Protein Alignment Gp93 and Trap1

DIOPT Version :10

• Sequence 1: NP_651601.1
• Gene: Gp93 / 43354
• FlyBaseID: FBgn0039562
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_311405.4
• Gene: Trap1 / 1272492
• VectorBaseID: AGAMI1_013190
• Length: 713
• Species: Anopheles gambiae
• Alignment Length: 712
• Identity: 215/712 - (30%)
• Similarity: 366/712 - (51%)
• Gaps: 105/712 - (14%)

  Fly    68 IREKAK------KFTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLLALSNS---- 122
            ||::.|      |..||.|...::.::..|||.:||:|:|||:||||||::|.|.|..:::
Mosquito    69 IRDQEKAVGTSDKHEFQAETRMLLDIVARSLYSDKEVFVRELVSNASDALEKFRFLVQTSTGAAS 133

  Fly   123 -----KELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSK 182
                 :..|.:..|.|.|..:|:::.|.|.|:|||||..:|:.||||||:||:..|:.::::..:
Mosquito   134 DGEAGEFAEADRSLEIHIGTNKQDRQLTIQDTGIGMTRDELVANLGTIARSGSKQFMEQLKESGR 198

  Fly   183 SEGLDMNDMIGQFGVGFYSAFLVADRVVVTTKHN--DDKQYIWESD-ANSFSITEDPRGDTLKRG 244
            ....::.::||||||||||||:|||||.|.|:.:  ......|.|| :.:|.|.|   .:.:..|
Mosquito   199 GTQENVQNIIGQFGVGFYSAFMVADRVDVYTRSSRAGAPGLKWSSDGSGTFEIQE---AENVAIG 260

  Fly   245 SVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRMWSSKTVEEEVPVEEEAKPEKSEDDVEDE 309
            :.|.::||.:.::|.:||.:||:||:||.|:..||.:...:.
Mosquito   261 TKIVIHLKADCREFADEDRIREVIRRYSNFVGSPIFLNGKQA----------------------- 302

  Fly   310 DAKVEEAEDEKPKTKKVSKTTWDWTLINDSKPIWTRKPAEVTEDEYTSFYKSLTKDSSEPLTQTH 374
                                       |..:|||..:|.:||.:::..||:.:......|....|
Mosquito   303 ---------------------------NQIQPIWLMEPKQVTPEQHNEFYRFVGNTFDTPRFTLH 340

  Fly   375 FIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNYLSFIRGVVDSD 439
            :..:..::.::|||.|:.:|. .|.........:.||.|:|.|..:..:::|.:|.|::|||||:
Mosquito   341 YKTDVPLSIRALLYFPEGKPG-LFEMSRDADGGVALYTRKVLIQSKTENLLPKWLRFLKGVVDSE 404

  Fly   440 DLPLNVSRETLQQHKLIKVIKKKLVRKVLDML---KKIDKEAYEKFWKEFSTNIKLGVM--EDPS 499
            |:|||:|||.||...||:.::..|..:.|..|   .:.:.|:|:||:|::...:|.|::  ::..
Mosquito   405 DIPLNLSRELLQNSALIRKLRTALTNRTLRFLHDRSQKEPESYDKFYKDYGLFLKEGIVTSQEQQ 469

  Fly   500 NRSRLAKLLRFQTSNGKGVT-SLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLLSKGYEVL 563
            .:..:||||||:||.....| ||.||.:|....|:.|||:|..||...|.||:.|.|..:|.|||
Mosquito   470 EKEEIAKLLRFETSKEPNRTVSLPEYCQRQAEGQKDIYYLAAPNRTLAEASPYYESLKKRGIEVL 534

  Fly   564 YLVEAVDEYCISALPEFDGKKFQNVAKEGFQLNESEKSKK-----NFESLKSTFEPLVKWLNDVA 623
            :..||.||..:..|..:.||...:|.||..:.:.|...|.     ....||:..:.|:.||.| .
Mosquito   535 FCYEAYDELVLMQLGMYLGKNLVSVEKEMRRADASTDGKDADGLIEGSLLKTQIDELLPWLKD-K 598

  Fly   624 LKDQISKAQVSERLSNSPCALVAGVFGWTGNMERLA------MSNAHQKSDDPQRTYYLNQKKTL 682
            |..::|..:.:.:|...||.:         .:|.:|      .:.:|..|:  :..|.|.|.: .
Mosquito   599 LTGKVSNVKTTGKLDTHPCVV---------TVEEMAAARHFIKTQSHNISE--ENRYALLQPQ-F 651

  Fly   683 EINPRHPLMRELLRRVEADEADDTAKDMAVMMFRTATLRSGYMLQETSQFADSIEQMMRQTL 744
            ||||:||::::|.:...:|  .:.|:.:|..:|..|.:.:| ::.:......|:..::::.|
Mosquito   652 EINPKHPIIKKLHKLTSSD--PELAELLAKQLFSNAMVGAG-LVDDPRMLLTSMNDLLQKVL 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp93	NP_651601.1	HATPase_Hsp90-like	82..275	CDD:340404	79/204 (39%)
		HSP90	257..748	CDD:459703	138/505 (27%)
Trap1	XP_311405.4	None