Protein Alignment Gp93 and hsp90aa1.1

DIOPT Version :9

• Sequence 1: NP_651601.1
• Gene: Gp93 / 43354
• FlyBaseID: FBgn0039562
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001016282.1
• Gene: hsp90aa1.1 / 549036
• XenbaseID: XB-GENE-495303
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 753
• Identity: 336/753 - (44%)
• Similarity: 492/753 - (65%)
• Gaps: 45/753 - (5%)

  Fly    53 EAIQLDGLNVAQLKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLL 117
            |.:|    ...|.:::.|..:.|.||.|:.::|.||||:.|.||||||||||||:|||:||||..
 Frog     3 EEVQ----TTTQDQQMEEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYE 63

  Fly   118 ALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSK 182
            :|::..:|::..||.|.:..:|:::.|.|:|:|||||..||||||||||||||..|:..:|
 Frog    64 SLTDPSKLDSGKELKIYLIPNKQDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQ---- 124

  Fly   183 SEGLDMNDMIGQFGVGFYSAFLVADRVVVTTKHNDDKQYIWESDA-NSFSITEDPRGDTLKRGSV 246
             .|.|:: ||||||||||||:|||::|.|.||||||:||.|||.| .||::..| .|:.|.||:.
 Frog   125 -AGADIS-MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVD-NGEPLGRGTK 186

  Fly   247 ISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRMWSSKTVEEEVPVE--EEAKPEKSEDDVEDE 309
            :.|||||:..::.||..::|.::|:||||.:||.::..|..::|:..:  ||.|.||.|:..::|
 Frog   187 VILYLKEDQSEYFEEKRIKETVKKHSQFIGYPITLFVEKERDKEISDDEAEEEKEEKKEEAKDEE 251

  Fly   310 DAKVEEA---------EDEKPKTKKVSKTTWDWTLINDSKPIWTRKPAEVTEDEYTSFYKSLTKD 365
            ..::|:.         |.:|.|.||:.:...|...:|.:||||||.|.::|.:||..||||||.|
 Frog   252 KPEIEDVGSDEEDDKKEGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTND 316

  Fly   366 SSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESF-NRYGTKSDNIKLYVRRVFITDEFNDMMPNYL 429
            ..:.|...||..||::.|::||:||:..|.:.| ||  .|.:|||||||||||.|...:::|.||
 Frog   317 WEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENR--KKKNNIKLYVRRVFIMDNCEELIPEYL 379

  Fly   430 SFIRGVVDSDDLPLNVSRETLQQHKLIKVIKKKLVRKVLDMLKKI--DKEAYEKFWKEFSTNIKL 492
            :||||||||:|||||:|||.|||.|::|||:|.||:|.|::..::  |||.|:||:::||.||||
 Frog   380 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKFYEQFSKNIKL 444

  Fly   493 GVMEDPSNRSRLAKLLRFQTS-NGKGVTSLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLL 556
            |:.||..||::|::|||:.|| :|..:.||.:|..|||..|:|||||.|..:.:|..|.|||||.
 Frog   445 GIHEDSQNRNKLSELLRYYTSASGDEMVSLKDYCTRMKESQKHIYYITGETKEQVAHSAFVERLR 509

  Fly   557 SKGYEVLYLVEAVDEYCISALPEFDGKKFQNVAKEGFQLNESEKSKKNFESLKSTFEPLVKWLND 621
            ..|.||:|::|.:||||:..|.||:||...:|.|||.:|.|.|:.||..|..||.||.|.|.:.|
 Frog   510 KHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKSKFENLCKIMKD 574

  Fly   622 VALKDQISKAQVSERLSNSPCALVAGVFGWTGNMERLAMSNAHQKSDDPQRTYYLNQKKTLEINP 686
            : |:.::.|..||.||..|||.:|...:|||.||||:..:.|.:   |.....|:..||.|||||
 Frog   575 I-LEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALR---DNSTMGYMAAKKHLEINP 635

  Fly   687 RHPLMRELLRRVEADEADDTAKDMAVMMFRTATLRSGYMLQETSQFADSIEQMMRQTLGVSQDEQ 751
            .|.::..|.::.::|:.|.:.||:.:::|.||.|.||:.|::....|:.|.:|::..||:
 Frog   636 DHSIIETLRQKADSDKNDKSVKDLVILLFETALLSSGFSLEDPQTHANRIYRMIKLGLGI----- 695

  Fly   752 VEFDEEEEDDAEE--TATGSQESGNADDEEEEQQHDEL 787
                 :|:|.|.|  :|..::|....:.:|:..:.:|:
 Frog   696 -----DEDDTATEDLSAPATEEMPPLEGDEDSSRMEEV 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp93	NP_651601.1	PRK05218	74..745	CDD:235366	322/686 (47%)
		HATPase_c	97..216	CDD:238030	68/118 (58%)
		HSP90	257..748	CDD:278607	222/505 (44%)
hsp90aa1.1	NP_001016282.1	PTZ00272	19..729	CDD:240341	332/733 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D174605at33208
OrthoFinder	1	1.000	-	-		FOG0000295
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X234
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920