Protein Alignment Gp93 and enpl-1

DIOPT Version :9

• Sequence 1: NP_651601.1
• Gene: Gp93 / 43354
• FlyBaseID: FBgn0039562
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001255536.1
• Gene: enpl-1 / 178014
• WormBaseID: WBGene00011480
• Length: 760
• Species: Caenorhabditis elegans
• Alignment Length: 792
• Identity: 487/792 - (61%)
• Similarity: 597/792 - (75%)
• Gaps: 42/792 - (5%)

  Fly     4 FLLVGLLLL----AGINQIAADDEA--ATTETIDLDLGSFKEGSRTDAETLKREEEAIQLDGLNV 62
            |||||.:.|    |.|..:.|:||.  |..||        ||      ||  |||::|:||||:|
 Worm     3 FLLVGFVALLAVSAFIPNVYAEDEIEDAPKET--------KE------ET--REEDSIKLDGLSV 51

  Fly    63 AQLKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLLALSNSKELET 127
            :|:||:|.||:|..||.|||||||||||||||||||||||||||||||:||||||:|::.::|..
 Worm    52 SQIKELRSKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRE 116

  Fly   128 NPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSKSEGLDMNDMI 192
            ..|:.::||||:||:.|||.|:|:|||.|||||||||||:|||::||:|:.|.:.|.. ...|:|
 Worm   117 TEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSD-QQQDLI 180

  Fly   193 GQFGVGFYSAFLVADRVVVTTKHNDDKQYIWESDANSFSITEDPRGDTLKRGSVISLYLKEEAQD 257
            ||||||||:|||||||||||||:|||.|||||||:.||:|::||||:|||||:.|:|||||||.|
 Worm   181 GQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSASFTISKDPRGNTLKRGTQITLYLKEEAAD 245

  Fly   258 FLEEDTVRELIRKYSQFINFPIRMWSSKTVEEEVPVEEEAKPEKSEDDVEDEDAKVEEAEDEKPK 322
            |||.||::.|:.||||||||.|.:|.|||...|..||||        ....||..|||.::|| |
 Worm   246 FLEPDTLKNLVHKYSQFINFDIFLWQSKTEMVEEAVEEE--------PATTEDGAVEEEKEEK-K 301

  Fly   323 TKKVSKTTWDWTLINDSKPIWTRKPAEVTEDEYTSFYKSLTKDSSEPLTQTHFIAEGEVTFKSLL 387
            ||||.||||||..:|:.||||.|||.:|.||||..||||:||||.|||:..||.|||||:|:|:|
 Worm   302 TKKVEKTTWDWEKVNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSIL 366

  Fly   388 YVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNYLSFIRGVVDSDDLPLNVSRETLQQ 452
            ||||..|::.|..||...:|||||||||||||:|.||:|.|||||||:|||||||||||||.|||
 Worm   367 YVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQ 431

  Fly   453 HKLIKVIKKKLVRKVLDMLKKIDKEAYEKFWKEFSTNIKLGVMEDPSNRSRLAKLLRFQTSN-GK 516
            |||:|||||||||||||||||:|...::.||.|||||||||||||||||.|||||||||:|| ..
 Worm   432 HKLLKVIKKKLVRKVLDMLKKLDGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDAD 496

  Fly   517 GVTSLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLLSKGYEVLYLVEAVDEYCISALPEFD 581
            ..|:||.|.||||.||:.|||:||.:|.|||.|||||||::||||||:|.||||||||.|:||::
 Worm   497 KTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYE 561

  Fly   582 GKKFQNVAKEGFQLNESEKSKKNFESLKSTFEPLVKWLNDVALKDQISKAQVSERLSNSPCALVA 646
            .||||||||||..:::.||:|:..:.|:..|:||..||.:.||||.|.||.||:||..||.||||
 Worm   562 SKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKETALKDLIEKAVVSQRLVKSPSALVA 626

  Fly   647 GVFGWTGNMERLAMSNAHQKSDDPQRTYYLNQKKTLEINPRHPLMRELLRRVEADEADDTAKDMA 711
            ..:||:|||||:..|.|:.|:.||.:.:|..||||.|||||||:::|||:||.|.|.|.||...|
 Worm   627 SSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINPRHPVIKELLKRVTASEEDTTAASTA 691

  Fly   712 VMMFRTATLRSGYMLQETSQFADSIEQMMRQTLGVSQDEQVEFDEE-EEDDAEETATGSQESGNA 775
            .::|.|||||||:.||:...|||.||.::||:|.||||.|||.::. ||.:.|..|        |
 Worm   692 KLLFETATLRSGFSLQDQVGFADRIEAVLRQSLDVSQDAQVETEQHIEEAEPEPEA--------A 748

  Fly   776 DDEEEEQQHDEL 787
            ::...|::|.||
 Worm   749 EETTIEEEHSEL 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp93	NP_651601.1	PRK05218	74..745	CDD:235366	437/671 (65%)
		HATPase_c	97..216	CDD:238030	79/118 (67%)
		HSP90	257..748	CDD:278607	310/491 (63%)
enpl-1	NP_001255536.1	PRK05218	59..724	CDD:235366	439/674 (65%)
		HATPase_c	84..242	CDD:214643	108/158 (68%)
		HSP90	245..735	CDD:278607	316/498 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159391
Domainoid	1	1.000	629	1.000	Domainoid score	I79
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2476
Inparanoid	1	1.050	923	1.000	Inparanoid score	I180
Isobase	1	0.950	-	0	Normalized mean entropy	S665
OMA	1	1.010	-	-		QHG54632
OrthoDB	1	1.010	-	-		D174605at33208
OrthoFinder	1	1.000	-	-		FOG0000295
OrthoInspector	1	1.000	-	-		oto17193
orthoMCL	1	0.900	-	-		OOG6_100204
Panther	1	1.100	-	-	LDO	PTHR11528
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X234
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.860