Protein Alignment Gp93 and Trap1

DIOPT Version :10

• Sequence 1: NP_651601.1
• Gene: Gp93 / 43354
• FlyBaseID: FBgn0039562
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001034090.1
• Gene: Trap1 / 287069
• RGDID: 1359733
• Length: 706
• Species: Rattus norvegicus
• Alignment Length: 715
• Identity: 216/715 - (30%)
• Similarity: 368/715 - (51%)
• Gaps: 127/715 - (17%)

  Fly    43 TDAETLKREEEAIQLDGLNVAQLKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISNA 107
            |.|...|:||....:    ::..:.::....|..||.|..:::.::..|||..||:|:|||||||
  Rat    62 TQAAEDKKEEALHSI----ISNTEAVQGSVSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA 122

  Fly   108 SDAIDKIRLLALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTAD 172
            |||::|:|...:...:.|   ||:.|.::.|.|...:.|.|:|||||.::|::||||||:||:..
  Rat   123 SDALEKLRHKRVCEGQVL---PEMEIHLQTDAEKGTITIQDTGIGMTKEELVSNLGTIARSGSKA 184

  Fly   173 FLAKMQDPSKSEGLDMNDMIGQFGVGFYSAFLVADRVVVTTK--HNDDKQYIWESDANS-FSITE 234
            ||..:|..:::.    :.:||||||||||||:|||:|.|.::  ..:...|.|.||.:. |.|.|
  Rat   185 FLEALQHQAETS----SRIIGQFGVGFYSAFMVADKVEVYSRPAAPESPGYQWLSDGSGVFEIAE 245

  Fly   235 DPRGDTLKRGSVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRMWSSKTVEEEVPVEEEAKP 299
               ...::.|:.|.::||.:.:||..|..|::::.|||.|::||:.:...:
  Rat   246 ---ASGVRPGTKIIIHLKSDCKDFANESRVQDVVTKYSNFVSFPLYLNGRR-------------- 293

  Fly   300 EKSEDDVEDEDAKVEEAEDEKPKTKKVSKTTWDWTLINDSKPIWTRKPAEVTEDEYTSFYKSLTK 364
                                                ||..:.||...|.:::|.::..||:.:.:
  Rat   294 ------------------------------------INTLQAIWMMDPKDISEFQHEEFYRYIAQ 322

  Fly   365 DSSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNYL 429
            ...:|....|:..:..:..:|:.|||:::|| .|:.......::.||.|:|.|..:..|::|.:|
  Rat   323 AYDKPRFILHYKTDAPLNIRSIFYVPEMKPS-MFDVSRELGSSVALYSRKVLIQTKATDILPKWL 386

  Fly   430 SFIRGVVDSDDLPLNVSRETLQQHKLIK----VIKKKLVRKVLDMLKKIDKEAYEKFWKEFSTNI 490
            .|:||||||:|:|||:|||.||:..||:    |::::|::..:|..|| |.|.|.||::::...:
  Rat   387 RFVRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKK-DAEKYAKFFEDYGLFM 450

  Fly   491 KLGVM--EDPSNRSRLAKLLRFQTS---NGKGVTSLAEYKERMKAKQEHIYYIAGANRAEVEKSP 550
            :.|::  .:...:..:|||||:::|   .|: :|||::|..||:|...:|||:...||...|.||
  Rat   451 REGIVTTAEQDIKEDIAKLLRYESSALPAGQ-LTSLSDYASRMQAGTRNIYYLCAPNRHLAEHSP 514

  Fly   551 FVERLLSKGYEVLYLVEAVDEYCISALPEFDGK-----------------KFQNVAKEGFQLNES 598
            :.|.:..|..|||:..|..||..:..|.|||.|                 ||::.:..|.:|:|.
  Rat   515 YYEAMKQKQTEVLFCYEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDTSPAGERLSEK 579

  Fly   599 EKSKKNFESLKSTFEPLVKWLNDVALKDQISKAQVSERLSNSPCALVAGVFGWTGN---MERLAM 660
            |.            |.|:.|:.: ||..:::..:|:.||...|..:.....|...:   |::||.
  Rat   580 ET------------EELMAWMRN-ALGSRVTNVKVTFRLDTHPAMVTVLEMGAARHFLRMQQLAK 631

  Fly   661 SNAHQKSDDPQRTYYLNQKKTLEINPRHPLMREL--LRRVEADEADDTAKDMAVMMFRTATLRSG 723
            :       ..:|...|  :.||||||||.|:::|  ||..|    .:.|:.:...::..|.:.:|
  Rat   632 T-------QEERAQLL--QPTLEINPRHTLIKKLNQLRERE----PELAQLLVDQIYENAMIAAG 683

  Fly   724  723
              Rat   684  683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp93	NP_651601.1	HATPase_Hsp90-like	82..275	CDD:340404	78/195 (40%)
		HSP90	257..748	CDD:459703	136/498 (27%)
Trap1	NP_001034090.1	PRK05218	89..704	CDD:235366	211/684 (31%)