::  ..|...|.|.||.:. |.:.
Zfish   197 AFLDALQNQAEAS----SSIIGQFGVGFYSAFMVADKVEVYSQSAEADAPGYKWSSDGSGVFEVA 257

  Fly   234 EDPRGDTLKRGSVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRMWSSKTVEEEVPVEEEAK 298
            |   ...:::|:.|.|:||::.::|..||.|:|::.|||.|::|||.:...:
Zfish   258 E---ASGVRQGTKIVLHLKDDCKEFSSEDRVKEVVTKYSNFVSFPIFLNGRR------------- 306

  Fly   299 PEKSEDDVEDEDAKVEEAEDEKPKTKKVSKTTWDWTLINDSKPIWTRKPAEVTEDEYTSFYKSLT 363
                                                 :|..:.:|..:|.:::|.::..||:.:.
Zfish   307 -------------------------------------LNTLQALWMMEPKDISEWQHEEFYRYVA 334

  Fly   364 KDSSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNY 428
            :...:|....|:.|:..:..:|:.|||:::|| .|:.......::.||.|::.|..:..|::|.:
Zfish   335 QAYDKPRYTLHYRADAPLNIRSIFYVPEMKPS-MFDVSREMGSSVALYSRKILIQTKATDILPKW 398

  Fly   429 LSFIRGVVDSDDLPLNVSRETLQQHKLIK----VIKKKLVRKVLDMLKKIDKEAYEKFWKEFSTN 489
            |.|:||||||:|:|||:|||.||:..||:    |::::::|.:||..|| |.|.|.:|::::...
Zfish   399 LRFLRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRVIRFLLDQSKK-DPEKYARFFEDYGLF 462

  Fly   490 IKLGVME--DPSNRSRLAKLLRFQTS---NGKGVTSLAEYKERMKAKQEHIYYIAGANRAEVEKS 549
            ::.|::.  :.|.:..:||||||::|   .|: .|||.||..||||...:|||:...||...|.|
Zfish   463 MREGIVTTGEQSVKEDIAKLLRFESSALPAGQ-QTSLMEYSSRMKAGTRNIYYLCAPNRHLAEHS 526

  Fly   550 PFVERLLSKGYEVLYLVEAVDEYCISALPEFDGKKF----QNVAKEGFQLNESEKSKKNFESLKS 610
            |:.|.:..|..|||:..|..||..:..|.|||.||.    .::..:.::..:.:.||...|.|.|
Zfish   527 PYFEAMKQKDMEVLFCFEQFDELTLLHLREFDRKKLISAETDIVVDHYKEEKFQDSKPASERLSS 591

  Fly   611 -TFEPLVKWLNDVALKDQISKAQVSERLSNSPCALVAGVFGWTGNM---ERLAMSNAHQKSDDPQ 671
             ..|.|:.|:.: ||..:::..:|:.||...|..:.....|...:.   ::||.|:       .:
Zfish   592 EQAEDLLAWMRN-ALVQRVTNIKVTPRLDTHPAMITVLEMGAARHFLRTQQLARSS-------EE 648

  Fly   672 RTYYLNQKKTLEINPRHPLMRELLRRVEADEADDTAKDMAVMMFRTATLRSGYMLQETSQFADSI 736
            |...|  :.|||||..|.|:::|  ....|...:.|:.:...::..|.:.:| :.::.......:
Zfish   649 RAQIL--QPTLEINTGHDLIKKL--HALKDSNPELAQLLLEQIYDNAMIAAG-LNEDPRPMISRL 708

  Fly   737 EQMMRQTL 744
            .|::.:.|
Zfish   709 NQLLTRAL 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp93	NP_651601.1	HATPase_Hsp90-like	82..275	CDD:340404	76/195 (39%)
		HSP90	257..748	CDD:459703	138/505 (27%)
trap1	NP_001107097.1	PRK05218	102..717	CDD:235366	210/691 (30%)