Protein Alignment mfrn and SLC25A28

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_112489.3
• Gene: SLC25A28 / 81894
• HGNCID: 23472
• Length: 364
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 154/292 - (52%)
• Similarity: 195/292 - (66%)
• Gaps: 14/292 - (4%)

  Fly     5 DYESLPT-TSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSL--SPPTKNMNIVSTLRTMITREG 66
            |||:||. .:|..:|.|||:||:|||.||||:|.||||||||  .|..:..|::..|..:|..||
Human    62 DYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEG 126

  Fly    67 LLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNYVISGA---VATLIHDAISSPT 128
            |.||:||.:....||||||:||||.||..|:..:........:::.:||   ||||:|||..:|.
Human   127 LWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGAAGCVATLLHDAAMNPA 191

  Fly   129 DVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKMNLE 193
            :|:|||||||||||..|..|||.:::.||..||||:|.|||.||:|:|.|||.||||.|...|.:
Human   192 EVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQ 256

  Fly   194 RKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQE--------TGLTRGMIEASRKIYHMAGP 250
            |:|||..|:.:||.|||.|||.||||||.||||||||        ||...||..|.|.:|.:.|.
Human   257 RRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGV 321

  Fly   251 LGFFRGTTARVLYSMPATAICWSTYEFFKFYL 282
            ..:|||..|||:|.:|:|||.||.|||||:.:
Human   322 TAYFRGVQARVIYQIPSTAIAWSVYEFFKYLI 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	147/275 (53%)
SLC25A28	NP_112489.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..60
		Solcar 1	70..158		47/87 (54%)
		Mito_carr	71..161	CDD:395101	47/89 (53%)
		Solcar 2	168..252		48/83 (58%)
		Mito_carr	169..253	CDD:395101	48/83 (58%)
		Solcar 3	259..352		52/92 (57%)
		Mito_carr	<279..356	CDD:395101	40/75 (53%)