Protein Alignment Gp93 and trap1

DIOPT Version :10

• Sequence 1: NP_651601.1
• Gene: Gp93 / 43354
• FlyBaseID: FBgn0039562
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_002932506.1
• Gene: trap1 / 100492593
• XenbaseID: XB-GENE-999249
• Length: 709
• Species: Xenopus tropicalis
• Alignment Length: 704
• Identity: 216/704 - (30%)
• Similarity: 375/704 - (53%)
• Gaps: 97/704 - (13%)

  Fly    40 GSRTDAETLKREEEAIQLDGLNVAQLKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELI 104
            |.|...:..:.:||.| |..: ::..:.::..|.|..||.|..:::.::..|||..||:|:||||
 Frog    60 GRRYTTQAAENKEEEI-LHKI-ISDTENVQGSASKHEFQAETKKLLDIVARSLYSEKEVFIRELI 122

  Fly   105 SNASDAIDKIRLLALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSG 169
            ||.|||::|:|...|:....|   ||:.|.::.|.:...|.|.|:|:|||..|||:||||||:||
 Frog   123 SNGSDALEKLRHNHLAQGSAL---PEMEIHLQTDADKGTLTIQDTGVGMTRDDLISNLGTIARSG 184

  Fly   170 TADFLAKMQDPSKSEGLDMNDMIGQFGVGFYSAFLVADRVVVTTKHNDDKQ--YIWESDANS-FS 231
            :..||..:|:.:.|.    :.:||||||||||||:|||:|||.::.:::..  |.|.||.:. |.
 Frog   185 SKAFLEALQNQADSS----SKIIGQFGVGFYSAFMVADKVVVYSQSSEEGSTGYCWSSDGSGVFE 245

  Fly   232 ITEDPRGDTLKRGSVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRMWSSKTVEEEVPVEEE 296
            :.|   ...::.|:.:.::||::.::|..||.|:|::.|||.|::||:.:...:
 Frog   246 LVE---ASGVRPGTKVVIHLKDDCKEFANEDRVKEVVTKYSNFVSFPLYLNGKR----------- 296

  Fly   297 AKPEKSEDDVEDEDAKVEEAEDEKPKTKKVSKTTWDWTLINDSKPIWTRKPAEVTEDEYTSFYKS 361
                                                   :|..:.:|...|.|:.|.::..||:.
 Frog   297 ---------------------------------------MNTLQALWMMDPKEIGEWQHEEFYRF 322

  Fly   362 LTKDSSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMP 426
            :.:...:|....|:.|:..:..:|:.|||:::|| .|:.......::.||.|:|.|..:..|::|
 Frog   323 IAQAYDKPRYMLHYKADAPLNIRSIFYVPEMKPS-MFDVSREMGSSVALYSRKVLIQTKAADILP 386

  Fly   427 NYLSFIRGVVDSDDLPLNVSRETLQQHKLIK----VIKKKLVRKVLDMLKKIDKEAYEKFWKEFS 487
            .:|.|:||||||:|:|||:|||.||:..||:    |::::|::..:|..|| |.|.|.||::::.
 Frog   387 KWLRFLRGVVDSEDIPLNLSRELLQESVLIRKLRDVLQRRLIKFFIDQSKK-DPEKYAKFFEDYG 450

  Fly   488 TNIKLGVM--EDPSNRSRLAKLLRFQTSN---GKGVTSLAEYKERMKAKQEHIYYIAGANRAEVE 547
            ..::.|::  .:...:..:||||||::|:   |: .|||.||..||:....:|||:...||...|
 Frog   451 LFMREGIVTTAEQEVKEDIAKLLRFESSSLPEGQ-QTSLTEYASRMQPGTRNIYYLCAPNRHLAE 514

  Fly   548 KSPFVERLLSKGYEVLYLVEAVDEYCISALPEFDGKKF----QNVAKEGFQLNESEKSKKNFESL 608
            .||:.|.:..|..|||:..|..||..:..|.|||.||.    .::..:.::.::.|:|....|.|
 Frog   515 HSPYYEAMKKKQTEVLFCYEQFDELTMLHLREFDKKKLISVETDIVVDHYKEDKFEESIPASERL 579

  Fly   609 -KSTFEPLVKWLNDVALKDQISKAQVSERLSNSPCALVAGVFGWTGNM---ERLAMSNAHQKSDD 669
             :...|.|:.|:.: .|..:|:..:|:.||...|..:.....|...:.   ::||.::
 Frog   580 SEKEAEDLMAWMRN-GLGTRITNVKVTPRLDTHPAMITVLEMGAARHFLRTQQLAKTS------- 636

  Fly   670 PQRTYYLNQKKTLEINPRHPLMRELLRRVEADEADDTAKDMAVMMFRTATLRSG 723
            .:|...|  :.|||||..|||:::|.:..:.::  :.||.:...::..|.:.:|
 Frog   637 EERAQIL--QPTLEINTGHPLIKKLWQLKDGEQ--ELAKLLLDQIYENAMIAAG 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp93	NP_651601.1	HATPase_Hsp90-like	82..275	CDD:340404	80/195 (41%)
		HSP90	257..748	CDD:459703	133/484 (27%)
trap1	XP_002932506.1	PRK05218	92..707	CDD:235366	209/670 (31%)